{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:27:42Z","timestamp":1787840862676,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>An inadequate apical seal stands out as a primary cause of disappointment in surgical endodontic procedures. Therefore, the choice of root-end filling material should aim to prevent the leakage of potential contaminants into the periapical tissue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To evaluate and compare microleakage of chitosan nano hydrogel-incorporated mineral trioxide aggregate (MTA) and glass ionomer cement (GIC) when used as a retrograde filling material.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Sixty single-rooted premolars were decoronated at cemento enamel junction (CEJ), and root canals were prepared and obturated, with the coronal part sealed with a composite. The dye absorption was measured by an automatic spectrophotometer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The results showed that the MTA + chitosan group had less microleakage values compared to the MTA group but was not statistically significant and GIC + chitosan had less microleakage values compared to the GIC group and was statistically significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Chitosan-incorporated MTA and chitosan-incorporated GIC can be considered as retrograde filling material; however, further\n                      <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                      research and long-term clinical studies are required.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_747_24","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T05:00:28Z","timestamp":1732510828000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["To Evaluate and Compare the Microleakage of Chitosan Nano Hydrogel-Incorporated MTA and Glass Ionomer Cements When used as a Retrograde Filling Material"],"prefix":"10.4103","author":[{"given":"Vinaykumar G.","family":"Suryavanshi","sequence":"first","affiliation":[{"name":"Govt Medical College, Sindhudurg, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi K.","family":"Tale","sequence":"additional","affiliation":[{"name":"Government Medical College (GMC), Sindhudurg, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivekanand D.","family":"Kolvekar","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Basveshwar Medical College and Hospital, Chitrdurga, Karanataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashmi","family":"Chordiya","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Saraswati Dhanvantari Dental College, Parbhani, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P S","family":"Amal","sequence":"additional","affiliation":[{"name":"Department of Cons and Endo, Royal Dental College, Chalissery Palakkad, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Abijeet","sequence":"additional","affiliation":[{"name":"Dentistry, White Pearl Dental Clinic, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"key":"R1-20250114","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s12903-020-1025-9","article-title":"Spectrophotometric analysis evaluating apical microleakage in retrograde filling using GIC, MTA and biodentine: An in-vitro study","volume":"20","author":"Nepal","year":"2020","journal-title":"BMC Oral Health"},{"key":"R2-20250114","article-title":"Comparison of the root end sealing ability of four different retrograde filling materials in teeth with root apices resected at different angles-An invitro study","volume":"10","author":"Jain","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"R3-20250114","doi-asserted-by":"crossref","first-page":"164","DOI":"10.4103\/tdj.tdj_26_17","article-title":"Effect of addition of chitosan on water sorption, solubility and micro hardness of glass ionomer cement","volume":"14","author":"Elbahrawya","year":"2017","journal-title":"Tanta Dent J"},{"key":"R4-20250114","first-page":"12","article-title":"Root end filling materials-A review","volume":"5","author":"Vasudev","year":"2003","journal-title":"Endodontology"},{"key":"R5-20250114","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jdent.2009.09.004","article-title":"Clinical and SEM assessment of ART high-viscosity glass-ionomer sealants after 8-13 years in 4 teeth","volume":"38","author":"Frencken","year":"2010","journal-title":"J Dent"},{"key":"R6-20250114","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.joen.2007.09.007","article-title":"Proroot MTA, MTA-angelus and IRM used to repair largefurcation perforations: Sealability study","volume":"34","author":"Hashem","year":"2008","journal-title":"J Endod"},{"key":"R7-20250114","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0939-6411(03)00161-9","article-title":"Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications","volume":"57","author":"Berger","year":"2004","journal-title":"Eur J Pharm Biopharm"},{"key":"R8-20250114","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.dental.2007.04.007","article-title":"Mineral trioxide aggregate material use in endodontic treatment: A review of the literature","volume":"24","author":"Roberts","year":"2008","journal-title":"Dent Mater"},{"key":"R9-20250114","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1600-9657.2006.00456.x","article-title":"Mineral trioxide aggregate as a root canal filling material in re implanted teeth","volume":"23","author":"Panzarini","year":"2007","journal-title":"Microscopic analysis in monkeys. Dent Traumatol"},{"key":"R10-20250114","doi-asserted-by":"crossref","first-page":"e18","DOI":"10.1016\/j.tripleo.2011.04.028","article-title":"Surgical endodontic management of an invasive cervical resorption class 4 with mineral trioxide aggregate: A 6-year follow-up","volume":"112","author":"Fernandez","year":"2011","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_747_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:30:46Z","timestamp":1787837446000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_747_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,19]]},"references-count":10,"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_747_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,19]]},"assertion":[{"value":"2024-06-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}