{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:20:55Z","timestamp":1787764855100,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To determine the therapeutic effect and efficacy of oral colchicine tablet and intralesional injection of hyaluronidase with and without ultrasound therapy in the clinical course of oral submucous fibrosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      This comparative study involving 45 human participants was divided into three equal groups. The participants in group 1 received oral colchicine and intralesional hyaluronidase. The participants in group 2 received oral colchicine, intralesional hyaluronidase, and ultrasound therapy. The group 3 participants were treated with intralesional dexamethasone and hyaluronidase. Intergroup assessments were done using repeated measures of ANOVA test, where\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value of &lt;0.05 was considered as statistically significant difference.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Group 2 patients had maximum improvement with respect to all the parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Therapeutic ultrasound can be given effectively as an adjunct therapy along with conventional therapy in OSMF patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_879_23","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T05:05:12Z","timestamp":1700197512000},"page":"S586-S588","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of Oral Colchicine and Intralesional Hyaluronidase with and without Ultrasound Therapy in the Management of Oral Submucous Fibrosis\u2014A Comparative Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Malabika","family":"Shil","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Radiologist, Nidaan Diagnostic Centre, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poulami","family":"Goswami","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Mithila Minority Dental College and Hospital, Darbhanga, Bihar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trupti Vijay","family":"Gaikwad","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gargi","family":"Jadaun","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Pacific Dental College and Hospital, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Sridhar","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Priyadarshini Dental College and Hospital, Pandur, Thiruvallur, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basudhara","family":"Bandyopadhyay","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, Intern, Kalinga Institute of Dental Sciences, KIIT Deemed to be University, Patia, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratik","family":"Surana","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, Maitri College of Dentistry and Research Centre, Durg, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,11,7]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"349","DOI":"10.4103\/jiaomr.jiaomr_142_18","article-title":"Efficacy of therapeutic ultrasound with soft tissue mobilization in patients of oral submucous fibrosis","volume":"30","author":"Tyagi","year":"2018","journal-title":"J Indian Acad Oral Med Radiol"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jobcr.2013.10.005","article-title":"Prevalence of oral submucous fibrosis among habitual gutkha and areca nut chewers in Moradabad district","volume":"4","author":"Nigam","year":"2014","journal-title":"J Oral Biol Craniofac Res"},{"issue":"Suppl 2","key":"R3-20240829","doi-asserted-by":"crossref","first-page":"S837","DOI":"10.4103\/jpbs.jpbs_273_23","article-title":"Role of physiotherapy in HPV proven cases of oral submucous fibrosis","volume":"15","author":"Syed","year":"2023","journal-title":"J Pharm Bioallied Sci"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"13728","DOI":"10.14260\/jemds\/2015\/1959","article-title":"Recent concepts of etiopathogenesis and management of oral submucous fibrosis: A review of literature","volume":"4","author":"Singh","year":"2015","journal-title":"J Evol Med Dent Sci"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"50","DOI":"10.4103\/njms.NJMS_5_17","article-title":"Efficacy of oral colchicine with intralesional hyaluronidase or triamcinolone acetonide in the Grade II oral submucous fibrosis","volume":"8","author":"Daga","year":"2017","journal-title":"Natl J Maxillofac Surg"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"623","DOI":"10.7863\/jum.2012.31.4.623","article-title":"Overview of therapeutic ultrasound applications and safety considerations","volume":"31","author":"Miller","year":"2012","journal-title":"J Ultrasound Med"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.oraloncology.2011.10.011","article-title":"Proposed clinical classification for oral submucous fibrosis","volume":"48","author":"More","year":"2012","journal-title":"Oral Oncol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_879_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:48:22Z","timestamp":1787762902000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_879_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,7]]},"references-count":7,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_879_23","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,7]]},"assertion":[{"value":"2023-09-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}