{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T01:59:11Z","timestamp":1790474351039,"version":"4.1.0"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To assess clinically and histologically the efficacy of TheraCal LC and Biodentine as Direct Pulp Capping agents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Method:<\/jats:title>\n                    <jats:p>Sixty caries-free maxillary first premolar teeth which were scheduled for orthodontic extraction were selected for the study and were divided equally into Group 1 (Theracal LC) and Group 2 (Biodentine). Thermal and electric pulp testing was performed on the teeth to assess pulp vitality followed by tooth preparation to expose pulp horns under local anesthesia. After achieving hemostasis, the direct pulp capping agent was placed and composite restoration was done. All the teeth were evaluated and compared in terms of clinical and histological findings after 6 weeks. The statistical analysis used was the Kruskal-Wallis test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Teeth with Theracal LC showed no sensitivity to heat, cold, or percussion, whereas sensitivity to heat, cold, or percussion was noted with Biodentine. Histological evaluation revealed that TheraCal LC has higher efficiency in complete dentin bridge formation, had maximum dentin thickness, and showed minimal or no pulpal disorganization and pulpal inflammation as compared to Biodentine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>TheraCal LC proves to be a promising future as a direct pulp capping agent.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_805_23","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T09:20:20Z","timestamp":1713259220000},"page":"S1420-S1422","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy of TheraCal LC and Biodentine as Direct Pulp Capping Agents - An Clinico-Histological Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Shalini","family":"Singh","sequence":"first","affiliation":[{"name":"PHD Scholar, Department of Conservative Dentistry and Endodontics, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poonam","family":"Joshi","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Conservative Dentistry and Endodontics, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reshma","family":"Rajasekhar","sequence":"additional","affiliation":[{"name":"PHD Scholar, Department of Conservative Dentistry and Endodontics, Narsinhbhai Patel Dental College and Hospital, Sankalchand Patel University, Visnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumant V.","family":"Saoji","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Prosthodontics, CSMSS Dental College and Hospital Kanchanwadi, Sambhajinagar, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Richhawal","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Conservative Dentistry and Endodontics, YMT Dental College and Hospital, Kharghar, Navi Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasleen K.","family":"Punia","sequence":"additional","affiliation":[{"name":"Dental Surgeon, Krishna Dental Clinic, Deoria, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"333","DOI":"10.17796\/jcpd.38.4.m585322121536q71","article-title":"Primate pulpal healing after exposure and TheraCal application","volume":"38","author":"Cannon","year":"2014","journal-title":"J Clin Pediatr Dent"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1055\/s-0038-1672009","article-title":"A confocal laser scanning microscopic study evaluating the sealing ability of mineral trioxide aggregate, biodentine and a new pulp capping agent-TheraCal","volume":"3","author":"Makkar","year":"2015","journal-title":"Dent J Adv Stud"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.tripleo.2008.06.006","article-title":"A comparative study of histologic response to different pulp capping materials and a novel endodontic cement","volume":"106","author":"Asgary","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R4-20240829","first-page":"85","article-title":"Clinical and histological evaluation of white ProRoot MTA in direct pulp capping","volume":"19","author":"Iwamoto","year":"2006","journal-title":"Am J Dent"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1046\/j.1365-2591.2003.00652.x","article-title":"Mineral trioxide aggregate (MTA) and calcium hydroxide as pulp-capping agents in human teeth: A preliminary report","volume":"36","author":"Aeinehchi","year":"2002","journal-title":"Int Endod J"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1016\/j.joen.2014.06.018","article-title":"Hydration of biodentine, theracal LC, and a prototype tricalcium silicate-based dentin replacement material after pulp capping in entire tooth cultures","volume":"40","author":"Camilleri","year":"2014","journal-title":"J Endod"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.dental.2014.03.012","article-title":"Hydration characteristics of Biodentine and Theracal used as pulp capping materials","volume":"30","author":"Camilleri","year":"2014","journal-title":"Dent Mater"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_805_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:33:02Z","timestamp":1787769182000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_805_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":7,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_805_23","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2023-08-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-11","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}