{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:24:14Z","timestamp":1787775854466,"version":"build-2784847793"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Spinal anesthesia is increasingly used in neonates to minimize respiratory complications such as apnea and bradycardia. It also avoids delayed recovery associated with general anesthesia (GA) and provides stable intraoperative conditions for infraumbilical surgeries. To assess the efficiency of subarachnoid block (SAB) as a sole anesthetic method in neonates undergoing infraumbilical surgeries and evaluate hemodynamic parameters (PR, BP, SPO\n                      <jats:sub>2<\/jats:sub>\n                      , RR) and adverse events.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This prospective observational study was conducted in the Department of Anesthesiology, M.Y. Hospital and MGM Medical College, Indore, with 84 neonates (0\u201328 days) undergoing infraumbilical surgeries. SAB was administered at the L4-L5 interspinous space using 0.5% hyperbaric bupivacaine (0.5 mg\/kg).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age was 14.39 days with 62.5% males. Hemodynamic parameters remained stable (HR: 162.5 bpm, SPO\n                      <jats:sub>2:<\/jats:sub>\n                      99.2\u201399.36%). The mean surgery duration was 38.3 minutes. Incidence of adverse effects was minimal.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>SAB is a safe, simple, and cost-effective alternative to GA ensuring hemodynamic stability and minimal postoperative complications in neonates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_696_25","type":"journal-article","created":{"date-parts":[[2025,5,10]],"date-time":"2025-05-10T04:01:47Z","timestamp":1746849707000},"page":"S293-S295","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Prospective Clinical Study to Assess the Efficiency of Subarachnoid Block as Sole Anesthetic Method in Neonates Undergoing Infraumbilical Surgeries"],"prefix":"10.4103","volume":"17","author":[{"given":"Kaushal","family":"Kabir","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kovvuri","family":"Jhansi","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aseem","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshay R.","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Banjare","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,5,10]]},"reference":[{"key":"R1-20250513","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1111\/j.1365-2044.1989.tb11348.x","article-title":"Spinal anesthesia in infants born prematurely","volume":"44","author":"Gallagher","year":"1989","journal-title":"Anaesthesia"},{"key":"R2-20250513","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.bpa.2010.02.018","article-title":"Spinal anesthesia in the neonate","volume":"24","author":"Frawley","year":"2010","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"R3-20250513","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1093\/bja\/86.3.366","article-title":"Post-operative recovery after inguinal herniotomy in ex-premature infants: Comparison between sevoflurane and spinal anesthesia","volume":"86","author":"William","year":"2001","journal-title":"Br J Anaesth"},{"key":"R4-20250513","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/BF03007615","article-title":"Spinal anesthesia for inguinal hernia repair in high-risk neonates","volume":"38","author":"Webster","year":"1991","journal-title":"Can J Anaesth"},{"key":"R5-20250513","doi-asserted-by":"crossref","first-page":"324","DOI":"10.4103\/0259-1162.143124","article-title":"Spinal anesthesia in infant and children","volume":"8","author":"Verma","year":"2014","journal-title":"Anesth Essays Res"},{"key":"R6-20250513","first-page":"22","article-title":"Pediatric spinal anesthesia","volume":"25","author":"Troncin","year":"2009","journal-title":"Update Anaesth"},{"key":"R7-20250513","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1460-9592.2011.03693.x","article-title":"Spinal blocks","volume":"22","author":"Kokki","year":"2012","journal-title":"Paediatr Anaesth"},{"key":"R8-20250513","doi-asserted-by":"crossref","first-page":"691","DOI":"10.3346\/jkms.2003.18.5.691","article-title":"Postoperative outcome in formerly premature infants undergoing herniorrhaphy: Comparison of spinal and general anesthesia","volume":"18","author":"Kim","year":"2003","journal-title":"J Korean Med Sci"},{"key":"R9-20250513","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1136\/adc.69.6.623","article-title":"Regional anesthesia for surgical treatment of inguinal hernia in preterm babies","volume":"69","author":"Gallagher","year":"1993","journal-title":"Arch Dis Child"},{"key":"R10-20250513","doi-asserted-by":"crossref","first-page":"324","DOI":"10.4103\/0259-1162.143124","article-title":"Spinal anesthesia in infants and children: A one-year prospective audit","volume":"8","author":"Verma","year":"2014","journal-title":"Anesth Essays Res"},{"key":"R11-20250513","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1097\/ALN.0000000000000709","article-title":"General Anesthesia compared to Spinal Anesthesia (GAS) Consortium. Apnea after awake regional and general anesthesia in infants: The general anesthesia compared to spinal anesthesia study\u2014Comparing apnea and neurodevelopmental outcomes, A randomized controlled trial","volume":"123","author":"Davidson","year":"2015","journal-title":"Anesthesiology"},{"key":"R12-20250513","doi-asserted-by":"crossref","first-page":"627","DOI":"10.4103\/aer.AER_246_16","article-title":"Age-based local anesthetic dosing in pediatric spinal anesthesia: Evaluation of a new formula \u2013A pilot study in Indian patients","volume":"11","author":"Parthasarathy","year":"2017","journal-title":"Anesth Essays Res"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_696_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:43:53Z","timestamp":1787773433000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_696_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":12,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_696_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2025-03-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}