{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:23:11Z","timestamp":1787772191375,"version":"build-2784847793"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>\n                    Nonessential heavy metals are toxic to human health. In this study, mercury, a hazardous metal, was detected by colorimetric analysis using\n                    <jats:italic toggle=\"yes\">Zingiber (Z.) officinale<\/jats:italic>\n                    . The eco-friendliness of this method was also emphasized. The ultraviolet (UV) spectrum is a broad peak observed at 200\u2013250 nm in\n                    <jats:italic toggle=\"yes\">Z. officinale<\/jats:italic>\n                    leaf extracts. The UV spectrum of green synthesized\n                    <jats:italic toggle=\"yes\">Z. officinale<\/jats:italic>\n                    exhibited an absorption band of 286 nm, which confirms the nanoparticle (NP) synthesis. Fourier transform infrared (FTIR) analysis of the vibrational peak around 3307 cm\u22121 is assigned to \u03bd(O\u2013H) stretching that could possibly emanate from carbohydrates or phenolics. The peaks found around 2917 and 2849 cm\u22121 are ascribed to the \u2013C-H stretch of the alkyl group, and the peak around 1625 cm\u22121 is due to the enolic \u03b2-diketones or -C = O stretch of carboxylic acids, while the corresponding -C-O stretch is observed around 1375 and 1029 cm\u22121. The assignment of peaks is similar. It is clear from the scanning electron microscope (SEM) image that the constituent parts were nonuniform, sphere-shaped, agglomerated, and of an average size of 30.9 nm. X-ray diffraction (XRD) analysis was used to determine the structural characteristics and crystalline nature of\n                    <jats:italic toggle=\"yes\">Z. officinale<\/jats:italic>\n                    . The observed intensity peaks at 32.35\u00b0, 36.69\u00b0, 39.24\u00b0, 44.76\u00b0, 59.42\u00b0, and 67.35\u00b0 are, respectively, of the\n                    <jats:italic toggle=\"yes\">Z. officinale<\/jats:italic>\n                    diffraction 2\u03b8 values, which correspond to the standard database values. The synthesized copper NPs synthesized tested antibacterial properties against various strains of microorganisms, including\n                    <jats:italic toggle=\"yes\">Escherichia coli:<\/jats:italic>\n                    25 \u03bcg\/mL 2.01 \u00b1 0.11 and 100 \u03bcg\/mL 5.37 \u00b1 0.12,\n                    <jats:italic toggle=\"yes\">Staphylococcus (S.) aureus:<\/jats:italic>\n                    25 \u03bcg\/mL 1.05 \u00b1 0.71 and 100 \u03bcg\/mL 11.43 \u00b1 1.27,\n                    <jats:italic toggle=\"yes\">Streptococcus mutans:<\/jats:italic>\n                    25 \u03bcg\/mL 02.01 \u00b1 0.1 and 100 \u03bcg\/mL 15.67 \u00b1 0.17, and\n                    <jats:italic toggle=\"yes\">Enterococcus faecalis<\/jats:italic>\n                    : 25 \u03bcg\/mL 03.11 \u00b1 0.7 and 100 \u03bcg\/mL 18.32 \u00b1 0.2. The short novelty of\n                    <jats:italic toggle=\"yes\">Z. officinale<\/jats:italic>\n                    lies in its potential relevance to human health, as it has been found to possess bioactive compounds with various medicinal properties, such as antimicrobial, antioxidant, and anti-inflammatory activities, making it a promising natural resource for therapeutic applications.\n                  <\/jats:p>","DOI":"10.4103\/jpbs.jpbs_547_23","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T12:27:49Z","timestamp":1713270469000},"page":"S1226-S1232","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Phytochemical Analysis of Silver Nanoparticles of Zingiber officinale and Evaluation for Its Antibacterial Property"],"prefix":"10.4103","volume":"16","author":[{"given":"Goutham","family":"Krishna","sequence":"first","affiliation":[{"name":"Natural Products and Nanobiotechnology Research Lab, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), (Saveetha Deemed to be University), Thandalam, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azhagu Madhavan","family":"Sivalingam","sequence":"additional","affiliation":[{"name":"Natural Products and Nanobiotechnology Research Lab, Department of Community Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), (Saveetha Deemed to be University), Thandalam, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Brahma","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), (Saveetha Deemed to be University), Thandalam, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arockia","family":"Alex","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), (Saveetha Deemed to be University), Thandalam, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/fft2.58","article-title":"Nanotechnology: Current applications and future scope in food","volume":"2","author":"Sahoo","year":"2021","journal-title":"Food Frontiers"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"16074","DOI":"10.1038\/s41598-019-52473-2","article-title":"Synergistic antibacterial effects of metallic nanoparticle combinations","volume":"9","author":"Bankier","year":"2019","journal-title":"Sci Rep"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"641481","DOI":"10.3389\/fphy.2021.641481","article-title":"A mini review of antibacterial properties of ZnO nanoparticles","volume":"9","author":"Gudkov","year":"2021","journal-title":"Front Phys"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.molliq.2018.02.010","article-title":"Green synthesis of copper nanoparticles by fruit extract of Ziziphus spina-christi (L.) 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