{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:33:08Z","timestamp":1787070788513,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>\n                    Primarily affecting individuals with compromised immune systems, invasive aspergillosis is a severe fungal infection that originates in the lungs and spreads to vital organs. Usually, treatment results in death. We present a 44-year-old man hospitalized to the ICU complaining of fever, coughing, bodily aches, and respiratory trouble. Found to have secondary\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    infection and allergic bronchopulmonary aspergillosis, he needed ventilatory assistance. He was unconscious even on antifungal treatment and an intercostal drainage catheter. An arachnoid cyst, as seen on CT scans, indicated central nervous system involvement. This instance emphasizes the need for early diagnosis and intensive therapy in stopping the rapid advancement of illness in high-risk individuals.\n                  <\/jats:p>","DOI":"10.4103\/jpbs.jpbs_792_25","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T17:01:13Z","timestamp":1755190873000},"page":"S2833-S2835","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Invasive Aspergillosis with Secondary Bacterial Infection with E. Coli: A Case Report"],"prefix":"10.4103","volume":"17","author":[{"given":"Maga","family":"Rani","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecological Nursing, Sree Abirami College of Nursing, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Sarala","sequence":"additional","affiliation":[{"name":"Medical Surgical Nursing Department, Sree Abirami College of Nursing, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"R1-20250930","doi-asserted-by":"crossref","first-page":"239","DOI":"10.3390\/brainsci13020239","article-title":"Case report: An intracranial aspergillus infection with cyst formation","volume":"13","author":"Pei","year":"2023","journal-title":"Brain Sci"},{"key":"R2-20250930","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1093\/cid\/cir179","article-title":"High-frequency triazole resistance found In nonculturable Aspergillus fumigatus from lungs of patients with chronic fungal disease","volume":"52","author":"Denning","year":"2011","journal-title":"Clin Infect Dis"},{"key":"R3-20250930","doi-asserted-by":"crossref","first-page":"e00140","DOI":"10.1128\/CMR.00140-18","article-title":"Aspergillus fumigatus and aspergillosis in 2019","volume":"33","author":"Latg\u00e9","year":"2019","journal-title":"Clin Microbiol Rev"},{"key":"R4-20250930","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1007\/s00134-003-1778-z","article-title":"Immunoparalysis as a cause of invasive aspergillosis?","volume":"29","author":"Hartemink","year":"2003","journal-title":"Intensive Care Med"},{"key":"R6-20250930","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1148\/radiographics.21.4.g01jl03825","article-title":"Spectrum of pulmonary aspergillosis: Histologic, clinical, and radiologic findings","volume":"21","author":"Franquet","year":"2001","journal-title":"Radiographics"},{"key":"R7-20250930","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3390\/jof5030055","article-title":"Invasive aspergillosis by Aspergillus flavus: Epidemiology, diagnosis, antifungal resistance, and management","volume":"5","author":"Rudramurthy","year":"2019","journal-title":"J Fungi"},{"key":"R8-20250930","first-page":"11","article-title":"Differentiating pathogenic bacteria through biochemical markers: A study for clinical applications","volume":"1","author":"Ravi","year":"2025","journal-title":"Oral Sphere J Dent Health Sci"},{"key":"R9-20250930","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/s15010-008-7375-x","article-title":"Therapeutic outcome and prognostic factors of invasive aspergillosis in an infectious disease department: A review of 34 cases","volume":"36","author":"Gallien","year":"2008","journal-title":"Infection"},{"key":"R10-20250930","doi-asserted-by":"crossref","first-page":"e0186422","DOI":"10.1371\/journal.pone.0186422","article-title":"Clinical outcome and prognostic factors associated with invasive pulmonary aspergillosis: An 11-year follow-up report from Taiwan","volume":"12","author":"Sun","year":"2017","journal-title":"PloS One"},{"key":"R11-20250930","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1086\/592255","article-title":"Factors associated with overall and attributable mortality in invasive aspergillosis","volume":"47","author":"Nivoix","year":"2008","journal-title":"Clin Infect Dis"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_792_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:36:36Z","timestamp":1787067396000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_792_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":10,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_792_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,14]]},"assertion":[{"value":"2025-04-05","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}