{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:23:05Z","timestamp":1787844185561,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Stroke is a very rare complication of rhino-orbital mucormycosis. Here we report a series of 24 patients with stroke due to mucormycosis, of whom 20 had recent or concurrent COVID-19.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a prospective observational study done in a tertiary care center in southern India conducted during August\u2013October 2021.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>This study included 24 patients (recent COVID-19 infection in 10, concurrent COVID-19 in 10, and COVID-19-negative in 4). Poorly controlled diabetes was present in 22 patients. Altered sensorium was the most common presentation. Anterior circulation was involved in all patients, and watershed infarction was the most common pattern. Despite aggressive management, 22 patients died.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Stroke due to mucormycosis has a very poor prognosis, especially with concurrent or recent COVID-19 infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ni.ni_486_22","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T13:00:20Z","timestamp":1770123620000},"page":"S137-S141","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Stroke Due to Mucormycosis in Patients with Recent\/Concurrent COVID-19"],"prefix":"10.4103","volume":"74","author":[{"given":"Nidhish M","family":"Chandra","sequence":"first","affiliation":[{"name":"Department of General Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak S","family":"Amalnath","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil K","family":"Saxena","sequence":"additional","affiliation":[{"name":"Department of ENT, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak S","family":"Barathi","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bheemanathi H","family":"Srinivas","sequence":"additional","affiliation":[{"name":"Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"R1-20260514","doi-asserted-by":"crossref","first-page":"e1006408","DOI":"10.1371\/journal.ppat.1006408","article-title":"Molecular mechanisms of mucormycosis-The bitter and the sweet","volume":"13","author":"Baldin","year":"2017","journal-title":"PLoS Pathog"},{"key":"R2-20260514","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1080\/00365540410020794","article-title":"Fatal strokes in patients with rhino-orbito-cerebral mucormycosis and associated vasculopathy","volume":"36","author":"Thajeb","year":"2004","journal-title":"Scand J Infect Dis"},{"key":"R3-20260514","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.4103\/ijo.IJO_1565_21","article-title":"Epidemiology, clinical profile, management, and outcome of COVID-19-associated rhino-orbital-cerebral mucormycosis in 2826 patients in India \u2013 Collaborative OPAI-IJO study on mucormycosis in COVID-19 (COSMIC), report 1","volume":"69","author":"Sen","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"R4-20260514","doi-asserted-by":"crossref","first-page":"523","DOI":"10.3390\/microorganisms9030523","article-title":"Epidemiology of mucormycosis in India","volume":"9","author":"Prakash","year":"2021","journal-title":"Microorganisms"},{"key":"R5-20260514","doi-asserted-by":"crossref","first-page":"944.e9","DOI":"10.1016\/j.cmi.2019.11.021","article-title":"A multicentre observational study on the epidemiology, risk factors, management and outcomes of mucormycosis in India","volume":"26","author":"Patel","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"R6-20260514","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jinf.2021.12.039","article-title":"Risk factors for coronavirus disease-associated mucormycosis","volume":"84","author":"Arora","year":"2022","journal-title":"J Infect"},{"key":"R7-20260514","doi-asserted-by":"crossref","first-page":"ofz392","DOI":"10.1093\/ofid\/ofz392","article-title":"Invasive fungal carotiditis: A rare manifestation of cranial invasive fungal disease:Case series and systematic review of the literature","volume":"6","author":"Little","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"R8-20260514","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1007\/s12028-015-0186-x","article-title":"Mucor thrombus","volume":"24","author":"Scharf","year":"2016","journal-title":"Neurocrit Care"},{"key":"R9-20260514","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1182\/bloodadvances.2020003968","article-title":"Sustained prothrombotic changes in COVID-19 patients 4 months after hospital discharge","volume":"5","author":"von Meijenfeldt","year":"2021","journal-title":"Blood Adv"},{"key":"R10-20260514","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1161\/STROKEAHA.120.031786","article-title":"Acute ischemic stroke and COVID-19: An analysis of 27 676 patients","volume":"52","author":"Qureshi","year":"2021","journal-title":"Stroke"},{"key":"R11-20260514","doi-asserted-by":"crossref","first-page":"e575","DOI":"10.1212\/WNL.0000000000011611","article-title":"A prospective study of neurologic disorders in hospitalized patients with COVID-19 in New York City","volume":"96","author":"Frontera","year":"2021","journal-title":"Neurology"},{"key":"R12-20260514","first-page":"114","article-title":"Perineural spread of rhinocerebral mucormycosis","volume":"17","author":"McLean","year":"1996","journal-title":"AJNR Am J Neuroradiol"},{"key":"R13-20260514","doi-asserted-by":"crossref","first-page":"62","DOI":"10.4103\/tjo.tjo_72_18","article-title":"Central retinal artery occlusion as the presenting manifestation of invasive rhino-orbital-cerebral mucormycosis","volume":"10","author":"Bawankar","year":"2020","journal-title":"Taiwan J Ophthalmol"},{"key":"R14-20260514","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.4103\/ijo.IJO_1127_21","article-title":"Histopathological evidence of central retinal artery occlusion secondary to angio-invasive fungal infection amidst SARS-CoV-2 pandemic","volume":"69","author":"Kochar","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"R15-20260514","doi-asserted-by":"crossref","first-page":"106231","DOI":"10.1016\/j.jstrokecerebrovasdis.2021.106231","article-title":"Cerebrovascular involvement in mucormycosis in COVID-19 pandemic","volume":"31","author":"Kulkarni","year":"2022","journal-title":"J Stroke Cerebrovasc Dis"}],"container-title":["Neurology 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