{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:43:35Z","timestamp":1786653815383,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:p>Achondroplasia is an autosomal dominant disorder with defect in the ossification of the cartilage of long bones. Many bony abnormalities constitute its clinical features, with craniovertebral junction (CVJ) anomalies being one of most common issues which need to be addressed at the earliest. CVJ anomalies in individuals may cause neurovascular compression, which may warrant an early surgery to prevent catastrophic complications. Posterior circulation strokes secondary to CVJ anomalies are well known. We hereby present an unusual case of posterior circulation stroke in an achondroplastic dwarf who presented to our tertiary care centre. Prospective case study. The present case adds to the existing literature about one of the preventable causes of fatal posterior circulation strokes in the young. A high index of suspicion for neurovascular compression at the foramen magnum and early initiation of treatment in achondroplastic young individuals may have gratifying results.<\/jats:p>","DOI":"10.4103\/ni.ni_537_21","type":"journal-article","created":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T13:01:24Z","timestamp":1714568484000},"page":"399-402","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Cervicomedullary Compression in Achondroplasia: A Feared Complication and an Unforeseen Risk Factor of Posterior Circulation Stroke"],"prefix":"10.4103","volume":"72","author":[{"given":"Reshma S","family":"Shaik","sequence":"first","affiliation":[{"name":"Department of Neurology, Princess Esra Hospital, Deccan College of Medical Sciences, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandhya","family":"Manorenj","sequence":"additional","affiliation":[{"name":"Department of Neurology, Princess Esra Hospital, Deccan College of Medical Sciences, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sravan K","family":"Marapaka","sequence":"additional","affiliation":[{"name":"Department of Radiology, Princess Esra Hospital, Deccan College of Medical Sciences, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,30]]},"reference":[{"key":"R1-20260505","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13023-018-0972-6","article-title":"Achondroplasia: A comprehensive clinical review","volume":"14","author":"Pauli","year":"2019","journal-title":"Orphanet J Rare Dis"},{"key":"R2-20260505","doi-asserted-by":"crossref","first-page":"117","DOI":"10.2147\/TACG.S51485","article-title":"Optimal management of complications associated with achondroplasia","volume":"7","author":"Ireland","year":"2014","journal-title":"Appl Clin Genet"},{"key":"R3-20260505","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1016\/j.jstrokecerebrovasdis.2014.07.003","article-title":"Profile of patients with craniovertebral junction anomalies with posterior circulation strokes","volume":"23","author":"Kulkarni","year":"2014","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"R4-20260505","doi-asserted-by":"crossref","first-page":"520","DOI":"10.4103\/0028-3886.103204","article-title":"Bow hunter\u2019s stroke - 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