{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T20:58:44Z","timestamp":1788469124811,"version":"build-2803163510"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>A survey of neonates with esophageal atresia and tracheoesophageal fistula (EA \u00b1 TEF) to determine additional factors responsible for poor surgical outcomes in our institution where employing an improved standard of care can ameliorate the outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>We carried out a retrospective review of 54 neonates, who underwent surgical repair of EA\u00b1 TEF over a 5-year period. We collected data regarding the patients\u2019 demographics, perioperative findings, records of neonatal intensive care, and ascertained the effects of gender, gestational age, birth weight, age at operation, type of anomaly, coexisting major anomalies, preoperative inotrope therapy, and duration of postoperative ventilation on the surgical outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mortality rate was 51.9%, out of which, 42.8% of neonates succumbed to ventilator-associated conditions. Age at the time of surgery, gestational age, preoperative inotrope support, presence of coexisting anomalies, and duration of postoperative ventilation were determined as the significant variables predicting mortality(\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). The area under the Receiver Operating Curve showed the duration of postoperative ventilation as the best indicator of mortality. The Logistic regression model (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      = 11.204,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.019) with the above-mentioned variables showed that neonates who were operated before 2.5 days and who required &lt;74.5 hours of postoperative ventilation were 3.91 and 48.30 times more likely to survive respectively, than their counterparts.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A delay in surgery due to delayed diagnosis and or delayed transportation to tertiary centres and prolonged ventilatory support have an additional detrimental effect on the surgical outcomes of EA \u00b1 TEF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jwas.jwas_100_22","type":"journal-article","created":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T06:37:17Z","timestamp":1694759837000},"page":"30-36","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Esophageal Atresia and Tracheoesophageal Fistula"],"prefix":"10.4103","volume":"12","author":[{"given":"Partha","family":"Chakraborty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sourav","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kartik Chandra","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj Kumar","family":"Halder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunadhar","family":"Jana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kallol","family":"Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20240907","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s13312-017-1073-7","article-title":"Congenital malformations to birth defects - the Indian scenario","volume":"54","author":"Mathur","year":"2017","journal-title":"Indian Pediatr"},{"key":"R2-6-20240907","first-page":"1626","article-title":"Associated Congenital Anomalies with Esophageal Atresia and their Impact on Survival in an Indian Scenario","volume":"3","author":"Sharma","year":"2016","journal-title":"Int J Contemp Med Res"},{"key":"R3-6-20240907","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/s00383-020-04639-7","article-title":"Tracheoesophageal fistula in the developing world: Are we ready for thoracoscopic repair?","volume":"36","author":"Alslaim","year":"2020","journal-title":"Pediatr Surg Int"},{"key":"R4-6-20240907","doi-asserted-by":"crossref","first-page":"234","DOI":"10.4103\/1117-1936.164838","article-title":"H-type tracheo-oesophageal fistula: A diagnostic challenge in a resource-poor country. 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