{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:40:04Z","timestamp":1787071204897,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T00:00:00Z","timestamp":1738627200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["J West Afr Coll Surg"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm occurring outside the bone marrow, predominantly in the head and neck region. Representing 3%\u20135% of all plasma cell neoplasms, EMP poses significant diagnostic and therapeutic challenges due to its rarity and,proximity to vital structures. We report two cases of EMP involving the nasal cavity, paranasal sinuses, and nasopharynx. A 30-year-old male presented with right diplopia, headache, and bilateral nasal blockage. Examination revealed a nasopharyngeal mass with bony erosion and multiple osteolytic lesions. Histopathology and immunohistochemistry confirmed plasmacytoma, and systemic involvement was excluded. The patient underwent chemoradiotherapy with satisfactory outcomes. A 27-year-old female presented with nasal bleeding, progressive nasal blockage, facial swelling, snoring, and anosmia. Imaging revealed a mass originating from the left maxillary sinus extending to adjacent structures. Histopathology and immunohistochemistry confirmed plasmacytoma. Systemic workup was negative. The patient was treated with radiotherapy, with a good treatment outcomes. EMP of the nasal cavity, paranasal sinuses, and nasopharynx is rare, particularly in younger patients.<\/jats:p>\n                  <jats:p>Accurate diagnosis and appropriate treatment, often involving radiotherapy, are crucial for favorable outcomes. Awareness and a high index of suspicion are essential for early diagnosis and management.<\/jats:p>","DOI":"10.4103\/jwas.jwas_93_24","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T11:09:03Z","timestamp":1738667343000},"page":"497-500","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Extramedullary Plasmacytoma of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx: Report of Two Cases and Review of Literature"],"prefix":"10.4103","volume":"15","author":[{"given":"Saadat Titilayo","family":"Yahaya","sequence":"first","affiliation":[{"name":"ENT Department, Lagos State University Teaching Hospital, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurudeen Adebola","family":"Shofoluwe","sequence":"additional","affiliation":[{"name":"Division of Ear-Nose and Throat, Department of Surgery, Faculty of Clinical Science, College of Medical Sciences Ahmadu Bello University and Ahmadu Bello University Teaching Hospital, Zaria, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idris","family":"Abdullahi","sequence":"additional","affiliation":[{"name":"Division of Ear-Nose and Throat, Department of Surgery, Faculty of Clinical Science, College of Medical Sciences Ahmadu Bello University and Ahmadu Bello University Teaching Hospital, Zaria, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdurahman","family":"Omodele","sequence":"additional","affiliation":[{"name":"Division of Ear-Nose and Throat, Department of Surgery, Faculty of Clinical Science, College of Medical Sciences Ahmadu Bello University and Ahmadu Bello University Teaching Hospital, Zaria, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamila","family":"Lawal","sequence":"additional","affiliation":[{"name":"Department of Surgery, Barau Dikko Teaching Hospital and Kaduna State University, Kaduna State, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amina Mohammad","family":"Abdullahi","sequence":"additional","affiliation":[{"name":"Department of ENT, Federal Medical Centre, Abuja, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasheedat","family":"Sanni","sequence":"additional","affiliation":[{"name":"Department of Clinical Services, National Ear Care Centre, Kaduna, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manir Hamza","family":"Anka","sequence":"additional","affiliation":[{"name":"Department of ENT, Aminu Kano Teaching Hospital, Kano, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,4]]},"reference":[{"key":"CIT0001-20250905","doi-asserted-by":"crossref","first-page":"363","DOI":"10.5812\/ircmj.2209","article-title":"Extramedullary plasmacytoma of the nasal cavity report of three cases with review of the 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