{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:23:22Z","timestamp":1787765002347,"version":"build-2784847793"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background &amp; objectives:<\/jats:title>\n                    <jats:p>Bandung City, West Java, Indonesia, is a hyperendemic area for dengue virus (DENV) infections. However, data on virus distribution in this area is currently limited. This study aims to assess the distribution of serotypes and genotypes of DENV isolated from dengue patients in primary healthcare facilities (PHC) in 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study was conducted in three PHCs in Bandung City from May to October 2018. Suspected dengue patients with a fever lasting more than five days were enrolled. Demographic and clinical data were collected upon enrollment. Dengue NS1 rapid diagnostic test (RDT) was followed by RT-PCR and nested PCR performed on patients\u2019 serum samples. A phylogenetic tree was constructed based on E-gene sequence data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 236 suspected dengue patients were enrolled in this study, with 51 confirmed dengue infections based on the NS1 rapid test. Among these 51 cases, 23 (45%) were positive by RT-PCR (2 DENV-1, 6 DENV-2, 10 DENV-3, 3 DENV-4, and 2 with mixed DENV serotypes). The predominance DENV-3 in 2018 was consistent with the reports from 2008, indicating the same predominant serotype circulated in the area. Phylogenetic analysis revealed that DENV-1 genotype 1 and DENV-3 genotype 1 were circulating in Bandung.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation &amp; conclusion:<\/jats:title>\n                    <jats:p>All four DENV serotypes were identified in samples collected from PHC Neglasari, Padasuka, and Sukajadi, confirming that Bandung is a hyperendemic area. Strengthening vector control measures is crucial to prevent further transmission of dengue infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jvbd.jvbd_23_24","type":"journal-article","created":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:00:50Z","timestamp":1753891250000},"page":"190-197","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Molecular virology profiles of dengue cases in Bandung, Indonesia"],"prefix":"10.4103","volume":"63","author":[{"given":"Nisa","family":"Fauziah","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia"},{"name":"Research Center for Care and Control of Infectious Disease, Universitas Padjadjaran, Bandung, West Java, Indonesia"},{"name":"Doctoral Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia"},{"name":"Universitas 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