{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:38:51Z","timestamp":1786653531466,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Colloid cysts are known to cause neuropsychological impairment. However, the specific domains that are affected and their outcomes following excision are not studied in the past. In the current study, we evaluated different neuropsychological domains that are involved in colloid cyst patients and how they fared on long-term follow-up after the excision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A retrospective cohort of sixteen colloid cyst patients managed in a tertiary care center were included in the study. The clinical presentation, largest cyst diameter, and the presence of ventriculomegaly using the Evans index were noted on an MR brain imaging preoperatively. The neurocognitive evaluation was performed by a neuropsychologist at the presentation and 1 month and 1 year after the excision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The neuropsychological domains that were affected in colloid cyst patients are memory, rate of learning, verbal fluency, sustained attention, focused attention, information processing speed, auditory attention, and working memory. There was a clinically meaningful improvement in visual memory (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.054) and logical memory (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.058) in operated patients, while other parameters improved slightly. No significant change was noted in early and late postoperative neuropsychological assessments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Neurocognitive domains that are affected in colloid cyst patients are memory, rate of learning, verbal fluency, sustained attention, focused attention, information processing speed, auditory attention, and working memory. Visual memory and logical memory show sustained clinically meaningful improvement in long-term follow-up postsurgical decompression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/ni.ni_919_22","type":"journal-article","created":{"date-parts":[[2025,2,7]],"date-time":"2025-02-07T12:21:43Z","timestamp":1738930903000},"page":"77-81","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Neuropsychological Profiling of Colloid Cyst Patients: Domains Affected and Long-term Outcomes"],"prefix":"10.4103","volume":"73","author":[{"given":"K","family":"Sainadh","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Aster Medcity, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shejoy","family":"Joshua","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Aster Medcity, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayesha Sagir","family":"Manappat","sequence":"additional","affiliation":[{"name":"Department of Neuropsychology, Aster Medcity, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandhya","family":"Cherkil","sequence":"additional","affiliation":[{"name":"Department of Neuropsychology, Aster Medcity, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manas","family":"Chacko","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Aster Medcity, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilip","family":"Panikar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Aster Medcity, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,7]]},"reference":[{"key":"R1-20250713","first-page":"315","article-title":"Neuropsychiatric manifestations of colloid cysts: A review of the literature","volume":"27","author":"Lawrence","year":"2015","journal-title":"Psychiatr Danub"},{"key":"R2-20250713","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0090-3019(02)00701-2","article-title":"Surgical management of colloid cyst of the third ventricle--A study of 105 cases","volume":"57","author":"Desai","year":"2002","journal-title":"Surg Neurol"},{"key":"R3-20250713","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/BF01418468","article-title":"Colloid cysts of the third ventricle. A review of 36 cases","volume":"76","author":"Nitta","year":"1985","journal-title":"Acta Neurochir (Wien)"},{"key":"R4-20250713","first-page":"120","article-title":"Endoscopic resection of incidental colloid cysts clinical article","author":"Margetis","year":"2014","journal-title":"J Neurosurg"},{"key":"R7-20250713","first-page":"1","article-title":"Cognitive dysfunctions in patients with bipolar disorder: A comparative study from Western Rajasthan: Asian Journal of Medical Research","volume":"9","author":"Awasthi","year":"2020"},{"key":"R8-20250713","doi-asserted-by":"crossref","first-page":"110946","DOI":"10.1016\/j.brainresbull.2024.110946","article-title":"Brain morphological changes and functional neuroanatomy related to cognitive and emotional distractors during working memory maintenance in post-traumatic stress disorder","volume":"211","author":"Kim","year":"2024","journal-title":"Brain Research Bulletin"},{"key":"R9-20250713","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S0028-3932(02)00161-6","article-title":"Neuroimaging studies of semantic memory: Inferring \u201chow\u201d from \u201cwhere\u201d","volume":"41","author":"Thompson-Schill","year":"2003","journal-title":"Neuropsychologia"},{"key":"R10-20250713","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1177\/1073191115602552","article-title":"The trail making test","volume":"24","author":"Llin\u00e0s-Regl\u00e0","year":"2017","journal-title":"Assessment"},{"issue":"Supplement_8","key":"R11-20250713","doi-asserted-by":"crossref","first-page":"viii226","DOI":"10.1093\/neuonc\/noae165.0895","article-title":"NCOG-13. Assessing caregiver outcomes of primary brain tumor patients: A systematic review of the literature","volume":"26","author":"Walbert","year":"2024","journal-title":"Neuro-Oncology"},{"key":"R12-20250713","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1080\/23279095.2022.2104162","article-title":"Impaired recollection and initially preserved familiarity in a patient with bilateral fornix transection following third ventricle colloid cyst removal: A two-year follow-up study","volume":"31","author":"Fuentes","year":"2024","journal-title":"Applied Neuropsychology: Adult,"},{"key":"R13-20250713","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s10143-024-02410-3","article-title":"Comparison of decline in different cognitive domain in patients with normal pressure hydrocephalus","volume":"47","author":"R\u00fddlo","year":"2024","journal-title":"Neurosurgical Review"},{"key":"R14-20250713","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.18240\/ijo.2024.12.13","article-title":"Functional connectivity of paired default mode network subregions in patients with eye trauma","volume":"17","author":"Xing","year":"2024","journal-title":"International Journal of Ophthalmology"}],"container-title":["Neurology India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/ni.ni_919_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:38:56Z","timestamp":1786649936000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/ni.ni_919_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/ni.ni_919_22","relation":{},"ISSN":["0028-3886","1998-4022"],"issn-type":[{"value":"0028-3886","type":"print"},{"value":"1998-4022","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2022-09-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}