{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:20:16Z","timestamp":1787847616206,"version":"build-2784847793"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n                    <jats:title>Background and objectives:<\/jats:title>\n                    <jats:p>\n                      Synanthropic rodents cohabiting with the human and livestock are potential reservoirs for several zoonotic pathogens, which include\n                      <jats:italic toggle=\"yes\">Leptospira<\/jats:italic>\n                      spp,\n                      <jats:italic toggle=\"yes\">Yersinia<\/jats:italic>\n                      spp,\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">Toxoplasma<\/jats:italic>\n                      spp. In view of the higher incidence of leptospirosis in human and animals, this study was carried out to analyse the role of rodents and shrews in the transmission of pathogenic\n                      <jats:italic toggle=\"yes\">Leptospira<\/jats:italic>\n                      spp in Puducherry, India.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      The rodents\/shrews were trapped at 15 randomly selected sites in Puducherry, using Sherman traps between July to December 2022. The DNA from the blood and kidney of the rodents was extracted individually. The presence of pathogenic\n                      <jats:italic toggle=\"yes\">Leptospira<\/jats:italic>\n                      spp in the rodent DNA sample was screened by Real-time PCR, targeting the\n                      <jats:italic toggle=\"yes\">lipl32<\/jats:italic>\n                      gene. Further\n                      <jats:italic toggle=\"yes\">secY<\/jats:italic>\n                      gene was amplified and analysed to identify the pathogenic\n                      <jats:italic toggle=\"yes\">Leptospira<\/jats:italic>\n                      spp.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Five kidney DNA samples (\n                      <jats:italic toggle=\"yes\">Rattus rattus<\/jats:italic>\n                      = 1 and\n                      <jats:italic toggle=\"yes\">Suncus murinus<\/jats:italic>\n                      = 4) were tested positive for\n                      <jats:italic toggle=\"yes\">Leptospira<\/jats:italic>\n                      sp by Real time PCR. The BLAST, phylogeny and sequence alignment studies of\n                      <jats:italic toggle=\"yes\">secY<\/jats:italic>\n                      gene indicated the circulation\n                      <jats:italic toggle=\"yes\">Leptospira borgpetersenii<\/jats:italic>\n                      in the synanthropic rodents.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretations &amp; conclusion:<\/jats:title>\n                    <jats:p>\n                      We first report, that the\n                      <jats:italic toggle=\"yes\">Suncus murinus<\/jats:italic>\n                      , the Asian house shrew, has also been found harbouring the pathogenic\n                      <jats:italic toggle=\"yes\">Leptospira<\/jats:italic>\n                      sp. The shrews and the black rat harbouring the pathogenic\n                      <jats:italic toggle=\"yes\">Leptospira<\/jats:italic>\n                      sp in our study indicates that they are one among the key environmental determinants for Leptospirosis transmission to human and animals in Puducherry.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jvbd.jvbd_332_25","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T08:00:08Z","timestamp":1780041608000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Report on the detection of pathogenic Leptospira sp. in synanthropic rodents and Asian house shrews (Suncus Murinus) from Puducherry, India, 2022"],"prefix":"10.4103","author":[{"given":"Panneer","family":"Devaraju","sequence":"first","affiliation":[{"name":"Unit of One Health, ICMR-Vector Control Research Centre (ICMR-VCRC), Indira Nagar, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nivedha","family":"Devanathan","sequence":"additional","affiliation":[{"name":"Department of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research (RIVER), Kurumbapet, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirak K","family":"Mukhopadhyay","sequence":"additional","affiliation":[{"name":"Department of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research (RIVER), Kurumbapet, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishan K","family":"Sihag","sequence":"additional","affiliation":[{"name":"Unit of One Health, ICMR-Vector Control Research Centre (ICMR-VCRC), Indira Nagar, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Tiwari","sequence":"additional","affiliation":[{"name":"Unit of One Health, ICMR-Vector Control Research Centre (ICMR-VCRC), Indira Nagar, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmy","family":"Srinivasn","sequence":"additional","affiliation":[{"name":"Unit of One Health, ICMR-Vector Control Research Centre (ICMR-VCRC), Indira Nagar, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouttou V","family":"Srinivas","sequence":"additional","affiliation":[{"name":"Department of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research (RIVER), Kurumbapet, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayalakshmi","family":"Vasu","sequence":"additional","affiliation":[{"name":"Department of Veterinary Microbiology, Rajiv Gandhi Institute of Veterinary Education and Research (RIVER), Kurumbapet, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,5,27]]},"container-title":["Journal of Vector Borne Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jvbd.jvbd_332_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:24:15Z","timestamp":1787844255000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jvbd.jvbd_332_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,27]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4103\/jvbd.jvbd_332_25","relation":{},"ISSN":["0972-9062"],"issn-type":[{"value":"0972-9062","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,27]]},"assertion":[{"value":"2025-11-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}