{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:19:49Z","timestamp":1787771989523,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Introduction:<\/jats:title>\n HSP is arguably the most thoroughly studied self-antigens connected to Cardio Vascular Diseases (CVD) and periodontal disease. Hence, the major goal of this analysis was to determine the amount of HSP60 in patients\u2019 Chronic Periodontitis (CP) patients\u2019 serum.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n The current investigation involved 100 patients in all. Based on the patients\u2019 periodontal and cardiovascular health, the patients were divided. The patients were made aware that this research had no direct bearing on disease treatment or cure.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n In contrast to periodontal disease, which had a mean serum HSP60 of 59.94 ng\/dl, CVD had a mean serum HSP60 of 85.98 ng\/dl. When compared to periodontal disease, the CVD increased significantly (\n P<\/jats:italic>\n < 0.05, 0.03).\n <\/jats:p>\n <\/jats:sec>\n \n Discussion and Conclusion:<\/jats:title>\n We emphasize the function of HSP60 in the pathophysiology of individuals with chronic periodontitis based on the findings of the current investigation. Serum HSP60 concentrations can serve as a biomarker for periodontal inflammation. More longitudinal and interventional research with a larger sample size is required to validate the present findings. In periodontal therapies, targeting HSP60 may enhance results.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_829_23","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T15:11:23Z","timestamp":1709219483000},"page":"S498-S500","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the Circulatory Levels of Heat Shock Protein 60 Levels in Periodontitis and Cardiovascular Disease Patients"],"prefix":"10.4103","volume":"16","author":[{"given":"Rakshit K.","family":"Dalal","sequence":"first","affiliation":[{"name":"Private Practitioner, Dalal Dental Clinic, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manpreet","family":"Kaur","sequence":"additional","affiliation":[{"name":"Certified Dental Assistant, Cedarview Dentistry Clinic, Nepean, ON K2J OV2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Komal","family":"Khatri","sequence":"additional","affiliation":[{"name":"Private Practitioner, Nusmile Dentistry and Orthodontics, Kalol, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Foram","family":"Patel","sequence":"additional","affiliation":[{"name":"Georgia Southern University, Statesboro, GA, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heena","family":"Shaikh","sequence":"additional","affiliation":[{"name":"Healthcare Leadership, Mississauga, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arifa","family":"Bakerywala","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Tufts University School of Dental Medicine, Massachusetts, United States of America"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,2,29]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"577","DOI":"10.3109\/10520295.2014.918280","article-title":"A study of C-reactive protein, lipid metabolism and peripheral blood to identify a link between periodontitis and cardiovascular disease","volume":"89","author":"Sharma","year":"2014","journal-title":"Biotech Histochem"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3390\/pathogens3010187","article-title":"Heat shock proteins: Intestinal gatekeepers that are influenced by dietary components and the gut microbiota","volume":"3","author":"Liu","year":"2014","journal-title":"Pathogens"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1600-0757.2012.00450.x","article-title":"Periodontitis: A host-mediated disruption of microbial homeostasis. 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