{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:19:29Z","timestamp":1787771969217,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>This study aimed to compare the efficiencies of 0.05% clobetasol propionate, 0.1% triamcinolone acetonide, and 5% amlexanox in the management of oral lichen planus (OLP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Method:<\/jats:title>\n                    <jats:p>A total of 120 patients diagnosed with oral lichen planus were equally divided into three groups and treated with 0.05% clobetasol propionate (group A), 0.1% triamcinolone acetonide (group B), and 5% amlexanox (group C) topical medicaments. The patients were evaluated for pain using the visual analog scale (VAS) and erosive lesion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      There was a statistically significant decrease in the VAS pain scale score from day 1 to day 15 in all of the tested groups. There was also a reduction in the erosive area on the right and left buccal mucosa on the 15\n                      <jats:sup>th<\/jats:sup>\n                      day with all three tested drugs. Triamcinolone acetonide (0.1%) was effective in reducing the erosive lesions on buccal mucosa when compared with 0.05% clobetasol propionate and 5% amlexanox\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Clobetasol propionate, triamcinolone acetonide, and amlexanox were effective in treating OLP patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_984_23","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T15:06:01Z","timestamp":1709219161000},"page":"S736-S737","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of Clobetasol Propionate (0.05%), Amlexanox (5%), and Triamcinolone Acetonide (0.1%) in the Treatment of Oral Lichen Planus"],"prefix":"10.4103","volume":"16","author":[{"given":"SS Mohamed Abdulcader","family":"Riyaz","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry in Ar Rass, Qassim University, Ar Rass, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,12,20]]},"reference":[{"key":"R1-20240829","first-page":"367","article-title":"Efficacy of topical use of amlexanox and fluocinolone acetonide gels in the treatment of oral lichen planus","volume":"47","author":"Shennawy","year":"2001","journal-title":"Egypt Dent J"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S1079-2104(97)90010-X","article-title":"5% amlexanox oral paste, a new treatment for recurrent minor aphthous ulcers: II. Pharmacokinetics and demonstration of clinical safety","volume":"83","author":"Khandwala","year":"1997","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"593","DOI":"10.4103\/0970-9290.123382","article-title":"A clinical evaluation of 5% amlexanox oral paste in the treatment of minor recurrent aphthous ulcers and comparison with the placebo paste: A randomized, vehicle controlled, parallel, single center clinical trial","volume":"24","author":"Bhat","year":"2013","journal-title":"Indian J Dent Res"},{"key":"R4-20240829","first-page":"23","article-title":"Amlexanox in the treatment of recurrent minor aphthous ulcers","volume":"3","author":"Katti","year":"2011","journal-title":"Int J Dent Clin"},{"issue":"Suppl 1","key":"R5-20240829","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.4103\/0975-7406.191976","article-title":"A randomized triple-blind clinical trial to compare the effectiveness of topical triamcinolone acetonate (0.1%), clobetasol propionate (0.05%), and tacrolimus orabase (0.03%) in the management of oral lichen planus","volume":"8","author":"Sivaraman","year":"2016","journal-title":"J Pharm Bioallied Sci"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"136","DOI":"10.4103\/jiaomr.jiaomr_16_21","article-title":"Comparative evaluation of the efficacy of topical amlexanox 5%, triamcinolone acetonide 0.1%, and tacrolimus 0.03% in the treatment of oral erosive lichen planus \u2013a double-blinded randomized clinical trial","volume":"34","author":"Seth","year":"2022","journal-title":"J Indian Acad Oral Med Radiol"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.oooo.2011.10.013","article-title":"Amlexanox is as effective as dexamethasone in topical treatment of erosive oral lichen planus: A short-term pilot study","volume":"113","author":"Fu","year":"2012","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_984_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:23:17Z","timestamp":1787768597000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_984_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,20]]},"references-count":7,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_984_23","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,20]]},"assertion":[{"value":"2023-10-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}