{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:05:32Z","timestamp":1787169932767,"version":"build-2736575974"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aim:<\/jats:title>\n                    <jats:p>Similar to the uncertainties in the treatment criteria for indolent non-Hodgkin lymphoma (iNHL), the prognostic criteria have not been fully clarified. The Controlled Nutritional Status (CONUT) score is not only used as a predictor of malnutrition but also indicates prognosis in many chronic or malignant diseases. The aim of this study is to investigate the predictive and prognostic significance of the CONUT score in patients with iNHL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>A retrospective evaluation was made of 109 patients with iNHL. The CONUT scores of the patients were compared between those with an indication for treatment and those followed without treatment. The same analysis was performed between patients who developed relapse after treatment. Survival analysis was performed on all patients, and associations between survival and the CONUT score were examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The median CONUT score was found to be higher in those who had treatment indications compared to those who did not (2 vs 1;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.014). In the regression model, a CONUT absolute value above 5 was found as an independent risk factor predicting relapse. In the whole study population, a CONUT absolute value &gt;2 predicted the risk of mortality with 53.9% sensitivity and 68.7% specificity (AUC \u00b1 SE = 0.639 \u00b1 0.07; +PV = 35%; -PV = 82.6%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.034).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>CONUT score is a predictive and prognostic factor for patients with iNHL. The development of simple, low-budget prognostic and predictive biomarkers is critical not only for determining the course of the disease but also for follow-up and treatment management.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_20_23","type":"journal-article","created":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T04:28:17Z","timestamp":1695356897000},"page":"1290-1296","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["The Utility of CONUT Score in Indolent Lymphoma Patients"],"prefix":"10.4103","volume":"26","author":[{"given":"M","family":"T\u0131\u011fl\u0131o\u011flu","sequence":"first","affiliation":[{"name":"Dr. Ers\u0131n Arslan Tra\u0131n\u0131ng and Research Hosp\u0131tal, Hematology, Gaz\u0131antep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HBA","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[{"name":"Ankara C\u0131ty Hosp\u0131tal, Hematology, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[{"name":"H\u0131t\u0131t Un\u0131vers\u0131ty, Hematology, Corum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"T\u0131\u011fl\u0131o\u011flu","sequence":"additional","affiliation":[{"name":"Dr. Ers\u0131n Arslan Tra\u0131n\u0131ng and Research Hosp\u0131tal, Hematology, Gaz\u0131antep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Ankara C\u0131ty Hosp\u0131tal, Hematology, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MR","family":"Aras","sequence":"additional","affiliation":[{"name":"Ankara C\u0131ty Hosp\u0131tal, Hematology, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Albayrak","sequence":"additional","affiliation":[{"name":"University of Health Sciences Diskapi Yildirim Beyazit Education and Research Hospital, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,9,21]]},"reference":[{"key":"R1-20240907","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.pop.2016.07.012","article-title":"Lymphoma","volume":"43","author":"Mugnaini","year":"2016","journal-title":"Prim Care"},{"key":"R2-20240907","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/PPO.0000000000000451","article-title":"Lymphoma classification","volume":"26","author":"de Leval","year":"2020","journal-title":"Cancer J"},{"key":"R3-20240907","doi-asserted-by":"crossref","first-page":"4617","DOI":"10.1182\/blood-2006-10-041863","article-title":"How I treat indolent lymphoma","volume":"109","author":"Gribben","year":"2007","journal-title":"Blood"},{"key":"R4-20240907","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12935-020-01535-x","article-title":"Prognostic nutritional index and the prognosis of diffuse large b-cell lymphoma:A meta-analysis","volume":"20","author":"Luan","year":"2020","journal-title":"Cancer Cell Int"},{"key":"R5-20240907","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.3906\/sag-2101-406","article-title":"Is CONUT score a prognostic index in patients with diffuse large cell lymphoma?","volume":"51","author":"\u00c7a\u011fliyan","year":"2021","journal-title":"Turk J Med Sci"},{"key":"R6-20240907","first-page":"38","article-title":"CONUT:A tool for controlling nutritional status. 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