{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:46:37Z","timestamp":1787071597634,"version":"build-2736575974"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Several kinds of procedures have been introduced for surgical rectification of pelvic organ prolapse (POP) and\/or stress urinary incontinence (SUI) using various synthetic meshes such as polypropylene (PP) material. Polyvinylidene fluoride (PVDF) meshes have been proven to have higher biocompatibility, lower morbidity, and also less inflammatory and fibrotic reactions in comparison with PP meshes. Here, we intend to report a 2-year follow-up report of patients who had undergone transvaginal surgery using PVDF meshes to rectify POP and concomitant SUI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Between August 2015 and May 2024, 38 peri- or postmenopausal women with high-grade anterior compartment prolapse and concomitant SUI, who were nonresponsive to conservative management, were scheduled and underwent double-sling (anterior retropubic mid-urethral sling and posterior transobturator tape) surgery using a four-arm PVDF mesh. The patients were followed up for at least 24 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Thirty-eight patients were enrolled in the study and followed for an average of 5.7 years. A statistically significant subjective improvement was observed after 2 years (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.029) regarding the vaginal symptom score and SUI. Two-year outcomes for all these patients revealed an 83% anatomical success rate. Two mesh exposures were observed (5.2%) after 4 years. No other severe mesh-related complications were registered.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Double sling with PVDF implant is a safe and convenient procedure for the selected women with high-grade anterior compartment prolapse and symptomatic concomitant stress urine incontinence (SUI).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jrms.jrms_210_25","type":"journal-article","created":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T11:00:17Z","timestamp":1764586817000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Double sling with polyvinylidene fluoride implant: Evaluation of functional and anatomical outcomes of concomitant retropubic sling and anterior vaginal wall prolapse repair"],"prefix":"10.4103","volume":"30","author":[{"given":"Mahtab","family":"Zargham","sequence":"first","affiliation":[{"name":"Department of Female Urology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzaneh","family":"Sharifiaghdas","sequence":"additional","affiliation":[{"name":"Labbafinejad Center of Excellence in Urology, Urology and Nephrology Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fateme","family":"Guitynavard","sequence":"additional","affiliation":[{"name":"Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Razman Arabzadeh","family":"Bahri","sequence":"additional","affiliation":[{"name":"Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nastaran","family":"Mahmoudnejad","sequence":"additional","affiliation":[{"name":"Labbafinejad Center of Excellence in Urology, Urology and Nephrology Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faezeh Sadat","family":"Jandaghi","sequence":"additional","affiliation":[{"name":"Department of Urology, School of Medicine, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,11]]},"reference":[{"key":"R1-20251201","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00192-009-0976-9","article-title":"An International Urogynecological Association (IUGA)\/International Continence Society (ICS) joint report on the terminology for female pelvic floor 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safety of transvaginal mesh kits in the treatment of prolapse of the vaginal apex: A systematic review","volume":"116","author":"Feiner","year":"2009","journal-title":"BJOG"},{"key":"R33-20251201","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.ejogrb.2023.03.018","article-title":"Surgical results in POP\/UI surgery after using PVDF compared to other materials. A systematic review and meta-analysis","volume":"284","author":"Karalis","year":"2023","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R34-20251201","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1007\/s11255-015-1085-y","article-title":"Double-sling procedure for the surgical management of stress urinary incontinence with concomitant anterior vaginal wall prolapse","volume":"47","author":"Yonguc","year":"2015","journal-title":"Int Urol Nephrol"}],"container-title":["Journal of Research in Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jrms.jrms_210_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:49:13Z","timestamp":1787068153000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jrms.jrms_210_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":33,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jrms.jrms_210_25","relation":{},"ISSN":["1735-1995","1735-7136"],"issn-type":[{"value":"1735-1995","type":"print"},{"value":"1735-7136","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"2025-03-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}