{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:20:58Z","timestamp":1787840458269,"version":"build-2784847793"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To compare the effect of topical application of Argyreia speciosa gel and noneugenol periodontal dressing on wound healing and pain following periodontal flap surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Periodontal flap surgery is a leading treatment for managing periodontal pockets in chronic periodontitis. Healing plays a crucial role in restoring periodontal tissue integrity. The necessity of postprocedure periodontal dressing is questioned due to evidence suggesting that thorough cleanliness alone can promote complete healing. Argyreia speciosa, a revered medicinal plant, known for its anti-inflammatory, antimicrobial, and analgesic properties.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>\n                      Periodontal flap surgery was performed in 20 patients (40 sites). After flap surgery, patients were randomly assigned to Argyreia speciosa gel group or COE-PAK group. Early Healing Score (EHS) after 1\n                      <jats:sup>st<\/jats:sup>\n                      week and Healing Index (HI) and Visual Analog Scale (VAS) scoring was done after 1\n                      <jats:sup>st<\/jats:sup>\n                      and 2\n                      <jats:sup>nd<\/jats:sup>\n                      week.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The results indicated that the Argyreia speciosa gel group experienced significantly less pain, as measured by the VAS (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.014), and demonstrated better wound healing, assessed through the EHS (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.025) and HI (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.014), compared to the periodontal dressing group during the first week. These differences were statistically significant. However, by the second week, the differences in HI and VAS scores between the Argyreia speciosa gel group and the periodontal dressing group were not statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Argyreia speciosa gel exhibits efficacy superior to noneugenol periodontal dressing in promoting wound healing and reducing pain perception at first week, suggesting its potential as an alternative to noneugenol periodontal dressing after periodontal flap surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_895_24","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:02:48Z","timestamp":1750208568000},"page":"S1911-S1915","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating the Impact of Argyreia Speciosa Gel versus Noneugenol Periodontal Dressing on Wound Healing and Pain Postperiodontal Flap Surgery: A Split-Mouth Randomized Clinical Trial"],"prefix":"10.4103","volume":"17","author":[{"given":"Saurabh","family":"Patil","sequence":"first","affiliation":[{"name":"Department of Periodontology, SMBT Dental College and Hospital, Sangamner, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaishali Kisan","family":"Lihe","sequence":"additional","affiliation":[{"name":"Department of Periodontology, SMBT Dental College and Hospital, Sangamner, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupali","family":"Borade","sequence":"additional","affiliation":[{"name":"Department of Periodontology, SMBT Dental College and Hospital, Sangamner, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka","family":"Kurdukar","sequence":"additional","affiliation":[{"name":"Department 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