{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T19:02:53Z","timestamp":1788030173546,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:00:00Z","timestamp":1731456000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>\n                    The female reproductive system relies on the intact uterine adnexa and the hypothalamic-pituitary-ovarian axis. An imbalance can lead to pathogenesis. PCOS is characterized by ovarian cysts, hyperandrogenism, and irregular ovulation. Over time, it can lead to symptoms such as changes in menstruation, obesity, infertility, depression, and increased risk of diabetes, cardiovascular disease, and endometrial cancer. In Ayurveda, PCOS is a condition affecting\n                    <jats:italic toggle=\"yes\">Rasa<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Rakta<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">Medas<\/jats:italic>\n                    , the three\n                    <jats:italic toggle=\"yes\">Dhatus<\/jats:italic>\n                    .\n                    <jats:italic toggle=\"yes\">Rakta<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Rasa<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">Artavavaha<\/jats:italic>\n                    are the\n                    <jats:italic toggle=\"yes\">Srotas<\/jats:italic>\n                    that are implicated in this illness. Symptoms that may appear include\n                    <jats:italic toggle=\"yes\">Anartava<\/jats:italic>\n                    (amenorrhea),\n                    <jats:italic toggle=\"yes\">Vandhyatwa<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Pushpagni<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">Abeeja Rutuchakra<\/jats:italic>\n                    (an ovular hemorrhage). A 23-year-old woman presented at the outpatient department with complaints of irregular menstruation and rapid weight gain. An ultrasound revealed left-sided polycystic ovary syndrome (PCOS). Palliative treatments such as\n                    <jats:italic toggle=\"yes\">Kaklarakshak Yog<\/jats:italic>\n                    ,\n                    <jats:italic toggle=\"yes\">Trikatu<\/jats:italic>\n                    , and\n                    <jats:italic toggle=\"yes\">Triphala Churna<\/jats:italic>\n                    were administered for 2 months. The patient experienced a significant reduction in symptoms and a return to a normal menstrual cycle within two months.\n                  <\/jats:p>","DOI":"10.4103\/jpbs.jpbs_819_24","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T07:04:16Z","timestamp":1731481456000},"page":"S4179-S4181","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Ayurvedic Approaches to Holistic Management of Polycystic Ovary Syndrome (PCOS)"],"prefix":"10.4103","volume":"16","author":[{"given":"Ashvini D.","family":"Pardhekar","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Kayachikitsa, Mahatma Gandhi Ayurved College, Hospital and Research Centre, Salod (H), Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (M), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Waskar","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Kayachikitsa, Mahatma Gandhi Ayurved College, Hospital and Research Centre, Salod (H), Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (M), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhilash","family":"Pardhekar","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Rachana Sharir, Govindrao Vanjari Ayurvedic Hospital & Research Center, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayuri","family":"Deshpande","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Kayachikitsa, Mahatma Gandhi Ayurved College, Hospital and Research Centre, Salod (H), Datta Meghe Institute of Higher Education and Research (Deemed to be University), Sawangi (M), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,13]]},"reference":[{"key":"R3-20241227","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.jfma.2021.08.015","article-title":"Mechanism of quercetin on the improvement of ovulation disorder and regulation of ovarian CNP\/NPR2 in PCOS model rats","volume":"121","author":"Zheng","year":"2022","journal-title":"J Formos Med Assoc"},{"key":"R4-20241227","first-page":"1","article-title":"Clinical evaluation of Trikatu &Kumari as hypolipidemic drug","volume":"2","author":"Singh","year":"2017","journal-title":"Int J Ayurveda and Med Sci"},{"key":"R5-20241227","first-page":"80","article-title":"A case study on Ayurvedic management in PCOS","volume":"9","author":"Mole","year":"2021","journal-title":"Int J Ayurveda Pharm 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pathway","volume":"24","author":"Cai","year":"2020","journal-title":"Anim Cells Syst (Seoul)"},{"key":"R9-20241227","first-page":"698","article-title":"An Ayurvedic Management of Irregular Menstruation with Special Reference to Pcos-A Case Study","volume":"9","author":"Pawar","year":"2020","journal-title":"WJPS"},{"key":"R10-20241227","first-page":"1810","article-title":"Case report on Ayurveda management of polycystic ovarian syndrome (PCOS)","volume":"9","author":"Ghaywate","year":"2020","journal-title":"World J Pharm Pharm Sci"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_819_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:25:00Z","timestamp":1787837100000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_819_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,13]]},"references-count":8,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_819_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,13]]},"assertion":[{"value":"2024-07-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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