{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:30:50Z","timestamp":1787758250226,"version":"build-2784847793"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Placenta adherent abnormality (PAA) is abnormal attachment of the placenta to the myometrium. This abnormal placenta binding has severe clinical consequences for the mother and the fetus. We investigated the outcomes of hypogastric arterial ligation (HAL) before hysterectomy compared to hysterectomy alone in pregnant women with PAA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>In this randomized controlled clinical trial, 70 patients were randomly allocated to HAL along with hysterectomy and hysterectomy alone groups (35 in each Group). The total amount of intraoperative blood loss, the need for intraoperative blood products transfusion, frequency of deep vein thrombosis, duration of surgery, duration of hospitalization, and visceral trauma were compared between 2 Groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Finally, 64 patients completed the study protocol with mean age of 33.84 \u00b1 4.25 years. The study groups were comparable in terms of basic baseline demographic and clinical characteristics. Visceral trauma was less frequently occurred in HAL group compared to hysterectomy alone (0% vs. 15.6%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.02). Intraoperative blood loss (1525 \u00b1 536.41 cc vs. 2075 \u00b1 889.36 cc;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001) and were significantly lower in HAL group compared to hysterectomy alone. Duration of operation (179.06 \u00b1 36.28 vs. 197.66 \u00b1 39.47;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.05) and hospitalization (4.97 \u00b1 2.20 vs. 6.10 \u00b1 2.39;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.03) also were significantly lower in HAL group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our findings suggest that prophylactic HAL has a protective effect on the reduction of blood loss and less visceral trauma in pregnant women with PAA.<\/jats:p>\n                  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