{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:27:04Z","timestamp":1787776024506,"version":"build-2784847793"},"reference-count":56,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background &amp; objectives:<\/jats:title>\n                    <jats:p>The battle against malaria has witnessed remarkable progress in recent years, characterized by increased funding, development of life-saving tools, and a significant reduction in disease prevalence. Yet, the formidable challenge of drug resistance persists, threatening to undo these gains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      To tackle this issue, it is imperative to identify new effective drug candidates against the malaria parasite that exhibit minimal toxicity. This study focuses on discovering such candidates by targeting PfRecQ1, also known as PfBLM, a vital protein within the malaria parasite\n                      <jats:italic toggle=\"yes\">Plasmodium falciparum<\/jats:italic>\n                      . PfRecQ1 plays a crucial role in the parasite\u2019s life cycle and DNA repair processes, making it an attractive drug development target. The study employs advanced computational techniques, including molecular modeling, structure-based virtual screening (SBVS), ADMET profiling, molecular docking, and dynamic simulations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study sources ligand molecules from the extensive MCULE database and utilizes strict filters to ensure that the compounds meet essential criteria. Through these techniques, the research identifies MCULE-3763806507-0-9 as a promising antimalarial drug candidate, surpassing the binding affinity of potential antimalarial drugs. However, it is essential to underscore that drug-like properties are primarily based on\n                      <jats:italic toggle=\"yes\">in silico<\/jats:italic>\n                      experiments, and wet lab experiments are necessary to validate these candidates\u2019 therapeutic potential.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation &amp; conclusion:<\/jats:title>\n                    <jats:p>This study represents a critical step in addressing the challenge of drug resistance in the fight against malaria.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jvbd.jvbd_176_23","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T03:00:46Z","timestamp":1706583646000},"page":"389-399","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Structural exploration of the PfBLM Helicase-ATP Binding Domain and implications in the quest for antimalarial therapies"],"prefix":"10.4103","volume":"61","author":[{"given":"Hattan S","family":"Gattan","sequence":"first","affiliation":[{"name":"Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia"},{"name":"Special Infectious Agents Unit, King Fahad Medical Research center, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassam M","family":"Al-ahmadi","sequence":"additional","affiliation":[{"name":"Department of Biology, Faculty of Science, Taibah University, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah F","family":"Shater","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences. University of Tabuk, Tabuk 71491, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nizar H","family":"Saeedi","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed H","family":"Alruhaili","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology and Immunology, Faculty of Medicine, King AbdulAziz University, Jeddah, Saudi Arabia"},{"name":"Special Infectious Agents Unit, King Fahad Medical Research center, King AbdulAziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,21]]},"reference":[{"issue":"3","key":"R1-20240921","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens12030373","article-title":"Analysis of Fifty Years of Severe Malaria Worldwide Research","volume":"12","author":"Garrido-Cardenas","year":"2023","journal-title":"Pathogens"},{"issue":"03","key":"R2-20240921","doi-asserted-by":"crossref","first-page":"5","DOI":"10.24321\/0019.5138.202023","article-title":"High Burden to High Impact (HBHI) Approaches - Country Perspective for Adoption and Adaptation in India","volume":"52","author":"Kumari","year":"2020","journal-title":"Journal of Communicable Diseases"},{"issue":"1","key":"R3-20240921","doi-asserted-by":"crossref","DOI":"10.1186\/s12936-019-2806-y","article-title":"A case of Plasmodium malariae recurrence: Recrudescence or reinfection?","volume":"18","author":"Grande","year":"2019","journal-title":"Malar J"},{"key":"R4-20240921","doi-asserted-by":"crossref","DOI":"10.9734\/ijpr\/2022\/v10i330252","article-title":"Global Therapeutic Intervention on Malaria","author":"Onugha","year":"2022","journal-title":"International Journal of Pathogen Research"},{"issue":"5","key":"R5-20240921","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbapap.2016.02.016","article-title":"Plasmodium falciparum Bloom homologue, a nucleocytoplasmic protein, translocates in 3' to 5' direction and is essential for parasite growth","volume":"1864","author":"Rahman","year":"2016","journal-title":"Biochim Biophys Acta Proteins Proteom"},{"issue":"1","key":"R6-20240921","doi-asserted-by":"crossref","DOI":"10.1007\/s00709-015-0785-6","article-title":"Plasmodium falciparum Werner homologue is a nuclear protein and its biochemical activities reside in the N-terminal region","volume":"255","author":"Rahman","year":"2016","journal-title":"Protoplasma"},{"issue":"16","key":"R7-20240921","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.3390\/cells12162037","article-title":"Understanding the Human RECQ5 Helicase\u2014Connecting the Dots from DNA to Clinics","volume":"12","author":"Mo","year":"2023","journal-title":"Cells"},{"issue":"19","key":"R8-20240921","doi-asserted-by":"crossref","first-page":"12216","DOI":"10.3390\/ijerph191912216","article-title":"Global Cross-Border Malaria Control Collaborative Initiatives: A Scoping Review","volume":"19","author":"Fambirai","year":"2022","journal-title":"Int J Environ Res Public Health"},{"issue":"1","key":"R9-20240921","doi-asserted-by":"crossref","first-page":"124","DOI":"10.24321\/0019.5138.202259","article-title":"Transition of Malaria Control to Malaria Elimination in India","volume":"54","author":"Kumari","year":"2022","journal-title":"Journal of Communicable Diseases"},{"issue":"7","key":"R10-20240921","doi-asserted-by":"crossref","first-page":"e1007490","DOI":"10.1371\/journal.pgen.1007490","article-title":"RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics. Guler J, editor","volume":"14","author":"Claessens","year":"2018","journal-title":"PLoS Genet"},{"issue":"6","key":"R11-20240921","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.00956-20","article-title":"Elucidation of DNA Repair Function of PfBlm and Potentiation of Artemisinin Action by a Small-Molecule Inhibitor of RecQ Helicase. Dzikowski R, editor","volume":"5","author":"Suthram","year":"2020","journal-title":"mSphere"},{"issue":"13","key":"R12-20240921","doi-asserted-by":"crossref","first-page":"3381","DOI":"10.1093\/nar\/gkg520","article-title":"SWISS-MODEL: an automated protein homologymodeling server","volume":"51","author":"Schwede","year":"2003","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"R13-20240921","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1107\/S0021889892009944","article-title":"PROCHECK: a program to check the stereochemical quality of protein structures","volume":"26","author":"Laskowski","year":"1993","journal-title":"J Appl Crystallogr"},{"key":"R14-20240921","first-page":"1","article-title":"Identifying potential inhibitors of C-X-C motif chemokine ligand10 against vitiligo: structure-based virtual screening, molecular dynamics simulation, and principal component analysis","author":"Khan","year":"2023","journal-title":"J Biomol Struct Dyn"},{"issue":"5","key":"R15-20240921","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/cbf.3707","article-title":"Target-based virtual screening, computational multiscoring docking and molecular dynamics simulation of small molecules as promising drug candidate affecting kinesin-like protein KIFC1","volume":"40","author":"Khan","year":"2022","journal-title":"Cell Biochem Funct"},{"issue":"15","key":"R16-20240921","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1002\/elps.1150181505","article-title":"SWISS-MODEL and the Swiss-Pdb Viewer: An environment for comparative protein modeling","volume":"1S","author":"Guex","year":"1997","journal-title":"Electrophoresis"},{"issue":"2","key":"R17-20240921","article-title":"Atovaquone-proguanil for treating uncomplicated Plasmodium falciparum malaria","volume":"2021","author":"Blanshard","year":"2021","journal-title":"Cochrane Database of Systematic Review"},{"key":"R18-20240921","doi-asserted-by":"crossref","first-page":"102549","DOI":"10.1016\/j.tmaid.2023.102549","article-title":"Artemether-lumefantrine, mefloquine and atovaquone-proguanil in the treatment of uncomplicated Plasmodium falciparum malaria in travellers: A retrospective comparative study of efficacy and treatment failures","volume":"52","author":"Grebenyuk","year":"2023","journal-title":"Travel Med Infect Dis"},{"issue":"6","key":"R19-20240921","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1016\/S1473-3099(21)00692-7","article-title":"Triple therapy with artemether-lumefantrine plus amodiaquine versus artemether-lumefantrine alone for artemisininresistant, uncomplicated falciparum malaria: an open-label, randomised, multicentre trial","volume":"22","author":"Peto","year":"2022","journal-title":"Lancet Infect Dis"},{"key":"R20-20240921","article-title":"Atovaquone-proguanil for treating uncomplicated Plasmodium falciparum malaria","volume":"35","author":"Blanchard","year":"2023","journal-title":"Emergencias"},{"issue":"S1","key":"R21-20240921","doi-asserted-by":"crossref","first-page":"P17","DOI":"10.1186\/1758-2946-4-S1-P17","article-title":"http:\/\/Mcule.com: a public web service for drug discovery","volume":"4","author":"Kiss","year":"2012","journal-title":"J Cheminform"},{"issue":"7","key":"R22-20240921","doi-asserted-by":"crossref","first-page":"11820","DOI":"10.1002\/jcb.28461","article-title":"Molecular interaction of investigational ligands with human brain acetylcholinesterase","volume":"120","author":"Shakil","year":"2019","journal-title":"J Cell Biochem"},{"issue":"2","key":"R23-20240921","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s12539-017-0237-4","article-title":"Development of In Silico Protocols to Predict Structural Insights into the Metabolic Activation Pathways of Xenobiotics","volume":"10","author":"Khan","year":"2018","journal-title":"Interdiscip Sci"},{"issue":"4","key":"R24-20240921","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s12539-017-0226-7","article-title":"Structural Insight into the Mechanism of Dibenzo[a,l]pyrene and Benzo[a]pyrene-Mediated Cell Proliferation Using Molecular Docking Simulations","volume":"10","author":"Khan","year":"2018","journal-title":"Interdiscip Sci"},{"issue":"1s","key":"R25-20240921","doi-asserted-by":"crossref","first-page":"s21","DOI":"10.5530\/ijper.56.1s.39","article-title":"Identifying Natural Therapeutics against Diabetes via Inhibition of Dipeptidyl Peptidase 4: Molecular Docking and MD Simulation Study","volume":"56","author":"Kausar","year":"2022","journal-title":"Indian Journal of Pharmaceutical Education and Research"},{"issue":"5","key":"R26-20240921","doi-asserted-by":"crossref","first-page":"16","DOI":"10.14715\/cmb\/2021.67.5.3","article-title":"Identifying the alpha-glucosidase inhibitory potential of dietary phytochemicals against diabetes mellitus type 2 via molecular interactions and dynamics simulation","volume":"67","author":"Kausar","year":"2022","journal-title":"Cell Mol Biol"},{"issue":"1","key":"R27-20240921","doi-asserted-by":"crossref","first-page":"42717","DOI":"10.1038\/srep42717","article-title":"SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules","volume":"7","author":"Daina","year":"2017","journal-title":"Sci Rep"},{"issue":"6","key":"R28-20240921","doi-asserted-by":"crossref","first-page":"923","DOI":"10.3390\/ijerph16060923","article-title":"A Molecular Docking Approach to Evaluate the Pharmacological Properties of Natural and Synthetic Treatment Candidates for Use against Hypertension","volume":"16","author":"Attique","year":"2019","journal-title":"Int J Environ Res Public Health"},{"issue":"21","key":"R29-20240921","doi-asserted-by":"crossref","first-page":"3867","DOI":"10.1021\/jm000292e","article-title":"Prediction of Drug Absorption Using Multivariate Statistics","volume":"45","author":"Egan","year":"2000","journal-title":"J Med Chem"},{"issue":"3","key":"R30-20240921","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0169-409X(02)00004-2","article-title":"Prediction of intestinal permeability","volume":"54","author":"Egan","year":"2002","journal-title":"Adv Drug Deliv Rev"},{"issue":"7","key":"R31-20240921","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1021\/jm901137j","article-title":"New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays","volume":"53","author":"Baell","year":"2010","journal-title":"J Med Chem"},{"issue":"3","key":"R32-20240921","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/cmdc.200700139","article-title":"Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases","volume":"3","author":"Brenk","year":"2008","journal-title":"Chem Med Chem"},{"issue":"16","key":"R33-20240921","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1002\/jcc.20291","article-title":"GROMACS: Fast, flexible, and free","volume":"26","author":"Van Der Spoel","year":"2005","journal-title":"J Comput Chem"},{"issue":"12","key":"R34-20240921","doi-asserted-by":"crossref","first-page":"3144","DOI":"10.1021\/ci300363c","article-title":"Automation of the CHARMM General Force Field (CGenFF) I: Bond Perception and Atom Typing","volume":"52","author":"Vanommeslaeghe","year":"2012","journal-title":"J Chem Inf Model"},{"issue":"4","key":"R35-20240921","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1002\/jcc.21367","article-title":"CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields","volume":"31","author":"Vanommeslaeghe","year":"2010","journal-title":"J Comput Chem"},{"issue":"9","key":"R36-20240921","doi-asserted-by":"crossref","first-page":"3668","DOI":"10.1063\/1.470043","article-title":"Accuracy and efficiency of the particle mesh Ewald method","volume":"103","author":"Petersen","year":"1995","journal-title":"J Chem Phys"},{"issue":"19","key":"R37-20240921","doi-asserted-by":"crossref","first-page":"3943","DOI":"10.1021\/acs.jpca.0c01684","article-title":"An Exact Ewald Summation Method in Theory and Practice","volume":"124","author":"Stenberg","year":"2020","journal-title":"J Phys Chem A"},{"issue":"7","key":"R38-20240921","doi-asserted-by":"crossref","first-page":"2938","DOI":"10.1021\/acs.jctc.5b00190","article-title":"Properties of Organic Liquids when Simulated with LongRange Lennard-Jones Interactions","volume":"11","author":"Fischer","year":"2015","journal-title":"J Chem Theory Comput"},{"issue":"9","key":"R39-20240921","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.3390\/biom12091184","article-title":"Local Backbone Geometry Plays a Critical Role in Determining Conformational Preferences of Amino Acid Residues in Proteins","volume":"12","author":"Balasco","year":"2022","journal-title":"Biomolecules"},{"issue":"2","key":"R40-20240921","doi-asserted-by":"crossref","first-page":"e25","DOI":"10.5808\/gi.23001","article-title":"Computational approaches for molecular characterization and structure-based functional elucidation of a hypothetical protein from Mycobacterium tuberculosis","volume":"21","author":"Saikat","year":"2023","journal-title":"Genomics Inform"},{"issue":"1","key":"R41-20240921","doi-asserted-by":"crossref","first-page":"107939","DOI":"10.1016\/j.jsb.2023.107939","article-title":"Revisiting the Ramachandran plot based on statistical analysis of static and dynamic characteristics of protein structures","volume":"215","author":"Park","year":"2023","journal-title":"J Struct Biol"},{"issue":"16_suppl","key":"R42-20240921","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1200\/JCO.2022.40.16_suppl.2062","article-title":"Predicting CNS penetration of precision medicine therapies in oncology: A comparison of the CNS TAP tool and the BOILED-Egg computational model","volume":"40","author":"Walker","year":"2022","journal-title":"Journal of Clinical Oncology"},{"issue":"33","key":"R43-20240921","doi-asserted-by":"crossref","first-page":"51","DOI":"10.4103\/0973-1296.108140","article-title":"Dietary phytochemicals as potent chemotherapeutic agents against breast cancer: Inhibition of NF-\u03baB pathway via molecular interactions in rel homology domain of its precursor protein p105","volume":"9","author":"Khan","year":"2013","journal-title":"Pharmacogn Mag"},{"issue":"1","key":"R44-20240921","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1080\/14756366.2019.1692828","article-title":"Identifying novel sphingosine kinase 1 inhibitors as therapeutics against breast cancer","volume":"35","author":"Khan","year":"2020","journal-title":"J Enzyme Inhib Med Chem"},{"issue":"5","key":"R45-20240921","doi-asserted-by":"crossref","first-page":"12993","DOI":"10.33263\/BRIAC115.1299313004","article-title":"Combinatorial Design to Decipher Novel Lead Molecule against Mycobacterium tuberculosis","volume":"11","author":"Ajijur","year":"2021","journal-title":"Biointerface Res Appl Chem"},{"issue":"1","key":"R46-20240921","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1021\/cc9800071","article-title":"A KnowledgeBased Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases","volume":"1","author":"Ghose","year":"1999","journal-title":"J Comb Chem"},{"issue":"12","key":"R47-20240921","doi-asserted-by":"crossref","first-page":"261523","DOI":"10.1021\/jm020017n","article-title":"Molecular Properties That Influence the Oral Bioavailability of Drug Candidates","volume":"45","author":"Veber","year":"2002","journal-title":"J Med Chem"},{"issue":"12","key":"R48-20240921","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1021\/jm015507e","article-title":"Simple Selection Criteria for Drug-like Chemical Matter","volume":"44","author":"Muegge","year":"2001","journal-title":"J Med Chem"},{"issue":"9","key":"R49-20240921","first-page":"3164","article-title":"A Bioavailability Score","volume":"48","author":"Martin","year":"2005","journal-title":"JMed Chem"},{"issue":"1","key":"R50-20240921","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.33263\/BRIAC121.10961109","article-title":"Identification of Potential Lead Molecules against Dibenzo [a,l]pyrene-induced Mammary Cancer through Targeting Cytochrome P450 1A1, 1A2, and 1B1 Isozymes","volume":"12","author":"MU","year":"2021","journal-title":"Biointerface Res Appl Chem"},{"issue":"20","key":"R51-20240921","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1111\/jcmm.17940","article-title":"Antimalarial drug discovery against malaria parasites through haplopine modification: An advanced computational approach","volume":"27","author":"Akash","year":"2023","journal-title":"J Cell Mol Med"},{"issue":"3","key":"R52-20240921","doi-asserted-by":"crossref","first-page":"291","DOI":"10.2174\/1570180815666180604085626","article-title":"Assessing the Antimalarial Potentials of Phytochemicals: Virtual Screening, Molecular Dynamics and In-Vitro Investigations","volume":"16","author":"Patel","year":"2019","journal-title":"Lett Drug Des Discov"},{"issue":"11","key":"R53-20240921","doi-asserted-by":"crossref","first-page":"3803","DOI":"10.3390\/ijms21113803","article-title":"Identification of Selective Novel Hits against Plasmodium falciparum Prolyl tRNA Synthetase Active Site and a Predicted Allosteric Site Using In Silico Approaches","volume":"21","author":"Nyamai","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"8","key":"R54-20240921","doi-asserted-by":"crossref","first-page":"e0289887","DOI":"10.1371\/journal.pone.0289887","article-title":"Exploring the potential of approved drugs for triple-negative breast cancer treatment by targeting casein kinase 2: Insights from computational studies. Eldehna WM, editor","volume":"18","author":"Shoaib","year":"2023","journal-title":"PLoS One"},{"issue":"1","key":"R55-20240921","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s13065-023-00980-9","article-title":"Repurposing Amphotericin B: anti-microbial, molecular docking and molecular dynamics simulation studies suggest inhibition potential of Amphotericin B against MRSA","volume":"17","author":"Farid","year":"2023","journal-title":"BMC Chem"},{"issue":"2","key":"R56-20240921","doi-asserted-by":"crossref","first-page":"323","DOI":"10.3897\/pharmacia.70.e101989","article-title":"Molecular docking and dynamics analysis of halogenated imidazole chalcone as anticancer compounds","volume":"70","author":"Haryadi","year":"2023","journal-title":"Pharmacia"}],"container-title":["Journal of Vector Borne Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/JVBD.JVBD_176_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:47:09Z","timestamp":1787773629000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/JVBD.JVBD_176_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":56,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jvbd.jvbd_176_23","relation":{},"ISSN":["0972-9062"],"issn-type":[{"value":"0972-9062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2023-11-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}