{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:39:47Z","timestamp":1787071187548,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"\n Background:<\/jats:title>\n Periodontal and peri-implant disorders are etiologically linked to bacterial biofilms. The researchers wanted to see how well the erbium-doped yttrium aluminum garnet (Er:YAG) laser removed bacterial biofilms along with attached epithelial cells (EC), gingival fibroblasts (GF), in addition to osteoblast-like cells (OC) dentin along with titanium surfaces compared to previous therapy methods.<\/jats:p>\n <\/jats:sec>\n \n Methodology:<\/jats:title>\n 3.5 days were spent growing bacterial biofilms on standardized dentin and also titanium samplings using a sand-blasted along with the acid-etched surface. Following that, the specimens were positioned into pockets that had been formed artificially. The following approaches were used to remove biofilm: (1) Er:YAG, (2) photodynamic therapy (PDT), and (3) curette (CUR) along with supplementary PDT (CUR\/PDT). The remaining biofilms' colony forming units (CFUs) were determined, as well as the attachment of EC, GF, in addition to OC. Analysis of variance with a posthoc least significant difference was utilized in the statistical analysis.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n When compared to untreated dentin and titanium surfaces, all therapy strategies reduced total CFUs in statistically significant biofilms (\n p<\/jats:italic>\n = 0.001). On the dentin, Er:YAG was as effective as CUR and PDT, but not as effective as CUR\/PDT (\n p<\/jats:italic>\n = 0.005). The application of Er:YAG on titanium surfaces leads to statistically significantly improved biofilm eradication equated to the supplementary three therapies (all\n p<\/jats:italic>\n = 0.001). On untouched infested dentin and titanium surfaces, the counts of attached EC, GF, and OC were the lowermost. Atop the dentin, increased EC counts were detected after CUR\/PDT (\n p<\/jats:italic>\n = 0.006). On titanium, all cleaning procedures increased the counts of attached EC by a statistically significant amount (\n p<\/jats:italic>\n = 0.001), with no variations between groups. After Er:YAG decontamination, there were statistically substantially elevated amounts of GF (\n p<\/jats:italic>\n = 0.024) and OC (\n p<\/jats:italic>\n = 0.001) than on untreated surfaces.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The usage of Er:YAG laser to ablate subgingival biofilms and, specifically, to decontaminate titanium implant surfaces appears to be a promising strategy that needs further research.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_98_22","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T15:05:34Z","timestamp":1657724734000},"page":"S530-S533","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["An In Vitro study to Compare Dental Laser with other Treatment Modalities on Biofilm Ablation from Implant and Tooth Surfaces"],"prefix":"10.4103","volume":"14","author":[{"given":"Sunil Kumar","family":"Vaddamanu","sequence":"first","affiliation":[{"name":"Department of Dental Technology, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Vyas","sequence":"additional","affiliation":[{"name":"Department of Dental Technology, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumari","family":"Kavita","sequence":"additional","affiliation":[{"name":"Department of Dentistry, NMCH, Patna, Bihar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Sushma","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, School of Dental Sciences, Krishna Institute of Medical Sciences \u201cDeemed to be University (KIMSDU), Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Padmini","family":"Rani","sequence":"additional","affiliation":[{"name":"MDS Prosthodontics KIDS, KIIT University, Bhubaneswar Odisha, Phd Scholar in Prosthodontics and Crown and Bridge, KIIT University Bhubaneswar Odisha Senior Resident, SCB Dental College and Hospital, Cuttack, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arti","family":"Dixit","sequence":"additional","affiliation":[{"name":"Reader, Department of Public Health Dentistry, Vaidik Dental College & Research Centre, Daman, Daman & Diu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhumika Kamal","family":"Badiyani","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, MDS Public Health Dentistry, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,7,13]]},"reference":[{"key":"R1-20250925","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/203417a0","article-title":"Impact of the laser on dental caries","volume":"203","author":"Goldman","year":"1964","journal-title":"Nature"},{"key":"R2-20250925","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/prd.12080","article-title":"Periodontal and peri-implant wound healing following laser therapy 2015","volume":"68","author":"Aoki","year":"2000","journal-title":"Periodontol"},{"key":"R3-20250925","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1007\/s10103-011-0940-z","article-title":"In vitro inactivation of endodontic pathogens with Nd: YAG and Er:YAG lasers","volume":"27","author":"Meire","year":"2012","journal-title":"Lasers Med Sci"},{"key":"R4-20250925","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cden.2009.08.006","article-title":"Nonsurgical mechanical therapy strategies for periodontal disease","volume":"54","author":"Apatzidou","year":"2010","journal-title":"Dent Clin North Am"},{"key":"R5-20250925","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1600-051X.2008.01276.x","article-title":"Non-surgical therapy of peri-implant mucositis and peri-implantitis: A literature review","volume":"35","author":"Renvert","year":"2008","journal-title":"J Clin Periodontol"},{"key":"R6-20250925","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/jcpe.12304","article-title":"Er:YAG laser versus scaling and root planing as alternative or adjuvant for chronic periodontitis therapy: A systematic review","volume":"41","author":"Zhao","year":"2014","journal-title":"J Clin Periodontol"},{"key":"R7-20250925","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1007\/s10103-014-1692-3","article-title":"The effects of Er:YAG on the therapy of peri-implantitis: A meta-analysis of randomized controlled trials","volume":"30","author":"Yan","year":"2005","journal-title":"Lasers Med Sci"},{"key":"R8-20250925","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1034\/j.1600-0501.2002.130402.x","article-title":"Microbiological findings and host response in patients with peri-implantitis","volume":"13","author":"Hultin","year":"2002","journal-title":"Clin Oral Implants Res"},{"key":"R9-20250925","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s00784-005-0305-8","article-title":"Influence of different therapy approaches on the removal of early plaque biofilms and the viability of SAOS2 osteoblasts grown on titanium implants","volume":"9","author":"Schwarz","year":"2005","journal-title":"Clin Oral Investig"},{"key":"R10-20250925","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1600-0501.2005.01194.x","article-title":"Dynamics of initial subgingival colonization of 'pristine' peri-implant pockets","volume":"17","author":"Quirynen","year":"2006","journal-title":"Clin Oral Implants Res"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_98_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:42:47Z","timestamp":1787067767000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_98_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":10,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_98_22","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"2022-01-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}