{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:40:07Z","timestamp":1787071207231,"version":"build-2736575974"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T00:00:00Z","timestamp":1738627200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["J West Afr Coll Surg"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Soft tissue sarcomas constitute less than 1% of all neoplasms, with a third of malignant tumours in the retroperitoneum being sarcomas and liposarcoma being the commonest. Local aggressiveness and clinical non-specificity make treatment challenging. A 52-year-old man presented with a massive lump in the abdomen. Surgery following work-up indicated a well-differentiated retroperitoneal liposarcoma (RPLS) with intraperitoneal and scrotal extension and weighed a substantial 6.8 kg. Treatment required meticulous local resection preserving the functionality. RPLS manifests as a large, locally advanced lesion with intraperitoneal extension, but extension into the inguinal canal is unknown. Being low grade, distant metastasis is infrequent, and the challenge lies in achieving effective local control and preventing local recurrence. The preferred treatment involves radical resection incorporating\n                    <jats:italic toggle=\"yes\">en bloc<\/jats:italic>\n                    resection of involved structures. Strategic neoadjuvant and adjuvant therapies, tailored to specific tumour histology, may enhance local control and overall survival. Radical resection of the tumour from the mesentery of the large and small bowel, preserving their vascularity along with retroperitoneal component, albeit in parts, was achieved and is the first-line cure in RPLS. In select cases, individualised chemotherapy and radiation therapy may offer a survival benefit.\n                  <\/jats:p>","DOI":"10.4103\/jwas.jwas_119_24","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T11:10:14Z","timestamp":1738667414000},"page":"87-91","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Another Addition to Abdomen\u2019s Pandora\u2019s Box: Multi-compartment Enormous Liposarcoma"],"prefix":"10.4103","volume":"16","author":[{"given":"Vikram Singh","family":"Chauhan","sequence":"first","affiliation":[{"name":"Department of Surgery, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Purshotam Dass","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja","family":"Parashar","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,4]]},"reference":[{"key":"CIT0001-20260206","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ijscr.2015.02.019","article-title":"Giant retroperitoneal liposarcoma: Case report and review of the literature","volume":"9","author":"Caizzone","year":"2015","journal-title":"Int J Surg Case Rep"},{"key":"CIT0002-20260206","doi-asserted-by":"crossref","first-page":"39","DOI":"10.21037\/cco.2018.07.05","article-title":"Surgical management of retroperitoneal sarcoma and opportunities for global collaboration","volume":"7","author":"Wang","year":"2018","journal-title":"Chin Clin Oncol"},{"key":"CIT0003-20260206","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fsurg.2015.00004","article-title":"Retroperitoneal liposarcoma: Current insights in diagnosis and treatment","volume":"2","author":"Matthyssens","year":"2015","journal-title":"Front Surg"},{"issue":"Suppl_7","key":"CIT0004-20260206","first-page":"vii92","article-title":"Soft tissue and visceral sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up","volume":"23","year":"2012","journal-title":"Ann Oncol"},{"key":"CIT0005-20260206","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/bjs.5967","article-title":"Retroperitoneal sarcoma","volume":"94","author":"Thomas","year":"2007","journal-title":"Br J Surg"},{"key":"CIT0006-20260206","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.ejso.2008.11.003","article-title":"Primary and locally recurrent retroperitoneal soft-tissue sarcoma: Local control and survival","volume":"35","author":"Lehnert","year":"2009","journal-title":"Eur J Surg Oncol"},{"key":"CIT0007-20260206","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.jamcollsurg.2017.01.044","article-title":"Incidence and adverse prognostic implications of histopathologic organ invasion in primary retroperitoneal sarcoma","volume":"224","author":"Fairweather","year":"2017","journal-title":"J Am Coll Surg"},{"key":"CIT0008-20260206","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1067\/j.cpsurg.2009.01.004","article-title":"Retroperitoneal and intra-abdominal sarcoma","volume":"46","author":"Liles","year":"2009","journal-title":"Curr Probl Surg"},{"key":"CIT0009-20260206","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/00000658-199809000-00008","article-title":"Retroperitoneal soft-tissue sarcoma: Analysis of 500 patients treated and followed at a single institution","volume":"228","author":"Lewis","year":"1998","journal-title":"Ann Surg"},{"key":"CIT0010-20260206","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/bjs.5967","article-title":"Retroperitoneal sarcoma","volume":"94","author":"Thomas","year":"2007","journal-title":"Br J Surg"},{"key":"CIT0011-20260206","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1200\/JCO.2008.18.0802","article-title":"Primary retroperitoneal sarcomas: A multivariate analysis of surgical factors associated with local control","volume":"27","author":"Bonvalot","year":"2009","journal-title":"J Clin Oncol"},{"key":"CIT0012-20260206","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1093\/annonc\/mdr323","article-title":"Frontline extended surgery is associated with improved survival in retroperitoneal low- to intermediate-grade soft tissue sarcomas","volume":"23","author":"Gronchi","year":"2012","journal-title":"Ann Oncol"},{"key":"CIT0013-20260206","doi-asserted-by":"crossref","first-page":"1971","DOI":"10.1002\/cncr.30572","article-title":"Postrelapse outcomes after primary extended resection of retroperitoneal sarcoma: A report from the Trans-Atlantic RPS Working Group","volume":"123","author":"MacNeill","year":"2017","journal-title":"Cancer"},{"key":"CIT0014-20260206","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1245\/s10434-016-5523-6","article-title":"Results of resection for recurrent or residual retroperitoneal sarcoma after failed primary treatment","volume":"24","author":"Hamilton","year":"2017","journal-title":"Ann Surg Oncol"},{"key":"CIT0015-20260206","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.jamcollsurg.2009.12.024","article-title":"Recurrent retroperitoneal sarcoma: Impact of biology and therapy on outcomes","volume":"210","author":"Grobmyer","year":"2010","journal-title":"J Am Coll Surg"}],"container-title":["Journal of West African College of Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jwas.jwas_119_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:43:05Z","timestamp":1787067785000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jwas.jwas_119_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,4]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jwas.jwas_119_24","relation":{},"ISSN":["2276-6944","2992-5827"],"issn-type":[{"value":"2276-6944","type":"print"},{"value":"2992-5827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,4]]},"assertion":[{"value":"2024-09-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}