{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:08:56Z","timestamp":1791846536986,"version":"4.3.4"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Microbial and fungal growth, particularly\n                      <jats:italic toggle=\"yes\">Candida albicans<\/jats:italic>\n                      , is a major issue with the usage of maxillofacial silicone material, which can lead to chronic infection, inflammation, and silicone material degradation, for which the development of an antimicrobial silicone elastomer has become crucial.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>This study was designed to determine the efficacy of adding chitosan nanoparticles (1.5%, 3%, and 5% by weight) to silicone matrix on antifungal activity. Eighty specimens were fabricated with varying concentrations of chitosan and separated into four groups [C1 (control), C2 (1.5%wt chitosan reinforced silicone), C3 (3%wt chitosan\/silicone), and C4 (5%wt chitosan\/silicone)]. An antifungal test was conducted on each group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The inhibition zone was concentration dependent in antifungal tests; as the concentration increased, the inhibition zone grew as well.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Improvement in the antifungal activity of silicone was demonstrated when chitosan nanoparticles were incorporated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_604_24","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T13:34:08Z","timestamp":1725543248000},"page":"S3239-S3241","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of Antifungal Activity of MaxilloFacial Silicone Elastomer Reinforced with Chitosan Nanoparticles\u2014An In vitro Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Ailneni Nivya","family":"Sri","sequence":"first","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Gitam Dental College and Hospital, Visakhapatnam, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shruti Vishal","family":"Dev","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonali","family":"Perti","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirmala","family":"Poddar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sourav Kumar","family":"Pati","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Trupti Dental Clinic and Implant Centre, Jamshedpur, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pritam","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, 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