{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T06:14:03Z","timestamp":1788502443602,"version":"build-2803163510"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The objective of this study was to assess whether a district-led multifaceted e-prescribing quality-improvement intervention improved outpatient prescription completeness and selected prescribing indicators in rural Vietnamese primary care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this uncontrolled before-and-after study, 1000 health-insurance outpatient e-prescriptions were sampled before the intervention (September\u2013November 2022) and 1000 after it (March\u2013May 2023) from nine public primary healthcare facilities using the Health Information System of Vietnam Posts and Telecommunications (HIS-VNPT; locally recorded as VNPT-HIS). The intervention (December 2022\u2013February 2023) combined prescriber education, drug-information support, audit-feedback, pharmacist-prescriber cross-checking, and administrative reminders. The primary outcome was complete key dosing-instruction documentation. Secondary outcomes were other mandatory completeness fields and selected the World Health Organization\/International Network for Rational Use of Drugs prescribing indicators.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings:<\/jats:title>\n                    <jats:p>\n                      Full address documentation remained low (31\/1000 [3.1%] vs. 29\/1000 [2.9%];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.79). Complete key dosing instructions increased from 956\/1000 (95.6%) to 974\/1000 (97.4%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.03). Mean medicines per prescription did not change significantly (4.08 \u00b1 1.535 vs. 4.20 \u00b1 1.348;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.07), and all medicines were prescribed by international nonproprietary name. Antibiotic prescribing increased from 335\/1000 (33.5%) to 447\/1000 (44.7%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), vitamin prescribing from 136\/1000 (13.6%) to 190\/1000 (19.0%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001), and essential-medicine use changed only slightly (1480\/4078 [36.3%] vs. 1568\/4197 [37.4%];\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.31).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>E-prescribing may provide an infrastructure for quality improvement but requires clinical decision support and pharmacy review.<\/jats:p>\n                  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