{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T17:19:00Z","timestamp":1788974340676,"version":"build-2803163510"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Evaluation of insulin-like growth factor-1 (IGF-1) association with retinopathy of prematurity (ROP) is our object.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      This study was conducted on IGF-1 levels of 40 neonates &lt;34 weeks gestational age and 2000 g at 1\n                      <jats:sup>st<\/jats:sup>\n                      week and 4\u20136 weeks after birth. All participants were evaluated for ROP after 31 weeks of gestation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      IGF-1 levels showed a significant difference between neonates \u22641500 and 1500\u20132000 g (1 and 4\u20136 weeks,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.008,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.039, respectively). No significant association was found between IGF-1 and ROP.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Finding a meaningful association between IGF-1 and ROP requires consideration of factors affecting the IGF-1.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jrms.jrms_501_20","type":"journal-article","created":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T00:53:52Z","timestamp":1638147232000},"page":"111","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["How is insulin-like growth factor-1 correlated with retinopathy of prematurity?"],"prefix":"10.4103","volume":"26","author":[{"given":"Nahid","family":"Jafari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arezoo","family":"Karimi Moghadam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naeeme","family":"Taslimi Taleghani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neda","family":"Hosseini Nezhad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nima","family":"Motamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Jalilvand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-111-20240830","first-page":"23","article-title":"Evaluation of risk factors for retinopathy of prematurity in preterm neonates","volume":"10","author":"Khosnoud Shariati","year":"2019","journal-title":"Iran J Neonatol"},{"key":"R2-111-20240830","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1111\/apa.13350","article-title":"Insulin-like growth factor 1 has multisystem effects on foetal and preterm infant development","volume":"105","author":"Hellstr\u00f6m","year":"2016","journal-title":"Acta Paediatr"},{"key":"R3-111-20240830","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1542\/peds.112.5.1016","article-title":"Postnatal serum insulin-like growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth","volume":"112","author":"Hellstr\u00f6m","year":"2003","journal-title":"Pediatrics"},{"key":"R4-111-20240830","doi-asserted-by":"crossref","first-page":"e153","DOI":"10.1542\/neo.2-7-e153","article-title":"Retinopathy of prematurity: History, classification, and pathophysiology","volume":"2","author":"Phelps","year":"2001","journal-title":"Neoreviews"},{"key":"R6-111-20240830","first-page":"209","article-title":"Retinopathy of prematurity and serum level of insulin-like growth factor-1","volume":"51","author":"Banjac","year":"2012","journal-title":"Acta Clin Croat"},{"key":"R7-111-20240830","doi-asserted-by":"crossref","first-page":"709","DOI":"10.11622\/smedj.2013246","article-title":"Vascular endothelial growth factor and insulin-like growth factor-1 in preterm infants with retinopathy of prematurity","volume":"54","author":"Peirovifar","year":"2013","journal-title":"Singapore Med J"},{"key":"R8-111-20240830","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1097\/IAE.0000000000001247","article-title":"Postnatal serum insulin-like growth factor I and retinopathy of prematurity","volume":"37","author":"Jensen","year":"2017","journal-title":"Retina"}],"container-title":["Journal of Research in Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jrms.JRMS_501_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:16:39Z","timestamp":1787166999000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jrms.JRMS_501_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jrms.jrms_501_20","relation":{},"ISSN":["1735-1995"],"issn-type":[{"value":"1735-1995","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}