{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:36:59Z","timestamp":1787071019888,"version":"build-2736575974"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T00:00:00Z","timestamp":1757116800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["J West Afr Coll Surg"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The role of chlamydia infection in the causation of male infertility has not been conclusively evaluated, especially in the developing countries of sub-Saharan Africa that are worst affected by infertility. Understanding the relationship between the two will guide the deployment of preventive efforts and investigative approaches more scientifically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients, Materials, and Methods:<\/jats:title>\n                    <jats:p>This was a case\u2013control study of two groups of males: 68 male partners of infertile couples with abnormal semen parameters attending a fertility clinic and 68 age-matched male partners (with normal semen parameters) of females attending the family planning clinic as controls at two tertiary hospitals in Delta State. The prevalence of chlamydial sero-positivity, the socio-demographic characteristics, sexual and reproductive characteristics, and chlamydial serology of all the participants were determined and compared using appropriate statistical tools.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Most (41.2%) of the participants were in the 35\u201339 years age category; they were all married and were mostly (66.2%) skilled workers. The overall prevalence of chlamydia sero-positivity in this study was 11.8%. The prevalence of chlamydia sero-positivity was signi\ufb01cantly higher amongst the study group (19.1%) compared with controls (4.4%) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 001). Chlamydial sero-positivity was significantly associated with oligospermia and teratozoospermia. On bivariate analysis, being in the infertile group (crude OR: 5.12,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.008), history of a genital ulcer (crude OR: 0.124,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.042), and history of dysuria (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.008) were significantly associated with chlamydial trachomatis sero-positivity. On multivariate logistic regression analysis, none of these covariates were found to be independent predictors of chlamydia trachomatis sero-positivity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>There was a significant association between chlamydia trachomatis infection and abnormal semen parameters. There were no identified independent predictors of chlamydia trachomatis sero-positivity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jwas.jwas_178_24","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T10:01:53Z","timestamp":1757412113000},"page":"193-198","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Association of Chlamydia Trachomatis Sero-Positivity with Male Infertility in the Niger-Delta Region of Nigeria: A Case\u2013Control Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Newton","family":"Asaboro","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Delta State University Teaching Hospital, Oghara, Delta, Nigeria"},{"name":"Department of Obstetrics and Gynecology, Faculty of Clinical Medicine, College of Health Sciences, Delta State University, Abraka, Delta, 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