{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:25:35Z","timestamp":1787840735629,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","license":[{"start":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T00:00:00Z","timestamp":1749600000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Mental health issues, particularly stress and depression, are highly prevalent among the elderly, especially those residing in old age homes. Elevated serum cortisol levels are associated with prolonged stress and depression, leading to further health complications. This study evaluates the effectiveness of a mindfulness-based approach in reducing stress, depression, and serum cortisol levels among elderly individuals in institutional care.<\/jats:p>\n <\/jats:sec>\n \n Materials and methodology:<\/jats:title>\n This quasi-experimental study was conducted in two old age homes in Chennai. A total of 48 elderly participants (aged 60\u201380 years) were selected using convenience sampling and divided into experimental (mindfulness intervention) and control (routine care) groups. The 12 weeks mindfulness intervention included techniques such as 5-Senses Grounding, Body Scan Meditation, mindfulness eating, Mindful Walking and breathing space meditation. Data were collected at baseline and 12 weeks post-intervention using the Perceived Stress Scale (PSS), Geriatric Depression Scale-Short Form (GDS-SF), and serum cortisol levels.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Post-intervention, 83.33% of the experimental group reported low stress compared to 12.50% in the control group (\n P<\/jats:italic>\n = 0.001). Depression also significantly improved, with 41.67% achieving expected levels in the experimental group, while 70.83% in the control group remained moderately depressed (\n P<\/jats:italic>\n = 0.001). However, serum cortisol levels showed no significant reduction (\n P<\/jats:italic>\n = 0.21).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Mindfulness-based interventions effectively reduced stress and depression but did not significantly impact serum cortisol levels. Future research should examine longer interventions and alternative biomarkers. Nurses are key in integrating mindfulness into elderly care to enhance mental well-being.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_655_25","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T07:00:15Z","timestamp":1749711615000},"page":"S2737-S2740","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Effectiveness of Mindfulness-based Approaches on Stress, Depression, and Serum Cortisol among Elderly in Old Age Homes"],"prefix":"10.4103","volume":"17","author":[{"given":"Jayalakshmi","family":"Lakshmanan","sequence":"first","affiliation":[{"name":"Department of Psychiatric Nursing, Saveetha College of Nursing, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhuvaneswari","family":"Gopalakrishnan","sequence":"additional","affiliation":[{"name":"Department of Community Health Nursing, Saveetha College of Nursing, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shankar Shanmugam","family":"Rajendran","sequence":"additional","affiliation":[{"name":"Department of Nursing Education, College of Nursing, Madras Medical College, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,11]]},"reference":[{"key":"R2-20250930","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1177\/08982643211004174","article-title":"Social isolation among older adults in long-term care: A scoping review","volume":"33","author":"Boamah","year":"2021","journal-title":"J Aging Health"},{"key":"R3-20250930","doi-asserted-by":"crossref","first-page":"1868","DOI":"10.4103\/jfmpc.jfmpc_1850_20","article-title":"Prevalence of depression amongst the elderly population in old age homes of Mangalore city","volume":"10","author":"Kumar","year":"2021","journal-title":"J Family Med Prim Care"},{"key":"R4-20250930","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.3390\/cells12232726","article-title":"The role of cortisol in chronic stress, neurodegenerative diseases, and psychological disorders","volume":"12","author":"Knezevic","year":"2023","journal-title":"Cells"},{"key":"R5-20250930","doi-asserted-by":"crossref","first-page":"30187","DOI":"10.1038\/srep30187","article-title":"Prolonged secretion of cortisol as a possible mechanism underlying stress and depressive behaviour","volume":"6","author":"Qin","year":"2016","journal-title":"Sci Rep"},{"key":"R6-20250930","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1186\/s12889-024-17759-9","article-title":"Effect of mindfulness-based stress reduction (MBSR) program on depression, emotion regulation, and sleep problems: A randomized controlled trial study on depressed elderly","volume":"24","author":"Javadzade","year":"2024","journal-title":"BMC Public Health"},{"key":"R7-20250930","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/bmb\/ldab005","article-title":"Mindfulness-based interventions: An overall review","volume":"138","author":"Zhang","year":"2021","journal-title":"Br Med Bull"},{"key":"R8-20250930","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1186\/s12889-024-17759-9","article-title":"Effect of mindfulness-based stress reduction (MBSR) program on depression, emotion regulation, and sleep problems: A randomized controlled trial study on depressed elderly","volume":"24","author":"Javadzade","year":"2024","journal-title":"BMC Public Health"},{"key":"R9-20250930","doi-asserted-by":"crossref","first-page":"804269","DOI":"10.3389\/fpsyt.2021.804269","article-title":"Effects of mindfulness-based cognitive therapy on peripheral markers of stress and inflammation in older-adults with depression and anxiety: A parallel analysis of a randomized controlled trial","volume":"12","author":"Belliveau","year":"2021","journal-title":"Front Psychiatry"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_655_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:27:57Z","timestamp":1787837277000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_655_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,11]]},"references-count":8,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_655_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,11]]},"assertion":[{"value":"2025-03-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}