{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:33:57Z","timestamp":1787762037843,"version":"build-2784847793"},"reference-count":57,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Resistin is a small adipocyte-specific secretory hormone molecule. It has been associated with a number of cellular and metabolic processes. It has also been essentially implicated to have a vital role in the interplay between insulin resistance, obesity, and type II diabetes. Numerous clinical studies have demonstrated an association between many pathological illnesses with elevated serum resistin levels. It has also been shown to affect and modulate various molecular processes such as atherosclerosis, cancer cell metabolism, and inflammation. Periodontitis is a widespread inflammatory disease affecting human beings. Periapical periodontitis is an inflammatory disease that manifests as a sequela of untreated dental caries. Therefore, in this article, we summarize the divergent physiological roles played by resistin and its association with the mechanism of various pathologies. Moreover, current scientific studies discussing its association and role in common dental pathologies, periodontitis, and apical periodontitis are reviewed.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_655_22","type":"journal-article","created":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T02:07:24Z","timestamp":1689127644000},"page":"S31-S35","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":12,"title":["Role of Resistin in Various Diseases with Special Emphasis on Periodontal and Periapical Inflammation \u2013 A Review"],"prefix":"10.4103","volume":"15","author":[{"given":"Mona Awad","family":"Kamil","sequence":"first","affiliation":[{"name":"Division of Periodontics, Department of Preventive Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Wali","family":"Peeran","sequence":"additional","affiliation":[{"name":"Division of Periodontics, Department of Preventive Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia"},{"name":"Saveetha Dental College and Hospitals, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Nahid","family":"Basheer","sequence":"additional","affiliation":[{"name":"Department of Conservative Dental Sciences, College of Dentistry, Faculty of Denticstry, Jazan University, Jazan, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Elhassan","sequence":"additional","affiliation":[{"name":"Libyan Authority of Scientific Research, Tripoli Libya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Nazish","family":"Alam","sequence":"additional","affiliation":[{"name":"Division of Periodontics, Department of Preventive Dental Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhumala","family":"Thiruneervannan","sequence":"additional","affiliation":[{"name":"Department of Periodontics, VMS Dental College, Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,7,5]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/35053000","article-title":"The hormone resistin links obesity to diabetes","volume":"409","author":"Steppan","year":"2001","journal-title":"Nature"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0014-5793(03)00708-7","article-title":"Resistin is expressed in different rat tissues and is regulated in a tissue- and gender-specific manner","volume":"548","author":"Nogueiras","year":"2003","journal-title":"FEBS 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