{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:30:56Z","timestamp":1787758256599,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Endoscopic management of colorectal polyps includes detection, characterization, and therapeutic strategies. Pit pattern analysis is a useful tool when differentiating neoplastic and non-neoplastic colorectal polyps.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To correlate pit pattern characterization of colorectal polyps using SPIES endoscopy and the histopathology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      Total colonoscopy was performed on 189 patients by same endoscopist from January 2020 to September 2021 using Image 1 Connect (TC200), Image 1 H3-Link (TC300) and video-colonoscope (Karl Storz, Tuttlingen, Germany). Identified polyps were classified using Paris classification for mucosal lesions and the pit pattern according to Kudo's modified criteria using SPIES endoscopy. All lesions were diagnosed by histopathological examination. Kappa index (\n                      <jats:italic toggle=\"yes\">\u03ba<\/jats:italic>\n                      ) was used to evaluate the agreement of SPIES endoscopy Kudo's pit classification with the histopathological diagnosis. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were independently determined.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result:<\/jats:title>\n                    <jats:p>\n                      Thirty-four polyps were detected in twenty-nine patients with twenty-one (61.8%, 21\/34) polyps histologically confirmed as neoplastic. SPIES endoscopy characterized seventeen (50%, 17\/34) of the polyps as neoplastic, four (1.8%, 4\/34) as non-neoplastic (false negative) and four (1.8%, 4\/34) as false positives. The sensitivity and specificity of SPIES endoscopy were 81.0% and 69.2% respectively and same values for PPV and NPV. The diagnosis of neoplastic polyps by SPIES endoscopy was in moderate agreement with histopathological diagnosis (\n                      <jats:italic toggle=\"yes\">\u03ba<\/jats:italic>\n                      \u2009=\u20090.502)\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>SPIES endoscopy is a useful, rapid, and non-invasive tool in the endoscopic assessment of colorectal polyps.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jwas.jwas_96_22","type":"journal-article","created":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T07:34:04Z","timestamp":1661585644000},"page":"17-22","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Pit Pattern Analysis of Colorectal Polyps Using Storz Professional Image Enhancement System (Spies) 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