{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:36:58Z","timestamp":1787071018657,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:00:00Z","timestamp":1732838400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n The study aimed to evaluate soft tissue changes resulting from orthognathic surgery, specifically LeFort osteotomy, and distraction osteogenesis, in individuals with cleft lip and palate (CLP) suffering from midface hypoplasia. Following PRISMA guidelines, eight papers met inclusion criteria, with six providing quantitative data for meta-analysis. Notably, significant improvements were observed in both hard and soft tissues, particularly with horizontal maxillary advancement. Overall, orthognathic surgery positively influenced soft tissue profiles, especially the combination of LeFort osteotomy and sagittal split osteotomy. Moreover, maxillary distraction osteogenesis demonstrated superior soft tissue changes compared to LeFort I osteotomy alone, suggesting avenues for further research and potential enhancements.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_967_24","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T11:00:15Z","timestamp":1732878015000},"page":"S3096-S3098","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of Soft Tissue Changes after Various Orthognathic Surgeries for Class III Correction of Cleft Lip and Cleft Palate Patients: A Systematic Review and Meta-Analysis"],"prefix":"10.4103","volume":"16","author":[{"given":"B","family":"Kanagasabapathy","sequence":"first","affiliation":[{"name":"Department of Orthodontics, CSI Dental College, Madurai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubham","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, I.T.S Centre for Dental Studies and Research, Muradnagar, Ghaziabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piyush","family":"Dua","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, I.T.S Centre for Dental Studies and Research, Muradnagar, Ghaziabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikil K.","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Awadh Dental College and Hospital, Jamshedpur, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V","family":"Preethi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Sri Ramachandra Dental College, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Monika","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, ACPM Dental College, Dhule, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,29]]},"reference":[{"key":"R1-20241227","first-page":"5","article-title":"Treatment variables affecting facial growth in complete unilateral cleft lip and palate","volume":"24","author":"Ross","year":"1987","journal-title":"Cleft Palate J"},{"key":"R2-20241227","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0266-4356(89)90037-5","article-title":"A retrospective study of the stability of midface osteotomies in cleft lip and palate patients","volume":"27","author":"Adlam","year":"1989","journal-title":"Br J Oral Maxillofac Surg"},{"key":"R3-20241227","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"key":"R4-20241227","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/0889-5406(92)70130-3","article-title":"Soft tissue response to mandibular advancement and genioplasty","volume":"101","author":"Ewing","year":"1992","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"R5-20241227","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1053\/joms.2000.8735","article-title":"Soft tissue profile changes after maxillary advancement with distraction osteogenesis by use of a rigid external distraction device:A 1-year follow-up","volume":"58","author":"Ko","year":"2000","journal-title":"J Oral Maxillofac 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Oral Maxillofac Surg"},{"key":"R9-20241227","doi-asserted-by":"crossref","first-page":"4","DOI":"10.7181\/acfs.2012.13.1.4","article-title":"Bony stability and soft tissue changes after orthognathic surgery on patients with cleft","volume":"13","author":"Shin","year":"2012","journal-title":"Arch Craniofac Surg"},{"key":"R10-20241227","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1007\/s12663-020-01404-0","article-title":"Cephalometric analysis of hard and soft tissue changes following anterior maxillary osteotomy distraction in cleft maxillary hypoplasia","volume":"20","author":"Pawar","year":"2021","journal-title":"J Maxillofac Oral Surg"},{"key":"R11-20241227","doi-asserted-by":"crossref","first-page":"419","DOI":"10.5999\/aps.2015.42.4.419","article-title":"Bone and soft tissue changes after two-jaw surgery in cleft patients","volume":"42","author":"Yun","year":"2015","journal-title":"Arch Plast Surg"}],"container-title":["Journal of Pharmacy and Bioallied 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