{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:22:03Z","timestamp":1787772123433,"version":"build-2784847793"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"120","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    Functional dysphonia can impair the language expression ability and adversely affect the career development of some patients. Therefore, an active exploration of effective treatment options is imperative. This study investigated the effect of Akson therapy on acoustic parameters in patients with functional dysphonia.\n                    <jats:bold>Materials and Methods:<\/jats:bold>\n                    In this retrospective analysis, 79 patients with functional dysphonia who received conventional voice correction training from June 2020 to June 2021 were included in the reference group (RG). Our hospital has implemented Akson therapy since July 2021. Correspondingly, 72 patients with functional dysphonia who underwent Akson therapy from July 2021 to July 2022 were enrolled in the observation group (OG). The acoustic parameters such as fundamental frequency (F0), jitter, shimmer, and normalized noise energy (NNE); the aerodynamic parameters including maximum phonation time (MPT), mean airflow rate (MFR), and Voice Handicap Index-10 (VHI-10) score; and the Grade, Roughness, Breathiness, Asthenia, and Strain scale (GRBAS) score were measured before and after treatment and compared between the two groups.\n                    <jats:bold>Results:<\/jats:bold>\n                    The F0, jitter, shimmer, NNE, MPT, and MFR values as well as the VHI-10 score and the grade (G), roughness (R), and breathiness (B) scores on the GRBAS did not significantly differ between the two groups before treatment (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &gt; 0.05). However, significantly lower F0, jitter, shimmer, NNE, and MFR values and higher MPT levels were found in the OG compared to the RG after treatment (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.001). Furthermore, the VHI-10 score and the G, R, and B scores were significantly lower in the OG than in the RG after treatment (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; 0.001), whereas the asthenia (A) and strain (S) scores remained at 0 before and after treatment.\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Akson therapy can improve the acoustic parameters of patients with functional dysphonia to a certain extent, indicating its potential application value.\n                  <\/jats:p>","DOI":"10.4103\/nah.nah_99_23","type":"journal-article","created":{"date-parts":[[2024,4,3]],"date-time":"2024-04-03T23:00:34Z","timestamp":1712185234000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Akson Therapy on Acoustic Parameters in Patients with Functional Dysphonia"],"prefix":"10.4103","volume":"26","author":[{"given":"Honglei","family":"Xu","sequence":"first","affiliation":[{"name":"Music College of Qufu Normal University, Rizhao 276826, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,3,23]]},"reference":[{"issue":"(1_suppl)","key":"R1-20240908","first-page":"S1","article-title":"Clinical practice guideline: hoarseness (dysphonia) (update)","volume":"158","author":"Stachler","year":"2018","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R2-20240908","first-page":"482","article-title":"\u201cDysmodulation\u201d rather than \u201cfunctional\u201d voice disorders: recommendation of the European Association of Voice Physicians","volume":"31","author":"Wang","year":"2019","journal-title":"J Audiol Speech Disord"},{"key":"R3-20240908","doi-asserted-by":"crossref","first-page":"156.e1","DOI":"10.1016\/j.jvoice.2018.07.027","article-title":"Characteristics of functional dysphonia in children","volume":"34","author":"Yang","year":"2020","journal-title":"J Voice"},{"key":"R4-20240908","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1007\/s00405-018-5090-5","article-title":"Self-perception of quality of life in patients with functional voice disorders: the effects of psychological and vocal acoustic variables","volume":"275","author":"Andrea","year":"2018","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"R5-20240908","doi-asserted-by":"crossref","first-page":"4909","DOI":"10.1007\/s00405-021-07021-y","article-title":"Effects of a conservative in-patient voice treatment on the voice-related self-concept","volume":"278","author":"Lehnert","year":"2021","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"R6-20240908","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1001\/jamaoto.2017.2618","article-title":"Indirect vs direct voice therapy for children with vocal nodules: a randomized clinical trial","volume":"144","author":"Hartnick","year":"2018","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"R7-20240908","first-page":"295","article-title":"Evaluation on the voice rehabilitation effect promoted by Akson therapy on cases following vocal cord polyp surgically removed [in Chinese]","volume":"23","author":"Minqi","year":"2015","journal-title":"Chin J Integr Trad Chin West Med Otolaryngol"},{"key":"R8-20240908","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1097\/00005537-200409000-00009","article-title":"Development and validation of the Voice Handicap Index-10","volume":"114","author":"Rosen","year":"2004","journal-title":"Laryngoscope"},{"key":"R9-20240908","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0892-1997(97)80026-4","article-title":"Test-retest study of the GRBAS scale: influence of experience and professional background on perceptual rating of voice quality","volume":"11","author":"De Bodt","year":"1997","journal-title":"J Voice"},{"key":"R10-20240908","first-page":"264","article-title":"Consistency analysis of the DSI and GRBAS evaluation on vocal fold polyp [in Chinese]","volume":"27","author":"Yang","year":"2019","journal-title":"Chin J Otolaryngol Integr Trad West Med"},{"key":"R11-20240908","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.pupt.2019.04.003","article-title":"Assessing laryngeal function and hypersensitivity","volume":"56","author":"Famokunwa","year":"2019","journal-title":"Pulm Pharmacol Ther"},{"key":"R12-20240908","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1590\/1413-81232018243.00502017","article-title":"Seeking the recognition of voice disorder as work-related disease: historical-political movement [in Portuguese]","volume":"24","author":"Masson","year":"2019","journal-title":"Cien Saude Colet"},{"key":"R13-20240908","doi-asserted-by":"crossref","first-page":"11776","DOI":"10.1038\/s41598-020-68754-0","article-title":"The physical significance of acoustic parameters and its clinical significance of dysarthria in Parkinson\u2019s disease","volume":"10","author":"Yang","year":"2020","journal-title":"Sci Rep"},{"key":"R14-20240908","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s40814-023-01317-y","article-title":"A mixed-method feasibility study of the use of the Complete Vocal Technique (CVT), a pedagogic method to improve the voice and vocal function in singers and actors, in the treatment of patients with muscle tension dysphonia: a study protocol","volume":"9","author":"McGlashan","year":"2023","journal-title":"Pilot Feasibility Stud"},{"key":"R15-20240908","first-page":"485","article-title":"Effect of delivery mode on objective and subjective aspects of voice","volume":"26","author":"Ko\u00e7ak","year":"2022","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"R16-20240908","first-page":"176","article-title":"Using thyroid cartilage in type I thyroplasty for treating unilateral vocal cord paralysis [in Chinese]","volume":"30","author":"Wang","year":"2022","journal-title":"J Audiol Speech Disord"},{"key":"R17-20240908","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.jvoice.2020.07.015","article-title":"Maximum phonation time normative values among Malaysians and its relation to body mass index","volume":"36","author":"Al-Yahya","year":"2022","journal-title":"J Voice"},{"key":"R18-20240908","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.jvoice.2019.02.005","article-title":"Measurement reliability of laryngeal resistance and mean flow rate in pediatric subjects","volume":"34","author":"Scholp","year":"2020","journal-title":"J Voice"},{"key":"R19-20240908","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/lio2.1016","article-title":"Patient reported outcome measures: the impact of environment on VHI-10 responses","volume":"8","author":"Kinberg","year":"2023","journal-title":"Laryngoscope Investig Otolaryngol"},{"key":"R20-20240908","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.jvoice.2021.02.007","article-title":"Examining relationships between GRBAS ratings and acoustic, aerodynamic and patient-reported voice measures in adults with voice disorders","volume":"37","author":"Fujiki","year":"2023","journal-title":"J Voice"},{"key":"R21-20240908","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1177\/0003489419837265","article-title":"Liuzijue Qigong: a voice training method for unilateral vocal fold paralysis patients","volume":"128","author":"Tang","year":"2019","journal-title":"Ann Otol Rhinol Laryngol"}],"container-title":["Noise and Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/nah.nah_99_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:30:41Z","timestamp":1787769041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/nah.nah_99_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":21,"journal-issue":{"issue":"120","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/nah.nah_99_23","relation":{},"ISSN":["1463-1741"],"issn-type":[{"value":"1463-1741","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-11-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-31","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}