{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:46:51Z","timestamp":1787071611520,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      The efficacy of clear aligner therapy (CAT) in the management of malocclusion is largely dependent on patient compliance, especially the proper use of aligners. Objective: The present study investigated the influence of an artificial intelligence (AI) mobile application (StrojCHECK\n                      <jats:sup>\u00ae<\/jats:sup>\n                      ) on patient participation and follow-through with CAT treatment regimens.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Fifty-five patients (33 women, 22 men) aged 12-68 years were tracked pre- and post-an update to the app\u2019s AI system with features such as decision tree algorithms, individualized feedback, and real-time alerting for patients and clinicians.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Our findings indicated increased patient app engagement scores from 4.2 to 7.3 and improved clinical aligner tracking adherence from 85% to 92%. Gender-based analysis showed a highly significant decrease in non-compliance among women participants (from 10% to 5%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05), whereas the compliance of males did not change.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The investigation emphasizes the crucial role of collecting behavioral data and individualized feedback in improving the outcome of treatments. The adoption of AI technology in digital healthcare solutions has vast potential to increase patient compliance and maximize orthodontic treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_815_25","type":"journal-article","created":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T17:00:40Z","timestamp":1758733240000},"page":"S2671-S2673","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Enhancing Clear Aligners Therapy with Artificial Intelligence and Technology"],"prefix":"10.4103","volume":"17","author":[{"given":"Radhika","family":"Nair","sequence":"first","affiliation":[{"name":"Clinical Project Manager, InBrace, Irvine, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,9,24]]},"reference":[{"key":"R1-20250930","first-page":"97","article-title":"Prevalence of malocclusion and orthodontic treatment need in the United States: Estimates from the NHANES III survey","volume":"13","author":"Proffit","year":"1998","journal-title":"Int J Adult Orthodon Orthognath Surg"},{"key":"R2-20250930","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12903-018-0695-z","article-title":"A comparison of treatment effectiveness between clear aligner and fixed appliance therapies","volume":"19","author":"Ke","year":"2019","journal-title":"BMC Oral Health"},{"key":"R3-20250930","doi-asserted-by":"crossref","first-page":"881","DOI":"10.2319\/061614-436.1","article-title":"Efficacy of clear aligners in controlling orthodontic tooth movement: A systematic review","volume":"85","author":"Rossini","year":"2015","journal-title":"Angle Orthod"},{"key":"R5-20250930","doi-asserted-by":"crossref","first-page":"7459","DOI":"10.3390\/ijerph18147459","article-title":"Tele-monitoring system for chronic diseases management: Requirements and architecture","volume":"18","author":"Mucchi","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"R6-20250930","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.3390\/ijerph18052636","article-title":"Digital health transition in rheumatology: A qualitative study","volume":"18","author":"Muehlensiepen","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"R7-20250930","doi-asserted-by":"crossref","first-page":"726","DOI":"10.3390\/medicina57070726","article-title":"The role of telemedicine in extending and enhancing medical management of the patient with chronic obstructive pulmonary disease","volume":"57","author":"Donner","year":"2021","journal-title":"Medicina"},{"key":"R8-20250930","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3390\/neurolint13010003","article-title":"Telemedicine during the coronavirus disease (COVID-19) pandemic: A multiple sclerosis (MS) outpatients service perspective","volume":"13","author":"Corea","year":"2021","journal-title":"Neurol Int"},{"key":"R9-20250930","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.3390\/healthcare9121695","article-title":"Artificial intelligence in orthodontic smart application for treatment coaching and its impact on clinical performance of patients monitored with AI-TeleHealth system","volume":"9","author":"Thurzo","year":"2021","journal-title":"Healthcare (Basel)"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_815_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:49:31Z","timestamp":1787068171000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_815_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":8,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_815_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"2025-04-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-07","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}