{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T02:13:57Z","timestamp":1792030437308,"version":"4.4.0"},"reference-count":75,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>ST-elevation myocardial infarction (STEMI) remains a significant global health concern, especially in low- and middle-income regions. This study aimed to identify long-term prognostic factors among STEMI patients, offering insights into improving patient outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This study represents the 5-year follow-up of STEMI patients in the SEMI Cohort in Isfahan registry, a clinical-based registry of STEMI patients in Isfahan, Iran, from October 2015. All patients with STEMI within 24 h of symptom onset underwent a comprehensive evaluation. The dataset included demographic information, laboratory data, medical history, and clinical in-hospital data. Over 5 years, annual follow-ups were conducted to track hospitalization and patient all-cause mortality. Utilizing univariate and multivariate Cox regression proportional hazard modeling, we aimed to identify predictors of death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In this study, involving 759 patients (621 men and 138 women) with a mean age of 58.92 \u00b1 11.79 years, 158 deaths (21%) with a mean age of 70.33 \u00b1 12.66 years occurred after STEMI. In the multiple model our analysis revealed that the following variables significantly increased all-cause mortality independently: Older age (hazard ratio [HR]: 1.070,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), lower body mass index (HR: 0.890,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), hypertension status (HR: 2.441,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), lower systolic blood pressure at initial presentation (HR: 0.983,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), number of affected epicardial territories (HR: 2.979,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), lower last ejection fraction before discharge (HR: 0.951,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), lower hemoglobin level (HR: 0.747, &lt;0.001), higher plasma glucose level (HR: 1.005,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), and in-hospital complications (HR: 7.646,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study identified a range of factors that predict STEMI-related mortality. These findings are pivotal for future planning and decision-making regarding appropriate diagnostic and therapeutic strategies during patient follow-up, contributing to improved outcomes in STEMI care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jrms.jrms_314_24","type":"journal-article","created":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T22:00:10Z","timestamp":1762380010000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Long-term all-cause mortality rate after ST-elevation myocardial infarction and its predictors: ST Elevation Myocardial Infarction Cohort in Isfahan Study"],"prefix":"10.4103","volume":"30","author":[{"given":"Yasaman","family":"Shojaei","sequence":"first","affiliation":[{"name":"Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, 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