{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:19:49Z","timestamp":1790680789239,"version":"4.1.0"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Hibiscus sabdariffa<\/jats:italic>\n L. (Rosella) has a long history of use in food preparation, herbal remedies, hot and cold beverages, food industry flavoring, and herbal drinks. More than 300 species of\n Hibiscus<\/jats:italic>\n are grown all over the world. It is an annual herbaceous shrub belonging to the family Malvacea. However, limited is known about the antimicrobial properties of\n H. sabdariffa<\/jats:italic>\n ; the purpose of this study was to investigate the antimicrobial activity of\n H. sabdariffa<\/jats:italic>\n (Rosella) extract against a range of pathogens, including\n Staphylococcus aureus<\/jats:italic>\n ,\n Escherichia coli<\/jats:italic>\n ,\n Pseudomonas aeruginosa<\/jats:italic>\n , and\n Candida albicans<\/jats:italic>\n . The results of the study showed that\n H. sabdariffa<\/jats:italic>\n (Rosella) extract had a significant antimicrobial effect, against\n S. aureus<\/jats:italic>\n and\n E. coli<\/jats:italic>\n . Further the minimum inhibitory concentration (MIC) shows 128 \u03bcg\/mL concentration followed by\n E. coli<\/jats:italic>\n 256 \u03bcg\/mL. The biocompatibility of crude metabolites shows highly compatible with Red blood cells (RBC\u2019s). This finding suggests that the crude metabolites of\n H. sabdariffa<\/jats:italic>\n (Rosella) could be the source to control the human pathogens.\n <\/jats:p>","DOI":"10.4103\/jpbs.jpbs_527_23","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T12:26:57Z","timestamp":1713270417000},"page":"S1191-S1194","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Antibacterial Activity of Hibiscus sabdariffa (Rosella) Using Methanolic Extract"],"prefix":"10.4103","volume":"16","author":[{"given":"Keerthika","family":"Venkatesan","sequence":"first","affiliation":[{"name":"Department of Microbiology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha Nagar, Thandalam, Chennai, Tamil Nadu, 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