{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:22:52Z","timestamp":1787775772590,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Introduction:<\/jats:title>\n This study investigates the impact of commonly prescribed pediatric medications on resin-modified glass ionomer cement (RMGIC), which is widely used in pediatric dentistry in India. The interaction between these medications and RMGIC could affect the material\u2019s durability and effectiveness.<\/jats:p>\n <\/jats:sec>\n \n Methodology:<\/jats:title>\n Sixty RMGIC specimens were divided into five groups, each exposed to different pediatric medications: antibiotic syrup, antipyretic syrup, vitamin syrup, antitussive syrup, and distilled water (control). Microhardness and surface roughness were measured before and after a 14-day immersion period. Statistical analysis was conducted using one-way ANOVA and post-hoc Tukey\u2019s test.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n All pediatric medications significantly affected RMGIC, with antitussive syrup showing the most substantial impact. Microhardness decreased by up to 18.40%, and surface roughness increased by up to 21.40%. The control group showed no significant changes.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Pediatric medications, particularly those with acidic properties, compromise the durability of RMGIC. Further research is needed to develop more resistant materials or protective measures.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_688_24","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T13:08:52Z","timestamp":1726060132000},"page":"S3185-S3187","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Different Pediatric Medications on RMGIC: A Comparative Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Ahtesham A.","family":"Qurishi","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jizan University, Jazan, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed S.","family":"Al Dira","sequence":"additional","affiliation":[{"name":"Dental Intern, College of Dentistry, Jizan University, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal H.","family":"Sholan","sequence":"additional","affiliation":[{"name":"Dental Students, College of Dentistry, Jizan University, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahad E.","family":"Abzoah","sequence":"additional","affiliation":[{"name":"Dental Students, College of Dentistry, Jizan University, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahdi A.","family":"Hakami","sequence":"additional","affiliation":[{"name":"Dental Intern, College of Dentistry, Jizan University, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emad","family":"Malhan","sequence":"additional","affiliation":[{"name":"Dental Intern, College of Dentistry, Jizan University, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahad M.","family":"Moafa","sequence":"additional","affiliation":[{"name":"Dental Intern, College of Dentistry, Jizan University, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"R1-20241227","doi-asserted-by":"crossref","first-page":"169","DOI":"10.12701\/yujm.2020.00374","article-title":"Current aspects and prospects of glass ionomer cements for clinical dentistry","volume":"37","author":"Park","year":"2020","journal-title":"Yeungnam Univ J Med"},{"key":"R2-20241227","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.3390\/children9071026","article-title":"The effects of different pediatric drugs and brushing on the color stability of esthetic restorative materials used in pediatric dentistry:An in vitro study","volume":"9","author":"Almutairi","year":"2022","journal-title":"Children"},{"key":"R3-20241227","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jdsr.2021.11.004","article-title":"Impact of direct restorative dental materials on surface root caries treatment. Evidence based and current materials development:A systematic review","volume":"58","author":"Tonprasong","year":"2022","journal-title":"Jpn Dent Sci Rev"},{"key":"R4-20241227","first-page":"43","article-title":"Toward dental caries:Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials","volume":"4","author":"Balhaddad","year":"2018","journal-title":"Bioact Mater"},{"key":"R5-20241227","doi-asserted-by":"crossref","first-page":"611","DOI":"10.4103\/0970-2113.192878","article-title":"The burden of segregated respiratory diseases in India and the quality of care in these patients:Results from the Asia-Pacific Burden of Respiratory Diseases study","volume":"33","author":"Ghoshal","year":"2016","journal-title":"Lung India Off Organ Indian Chest Soc"},{"key":"R6-20241227","first-page":"123","article-title":"Effect of paediatric liquid medications on surface roughness of dental restorative materials","volume":"7","author":"Nalwade","year":"2019","journal-title":"J Adv Med Dent Sci Res"},{"key":"R7-20241227","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1007\/s41779-024-00991-2","article-title":"Effect of pediatric drugs on the color stability of dental restorative materials currently used in pediatric dentistry","volume":"60","author":"\u00c7apan","year":"2024","journal-title":"J Aust Ceramic Soc"},{"key":"R8-20241227","first-page":"e42764","article-title":"Comparative evaluation on the effects of three pediatric syrups on microhardness, roughness and staining of the primary teeth enamel:An in-vitro study","volume":"15","author":"Mukundan","year":"2023","journal-title":"Cureus"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_688_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:42:07Z","timestamp":1787773327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_688_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,11]]},"references-count":8,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_688_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,11]]},"assertion":[{"value":"2024-06-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}