{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:20:47Z","timestamp":1787840447057,"version":"build-2784847793"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study aimed to compare the maternal and neonatal outcomes of elective labor induction at 39 weeks with expectant management in low-risk nulliparous women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      A randomized controlled trial was conducted at ACS Medical College and Hospital, Chennai, over 6 months. A total of 100 low-risk nulliparous women with singleton pregnancies between 38 weeks 0 days and 38 weeks 6 days of gestation were randomized into two groups: labor induction (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 50) and expectant management (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 50). Statistical analysis was performed using an independent t-test to compare two groups, with a significance level of\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The labor induction group had a shorter labor duration (7.5 \u00b1 2.3 vs. 9.2 \u00b1 2.7 h;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.003). The mode of delivery was similar, with vaginal births at 72% versus 64% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.34) and cesarean rates at 28% versus 36% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.42). Maternal complications (postpartum hemorrhage,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.21; infection,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.69) and neonatal outcomes (Apgar scores, birth weight, NICU admissions) showed no significant differences.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Labor induction at 39 weeks in low-risk nulliparous women shortens labor duration without increasing cesarean delivery rates, maternal complications, or adverse neonatal outcomes. These findings support the safety of elective labor induction in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_544_25","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:02:04Z","timestamp":1750208524000},"page":"S1852-S1854","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Labor Induction versus Expectant Management: Evaluating Maternal and Neonatal Outcomes in Low-Risk Nulliparous Women"],"prefix":"10.4103","volume":"17","author":[{"given":"Divya Raghavendra","family":"Rao","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, ACS Medical College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. D.","family":"Abilashini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, ACS Medical College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijayalakshmi","family":"Gnanasekaran","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, ACS Medical College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"R1-20250618","doi-asserted-by":"crossref","first-page":"265.e1","DOI":"10.1016\/j.ajog.2014.03.021","article-title":"Neonatal outcomes in early term birth","volume":"211","author":"Parikh","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"R2-20250618","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/01.AOG.0000452744.06088.48","article-title":"Practice bulletin no. 146: Management of late-term and post term pregnancies","volume":"124","year":"2014","journal-title":"Obstet Gynecol"},{"key":"R3-20250618","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/AOG.0b013e3181b48ef5","article-title":"ACOG practice bulletin no. 107: induction of labor","volume":"114","year":"2009","journal-title":"Obstet Gynecol"},{"key":"R4-20250618","first-page":"25","article-title":"Maternal and neonatal morbidity among nulliparous women undergoing elective induction of labor","volume":"56","author":"Vardo","year":"2011","journal-title":"J Reprod Med"},{"key":"R5-20250618","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/S1701-2163(16)34372-9","article-title":"Outcomes of elective labour induction and elective caesarean section in low-risk pregnancies between 37 and 41 weeks' gestation","volume":"31","author":"Dunne","year":"2009","journal-title":"J Obstet Gynaecol Can"},{"key":"R6-20250618","doi-asserted-by":"crossref","first-page":"657","DOI":"10.2471\/BLT.08.061226","article-title":"Elective induction versus spontaneous labour in Latin America","volume":"89","author":"Guerra","year":"2011","journal-title":"Bull World Health Organ"},{"key":"R7-20250618","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1097\/AOG.0b013e31820caf12","article-title":"Elective induction compared with expectant management in nulliparous women with an unfavorable cervix","volume":"117","author":"Osmundson","year":"2011","journal-title":"Obstet Gynecol"},{"key":"R8-20250618","doi-asserted-by":"crossref","first-page":"249.e1","DOI":"10.1016\/j.ajog.2014.03.016","article-title":"Maternal and neonatal outcomes in electively induced low-risk term pregnancies","volume":"211","author":"Gibson","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"R9-20250618","doi-asserted-by":"crossref","first-page":"e2838","DOI":"10.1136\/bmj.e2838","article-title":"Outcomes of elective induction of labour compared with expectant management: Population based study","volume":"344","author":"Stock","year":"2012","journal-title":"BMJ"},{"key":"R10-20250618","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/ijgo.15597","article-title":"Elective induction of labor versus expectant management at 39 weeks among low-risk nulliparous pregnant women: A randomized controlled trial in India (ELITE-39 trial)","volume":"167","author":"Lalithadevi","year":"2024","journal-title":"Int J Gynaecol Obstet"},{"key":"R11-20250618","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1056\/NEJMoa1800566","article-title":"Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal\u2013Fetal Medicine Units Network. Labor induction versus expectant management in low-risk nulliparous women","volume":"379","author":"Grobman","year":"2018","journal-title":"N Engl J Med"},{"key":"R12-20250618","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/AOG.0b013e3181e10c5c","article-title":"Labor induction and the risk of a cesarean delivery among nulliparous women at term","volume":"116","author":"Ehrenthal","year":"2010","journal-title":"Obstet Gynecol"},{"key":"R13-20250618","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/birt.12286","article-title":"Labor induction and cesarean delivery: A prospective cohort study of first births in Pennsylvania, USA","volume":"44","author":"Kjerulff","year":"2017","journal-title":"Birth"},{"key":"R14-20250618","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3390\/diagnostics13010038","article-title":"Maternal and neonatal outcomes of elective induction of labor at 39 or more weeks: A prospective, observational study","volume":"13","author":"Lee","year":"2022","journal-title":"Diagnostics (Basel)"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_544_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:22:58Z","timestamp":1787836978000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_544_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":14,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_544_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-02-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}