{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:29:53Z","timestamp":1787840993090,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Obstructive sleep apnea (OSA) and chronic periodontitis share inflammatory pathways, potentially exacerbating periodontal disease with increased severity of OSA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted involving 500 patients with sleep disorders. The prevalence and severity of OSA were determined using polysomnography and the Apnoea-Hypopnea Index, categorized into three stages, and associated comorbidities were recorded from medical records. The periodontal status was evaluated using clinical parameters such as the Oral Hygiene Index, Gingival Index, probing pocket depth, clinical attachment level, and gingival recession.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Patients with periodontal disease (OSA) had varying severity levels, with severe OSA (78.4%) causing more severe periodontal disease compared to moderate (35.4%) and mild (20.3%) patients. Patients with moderate and severe OSA stages showed significantly higher prevalence of comorbidities like hypertension (100%), coronary heart disease (90.5%), diabetes mellitus (71.6%), and obesity (51.4%) with statistically significant associations found (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Patients also exhibit parafunctional habits, including smoking (43.2%) and mouth breathing (60.8%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A significant association between mild OSA, increasing with age and males, and chronic periodontal disease, with severe OSA exhibiting greater periodontal destruction was found.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_844_24","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T07:00:27Z","timestamp":1733468427000},"page":"S3367-S3369","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Determination of the Association between Obstructive Sleep Apnea and Chronic Periodontal Disease: A Cross-Sectional Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Kumari","family":"Pallavi","sequence":"first","affiliation":[{"name":"Department of Periodontology, Rama Dental College Hospital and Research Centre, Rama University, Kanpur, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.J. Janardhana","family":"Amaranath","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Rama Dental College Hospital and Research Centre, Rama University, Kanpur, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelam","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Rama Dental College Hospital and Research Centre, Rama University, Kanpur, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koushik","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Rama Dental College Hospital and Research Centre, Rama University, Kanpur, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arindam","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Rama Dental College Hospital and Research Centre, Rama University, Kanpur, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Katiyar","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Rama Dental College Hospital and Research Centre, Rama University, Kanpur, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,5]]},"reference":[{"key":"R1-20241227","first-page":"861","article-title":"The association between obstructive sleep apnea and periodontal disease:A systematic review and meta-analysis","volume":"89","author":"Latorre","year":"2018","journal-title":"J Periodontol"},{"key":"R2-20241227","first-page":"389","article-title":"Severe periodontitis and obstructive sleep apnea:A cross-sectional study","volume":"50","author":"Jimenez","year":"2023","journal-title":"J Clin Periodontol"},{"key":"R3-20241227","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.smrv.2013.01.003","article-title":"Untreated obstructive sleep apnea and the risk for serious long-term adverse outcomes:A systematic review","volume":"18","author":"Kendzerska","year":"2014","journal-title":"Sleep Med Rev"},{"key":"R4-20241227","first-page":"1014","article-title":"Periodontitis and obstructive sleep apnea:A review","volume":"59","author":"Chen","year":"2023","journal-title":"Sleep Med Rev"},{"key":"R5-20241227","first-page":"165","article-title":"Periodontitis and obstructive sleep apnea in adults:A systematic review and meta-analysis","volume":"94","author":"Sanders","year":"2015","journal-title":"J Dent Res"},{"key":"R6-20241227","first-page":"405","article-title":"The association between obstructive sleep apnea and hematocrit and hemoglobin levels:A meta-analysis","volume":"18","author":"Deng","year":"2014","journal-title":"Sleep Med Rev"},{"key":"R7-20241227","first-page":"56","article-title":"Obstructive sleep apnea and comorbidities:A cross-sectional study in older adults","volume":"15","author":"Silva","year":"2022","journal-title":"Sleep Sci"},{"key":"R8-20241227","first-page":"52","article-title":"Gender differences in the prevalence and severity of obstructive sleep apnea:A population-based study","volume":"97","author":"Kim","year":"2023","journal-title":"Sleep Med"},{"key":"R9-20241227","first-page":"16","article-title":"Cardiovascular comorbidities in obstructive sleep apnea:A review","volume":"19","author":"Ivanovski","year":"2023","journal-title":"Curr Cardiol Rev"},{"key":"R10-20241227","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4081\/mrm.2019.10","article-title":"Obstructive sleep apnea and comorbidities:A dangerous liaison","volume":"14","author":"Bonsignore","year":"2019","journal-title":"Multidiscip Respir Med"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_844_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:39:24Z","timestamp":1787837964000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_844_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":10,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_844_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-07-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-03","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}