{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:31:12Z","timestamp":1787758272175,"version":"build-2784847793"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Adhesion of\n                      <jats:italic toggle=\"yes\">Candida<\/jats:italic>\n                      to host cell receptors, hemolysin production, and proteinase activity are assumed as principal virulence factors and infection establishment. These virulence factors are essential for colonization, biofilm formation, and attack on the host cells.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      A total of 97\n                      <jats:italic toggle=\"yes\">Candida albicans<\/jats:italic>\n                      isolates obtained from gastroesophageal lesions and urinary tract infections were included in the study. Adhesion assay, proteinase activity, and hemolysin production were measured. Statistical analysis was performed using the independent\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test and Chi-square test to compare quantitative and qualitative data between the two groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The adherence ability to the buccal epithelial cells was the same in the two groups. Proteinase activity was seen in all clinical isolates. Hemolytic activities were not statistically significant in the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Our results recommend that the pathogenicity of\n                      <jats:italic toggle=\"yes\">C. albicans<\/jats:italic>\n                      in the mucous membranes cannot be connected to the infected site.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jrms.jrms_35_22","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T07:22:58Z","timestamp":1659079378000},"page":"58","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of proteinase activity, hemolysin production, and adherence ability of Candida albicans isolates obtained from gastroesophageal lesions and urinary tract infections"],"prefix":"10.4103","volume":"27","author":[{"given":"Forough","family":"Rezvani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehrnoush","family":"Maheronnaghsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasoul","family":"Mohammadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-58-20240830","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2174\/1389203720666190722152415","article-title":"Virulence factors in Candida species","volume":"21","author":"Staniszewska","year":"2020","journal-title":"Curr Protein Pept Sci"},{"key":"R2-58-20240830","doi-asserted-by":"crossref","first-page":"456878","DOI":"10.1155\/2014\/456878","article-title":"Virulence factors contributing to pathogenicity of Candida tropicalis and its antifungal susceptibility 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fluconazole","volume":"50","author":"Lyon","year":"2007","journal-title":"Mycoses"},{"key":"R12-58-20240830","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1590\/S0036-46652010000300005","article-title":"Differences in exoenzyme production and adherence ability of Candida spp. isolates from catheter, blood and oral cavity","volume":"52","author":"Costa","year":"2010","journal-title":"Rev Inst Med Trop Sao Paulo"}],"container-title":["Journal of Research in Medical 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