{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T11:55:08Z","timestamp":1792410908154,"version":"4.4.0"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 5","license":[{"start":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:00:00Z","timestamp":1760313600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Trismus, a common complication of oral squamous cell carcinoma (OSCC) treatment, can significantly affect patients\u2019 quality of life (QoL). Understanding its prevalence and impact is crucial for improving patient care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the prevalence of trismus and its effects on QoL in patients undergoing treatment for OSCC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This prospective research involved 150 OSCC patients undergoing surgery, radiotherapy, or combined therapy. Trismus was defined as maximum interincisal opening (MIO) \u226435 mm, measured at baseline, 3, and 6 months post-treatment. QoL was estimated using the EORTC QLQ-C30 and QLQ-H and N35 questionnaires.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Trismus prevalence was 28% at baseline, increasing to 55% at 3 months and 47% at 6 months. Patients with trismus had significantly lower QoL scores in domains such as pain, emotional well-being, and social interactions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Trismus is highly prevalent in OSCC patients and profoundly impacts QoL, highlighting the need for early interventions and targeted rehabilitation strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_558_25","type":"journal-article","created":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T16:05:19Z","timestamp":1760457919000},"page":"S3491-S3493","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of Trismus and its Effects on Quality of Life in Patients Treated for Oral Squamous Cell Carcinoma: A Prospective Study"],"prefix":"10.4103","volume":"17","author":[{"given":"Anita","family":"Mohanty","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Kalinga Institute of Dental Science, KIIT Deemed to be University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monalisa","family":"Dash","sequence":"additional","affiliation":[{"name":"Department of Pathology, ICARE Institute of Medical Sciences and Research, Haldia, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mudita","family":"Chaturvedi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Department of Dental Research Cell, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heena","family":"Dixit","sequence":"additional","affiliation":[{"name":"Department of Hospital and Healthcare Management, Dr. D. Y. Patil Deemed to be University, Navi Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dheeraj","family":"Voulligonda","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Mamata Institute of Dental Sciences, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suveet","family":"Mathur","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Geetanjali Dental and Research Institute, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,10,13]]},"reference":[{"key":"R1-20260217","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000446117","article-title":"Global epidemiology of head and neck cancers: A continuing challenge","volume":"91","author":"Gupta","year":"2016","journal-title":"Oncology"},{"key":"R2-20260217","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.radonc.2013.03.005","article-title":"Dysphagia and trismus after concomitant chemo-Intensity-Modulated Radiation Therapy (chemo-IMRT) in advanced head and neck cancer;dose-effect relationships for swallowing and mastication structures","volume":"106","author":"van der Molen","year":"2013","journal-title":"Radiother Oncol"},{"key":"R3-20260217","doi-asserted-by":"crossref","first-page":"15347354211006474","DOI":"10.1177\/15347354211006474","article-title":"Interventions for trismus in head and neck cancer patients: A systematic review of randomized controlled trials","volume":"20","author":"Chee","year":"2021","journal-title":"Integr Cancer Ther"},{"key":"R4-20260217","doi-asserted-by":"crossref","first-page":"2352","DOI":"10.1002\/hed.24859","article-title":"Exercise therapy for trismus secondary to head and neck cancer: A systematic review","volume":"39","author":"Kamstra","year":"2017","journal-title":"Head Neck"},{"key":"R5-20260217","first-page":"2920418","article-title":"Assessment of quality of life of free anterolateral thigh flap for reconstruction of tissue defects of total or near-Total glossectomy","author":"Zhang","year":"2020","journal-title":"J Oncol 2020"},{"key":"R6-20260217","doi-asserted-by":"crossref","first-page":"11795549211036898","DOI":"10.1177\/11795549211036898","article-title":"Radiation-induced fibrosis in patients with head and neck cancer: A review of pathogenesis and clinical outcomes","volume":"16","author":"Ramia","year":"2022","journal-title":"Clin Med Insights Oncol"},{"key":"R7-20260217","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1200\/OP.20.00266","article-title":"Restricted mouth opening in head and neck cancer: Etiology, prevention, and treatment","volume":"16","author":"Abboud","year":"2020","journal-title":"JCO Oncol Pract"},{"key":"R8-20260217","first-page":"1825","article-title":"Self-reported trismus: Prevalence, severity and impact on quality of life in oropharyngeal cancer survivorship: A cross-sectional survey report from a comprehensive cancer center","volume":"29","author":"Cardoso","year":"2021","journal-title":"Support Care Cancer"},{"issue":"(Suppl 1)","key":"R9-20260217","doi-asserted-by":"crossref","first-page":"S182","DOI":"10.4103\/jpbs.jpbs_60_22","article-title":"Evaluation of efficiency of dyes in detection of cancer cells: An original research","volume":"14","author":"Ravindranath","year":"2022","journal-title":"J Pharm Bioallied Sci"},{"key":"R10-20260217","doi-asserted-by":"crossref","first-page":"212","DOI":"10.4103\/ijabmr.IJABMR_221_18","article-title":"Human papillomavirus detection in oropharyngeal squamous cell carcinoma using p16 immunohistochemistry","volume":"9","author":"Sabu","year":"2019","journal-title":"Int J Appl Basic Med Res"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_558_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:13:55Z","timestamp":1787166835000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_558_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,13]]},"references-count":10,"journal-issue":{"issue":"Suppl 5","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_558_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,13]]},"assertion":[{"value":"2025-02-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}