{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:26:37Z","timestamp":1787840797454,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 5","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Children living with perinatal HIV\/AIDS (CLWPHA) have a higher prevalence of dental caries and fungal infections. Caries tooth serves as a niche for Candida colonization and it also impairs oral health-related quality of life. The management of dental caries can eliminate the risk factor for Candida colonization and subsequently can promote their quality of life related to oral health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>\n                      The aim of our study was to determine the effect of dental caries management on the\n                      <jats:italic toggle=\"yes\">Candida albicans<\/jats:italic>\n                      carriage and oral health-related quality of life among CLWPHA under highly active antiretroviral therapy (HAART).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>This pre- and post-experimental study was conducted with 40 students. Candida colonization was assessed from the participant\u2019s saliva samples. OHRQoL of participants was assessed using the Oral Health Impact Profile-14 questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean value of\n                      <jats:italic toggle=\"yes\">Candida albicans<\/jats:italic>\n                      CFUs in saliva after dental caries management was significantly lower compared with before dental caries management. The mean OHIP-14 score after dental caries management was significantly lower compared with the baseline score.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Dental caries management can be effective in reducing the oral Candidal colony count, thereby improving their oral health-related quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_917_24","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T11:05:13Z","timestamp":1738235113000},"page":"S4445-S4447","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Effect of Dental Caries Management on the Candida Albicans Carriage and Oral Health-Related Quality of Life in Children Living With Perinatal HIV\/AIDS Under Antiretroviral Therapy\u2014A Pre- and Post-Experimental Study"],"prefix":"10.4103","volume":"16","author":[{"given":"M. Monica","family":"Gurupriya","sequence":"first","affiliation":[{"name":"Department of Public Health Dentistry, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. Divya","family":"Barathi","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, Mahatma Gandhi Post Graduate Institute of Dental Sciences, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok Viswanath","family":"Nalankilli","sequence":"additional","affiliation":[{"name":"Department of Virology, Government Tirunelveli Medical College and Hospital, Tirunelveli, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Megalaa","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, Mahatma Gandhi Post Graduate Institute of Dental Sciences, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merlin","family":"Jayaraj","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Chettinad Dental College and Research Institute, Chengalpet, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. D. Madan","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Ragas Dental College, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagappan","family":"Nagappan","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Chettinad Dental College and Research Institute, Chengalpet, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"key":"R3-20250130","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1186\/1471-2431-10-85","article-title":"Treatment and disease progression in a birth cohort of vertically HIV-1 infected children in Ukraine","volume":"10","author":"Mahdavi","year":"2010","journal-title":"BMC Pediatr"},{"key":"R5-20250130","first-page":"1107","article-title":"The germ colonization of the oral cavity in small children with the nursing bottle syndrome","volume":"103","author":"Wetzel","year":"1993","journal-title":"Schweiz Monatsschr Zahnmed"},{"key":"R6-20250130","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1046\/j.1365-280X.1999.00242.x","article-title":"Effect of dental treatment and\/or local application of amphotericin B to carious teeth on oral colonization by Candida","volume":"37","author":"Sziegoleit","year":"1999","journal-title":"Med Mycol"},{"key":"R7-20250130","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000351673","article-title":"Changes in Candida spp., Mutans streptococci and lactobacilli following treatment of early childhood caries:A 1-year follow-up","volume":"48","author":"Klinke","year":"2014","journal-title":"Caries Res"},{"key":"R8-20250130","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.tripleo.2009.04.038","article-title":"Reduction of Candida species colonization in the oral cavity of children infected with human immunodeficiency virus after dental treatment","volume":"108","author":"Chagas","year":"2009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R11-20250130","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/j.1600-0528.1997.tb00941.x","article-title":"Derivation and validation of a short-form oral health impact profile","volume":"25","author":"Slade","year":"1997","journal-title":"Community Dent Oral Epidemiol"},{"key":"R12-20250130","first-page":"149","article-title":"Methods of collection of saliva - A review","volume":"3","author":"Priya","year":"2017","journal-title":"Int J Oral Health Dent"},{"key":"R13-20250130","first-page":"27","article-title":"Quantity of candida colonies in saliva:A diagnostic evaluation for oral candidiasis","volume":"20","author":"Zhou","year":"2017","journal-title":"Chin J Dent Res"},{"key":"R14-20250130","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1067\/moe.2002.120804","article-title":"Candida carriage in the oral cavity of human immunodeficiency virus-infected subjects","volume":"93","author":"Campisi","year":"2002","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R15-20250130","doi-asserted-by":"crossref","first-page":"4159","DOI":"10.1128\/JCM.43.8.4159-4162.2005","article-title":"Oral Candida isolates colonizing or infecting human immunodeficiency virus-infected and healthy persons in Mexico","volume":"43","author":"Sanchez-Vargas","year":"2005","journal-title":"J Clin Microbiol"},{"key":"R16-20250130","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1186\/1756-0500-7-478","article-title":"Oral health status and its impact on the quality of life of children and adolescents living with HIV-1","volume":"7","author":"Rovaris","year":"2014","journal-title":"BMC Res Notes"},{"key":"R17-20250130","doi-asserted-by":"crossref","first-page":"e0207262","DOI":"10.1371\/journal.pone.0207262","article-title":"In vitro effects of commercial mouthwashes on several virulence traits of Candida albicans, viridians streptococci and Enterococcus faecalis colonizing the oral cavity","volume":"13","author":"Ardizzoni","year":"2018","journal-title":"PLoS One"},{"key":"R18-20250130","first-page":"258","article-title":"Changes in young children's OHRQoL after dental treatment under general anaesthesia","volume":"22","author":"Gaynor","year":"2012","journal-title":"Int J Paediatr"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_917_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:29:15Z","timestamp":1787837355000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_917_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":13,"journal-issue":{"issue":"Suppl 5","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_917_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-08-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}