{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:21:40Z","timestamp":1787772100009,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Zinc is vital for cellular functions, but kidney failure increases zinc deficiency risk. We compared zinc levels in hemodialysis (HD) and peritoneal dialysis (PD) patients in Isfahan, Iran.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n A retrospective study included 150 patients (75 PD and 75 HD). Serum zinc levels were assessed through photometry. Statistical analysis employed Chi-square, independent\n t<\/jats:italic>\n -test, and correlation.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Serum zinc was below normal in both groups (\n P<\/jats:italic>\n < 0.01). HD patients had lower zinc levels (70.85 \u00b1 7.68 mg\/dL) compared to PD (75.04 \u00b1 13.55 mg\/dL,\n P<\/jats:italic>\n = 0.021), remaining significant after adjusting for confounders (\n P<\/jats:italic>\n = 0.011).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Zinc levels in PD and HD patients are lower than in the general population, with HD patients having lower levels than PD patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jrms.jrms_167_23","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T12:38:12Z","timestamp":1711629492000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Serum zinc levels in hemodialysis and peritoneal dialysis patients: A retrospective observational study"],"prefix":"10.4103","volume":"29","author":[{"given":"Masoud","family":"Mahmoudi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firouzeh","family":"Moeinzadeh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdolamir","family":"Atapour","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiva","family":"Seirafian","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Isfahan Kidney Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhina","family":"Azhir","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,3]]},"reference":[{"key":"R2-20240830","doi-asserted-by":"crossref","first-page":"353","DOI":"10.2119\/2008-00033.Prasad","article-title":"Zinc in human health: Effect of zinc on immune cells","volume":"14","author":"Prasad","year":"2008","journal-title":"Mol Med"},{"key":"R3-20240830","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/ki.2013.444","article-title":"Summary of KDIGO 2012 CKD guideline: Behind the scenes, need for guidance, and a framework for moving forward","volume":"85","author":"Levin","year":"2014","journal-title":"Kidney 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deficiency in Japanese patients on peritoneal dialysis: Comparative study in patients on hemodialysis","volume":"12","author":"Shimizu","year":"2020","journal-title":"Nutrients"},{"key":"R8-20240830","first-page":"190","article-title":"Prevalence and socioeconomic predictive factors of cesarean section delivery in Ghana","volume":"35","author":"Alhassan","year":"2022","journal-title":"Menoufia Med J"},{"key":"R9-20240830","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1590\/2175-8239-jbn-2020-0040","article-title":"Cardiovascular mortality in peritoneal dialysis: The impact of mineral disorders","volume":"43","author":"Truyts","year":"2021","journal-title":"J Bras Nefrol"},{"key":"R10-20240830","doi-asserted-by":"crossref","first-page":"58","DOI":"10.5301\/ijao.5000656","article-title":"Hemodialysis versus peritoneal dialysis: An observational study in two international centers","volume":"41","author":"Lu","year":"2017","journal-title":"Int J Artif Organs"},{"key":"R11-20240830","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.3390\/jcm12041667","article-title":"Clinical significance of trace element zinc in patients with chronic kidney disease","volume":"12","author":"Fukasawa","year":"2023","journal-title":"J Clin Med"},{"key":"R12-20240830","first-page":"249","article-title":"Assessment of zinc concentration in random samples of the adult population in Shiraz, Iran","volume":"13","author":"Dabbaghmanesh","year":"2011","journal-title":"Iran Red Crescent Med J"}],"container-title":["Journal of Research in Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jrms.jrms_167_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:28:55Z","timestamp":1787768935000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jrms.jrms_167_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jrms.jrms_167_23","relation":{},"ISSN":["1735-1995","1735-7136"],"issn-type":[{"value":"1735-1995","type":"print"},{"value":"1735-7136","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"2023-03-11","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}