{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:29:49Z","timestamp":1787761789954,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Peripheral Arterial Disease (PAD) significantly impairs functional capacity and quality of life (QoL) due to reduced lower limb perfusion. This study evaluates the effectiveness of a nurse-led intervention program incorporating dietary counseling, exercise, and education on functional capacity and QoL in PAD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A pretest\/posttest-controlled design was employed with 30 participants (15 experimental, 15 control) recruited from KG Hospital, Coimbatore, India. The intervention included nutritional supplementation, home-based walking, Buerger Allen exercises, and educational sessions over six months. Outcomes were assessed using the Ankle\u2013Brachial Index (ABI), 6-Minute Walk Test (6MWT), Walking Impairment Questionnaire (WIQ), and VascuQoL-25 at baseline, three months, and six months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The experimental group showed significant improvements in ABI (0.84 vs. 0.65,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001), 6MWT distance (278.87 vs. 186.93 meters,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001), and WIQ scores (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01) at six months compared to controls. Biochemical markers, including fasting blood sugar (FBS) and Hemoglobin A1c (HbA1c), also improved significantly. No adverse events were reported, indicating the intervention\u2018s safety.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>These findings suggest that nurse-led interventions are effective in enhancing functional capacity and metabolic health in PAD patients, supporting their integration into clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_889_25","type":"journal-article","created":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T16:00:27Z","timestamp":1753286427000},"page":"72-74","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Impact of a Nurse-Led Lifestyle Intervention on Functional Capacity and Quality of Life in Peripheral Arterial Disease: A Controlled Study"],"prefix":"10.4103","volume":"17","author":[{"given":"Aruchamy","family":"Santhipriya","sequence":"first","affiliation":[{"name":"Ph.D (Nursing) Scholar, Department of Medical Surgical Nursing, Vinayaka Mission\u2019s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkatesan","family":"Selvanayaki","sequence":"additional","affiliation":[{"name":"Department of Obstetric and Gynaecological Nursing, Vinayaka Mission\u2019s Annapoorna College of Nursing, Vinayaka Mission\u2019s Research Foundation, (Deemed to be University), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,7,23]]},"reference":[{"key":"R1-20260422","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1161\/CIRCRESAHA.116.303849","article-title":"Epidemiology of peripheral artery disease","volume":"116","author":"Criqui","year":"2015","journal-title":"Circ Res"},{"key":"R2-20260422","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/S0140-6736(13)61249-0","article-title":"Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: A systematic review and analysis","volume":"382","author":"Fowkes","year":"2013","journal-title":"Lancet"},{"key":"R3-20260422","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.atherosclerosis.2018.05.033","article-title":"Update on peripheral artery disease: Epidemiology and evidence-based facts","volume":"275","author":"Shu","year":"2018","journal-title":"Atherosclerosis"},{"key":"R4-20260422","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/S0741-5214(97)70045-4","article-title":"Recommended standards for reports dealing with lower extremity ischemia: revised version","volume":"26","author":"Rutherford","year":"1997","journal-title":"J Vasc Surg"},{"key":"R5-20260422","first-page":"2514","article-title":"The effectiveness of nurse-led care in general practice on clinical outcomes in adults with type 2 diabetes","volume":"10","author":"Parker","year":"2012","journal-title":"JBI Libr Syst Rev"},{"key":"R6-20260422","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0002-9149(00)01367-9","article-title":"Effects of exercise rehabilitation on endothelial reactivity in older patients with peripheral arterial disease","volume":"87","author":"Brendle","year":"2001","journal-title":"Am J Cardiol"},{"key":"R7-20260422","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1001\/jama.292.4.453","article-title":"Functional decline in peripheral arterial disease: associations with the ankle brachial index and leg symptoms","volume":"292","author":"McDermott","year":"2004","journal-title":"JAMA"},{"key":"R8-20260422","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1186\/s12955-017-0760-3","article-title":"Validation of the Vascular quality of life questionnaire - 6 for clinical use in patients with lower limb peripheral arterial disease","volume":"15","author":"Larsen","year":"2017","journal-title":"Health and quality of life outcomes,"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_889_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:05:44Z","timestamp":1787760344000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_889_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_889_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"2025-02-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}