{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T15:16:06Z","timestamp":1793114166193,"version":"4.5.0"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Extended-spectrum \u00df-lactamase (ESBL)-producing\n                      <jats:italic toggle=\"yes\">Enterobacteriaceae<\/jats:italic>\n                      seem to have an extended antibiotic resistance, but have different resistance patterns throughout different sites and regions. This study aimed to evaluate the antibiotic resistance pattern of ESBL-producing\n                      <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      One hundred swab samples from patients hospitalized due to a clinical suspicion of any kind of infection (with manifestations such as fever, leukocytosis, and an active urinalysis result) were processed in Alzahra Microbiology Laboratory, Isfahan, Iran. Isolated\n                      <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                      were cultured on Mueller\u2013Hinton agar and antibiotic susceptibility was tested by Kirby\u2013Bauer disk diffusion method following the Clinical and Laboratory Standard Institute 2017 guidelines.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>ESBL-producing samples had higher antibiotic resistance rates than ESBL-non-producing samples: ceftriaxone (58.8% vs. 27.3%), cefotaxime (73.5% vs. 30.3%), ceftizoxime (76.5% vs. 33.3%), cefixime (79.4% vs. 40.9%), and cefpodoxime (73.5% vs. 53%), except for carbenicillin (29.4% vs. 48.5%). Imipenem and meropenem were the least resisted antibiotics in ESBL-producing samples (5.9% and 11.8%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      ESBL-producing\n                      <jats:italic toggle=\"yes\">Enterobacteriaceae<\/jats:italic>\n                      have a high resistance rate to third-generation cephalosporins and high susceptibility to imipenem and meropenem.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jrms.jrms_634_18","type":"journal-article","created":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T05:15:52Z","timestamp":1577078152000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and antibiotic resistance pattern of extended-spectrum beta-lactamase-producing Escherichia coli in clinical 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