{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:25:55Z","timestamp":1787761555323,"version":"build-2784847793"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and Aim:<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate radiographically the prevalence of mandibular nutrient canals (NCs) in patients with\/without periodontal bone loss with aging and to correlate the number of NCs with the severity of bone loss using cone-beam-computed tomography (CBCT).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods:<\/jats:title>\n                    <jats:p>CBCT examinations of 208 patients were evaluated retrospectively of all patients, 114 had periodontal bone loss, whereas 94 patients were control subjects. Alveolar bone loss investigations were performed according to the Progressive Rate Index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      NCs were observed in 55% of the control group and 86% of the periodontitis patients. NCs were more prevalent in the elderly age group with periodontal bone loss. In the study group, the NCs were statistically more frequent than in the control subjects (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Statistical analysis showed a significant difference between the age groups and the prevalence of NCs increased in patients with periodontal alveolar bone loss with aging (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_210_22","type":"journal-article","created":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T07:47:07Z","timestamp":1675237627000},"page":"59-64","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Cone-Beam-Computed Tomography Evaluation of Mandibular Nutrient Canals in Patients with Periodontal Diseases*"],"prefix":"10.4103","volume":"26","author":[{"given":"H","family":"Tumer","sequence":"first","affiliation":[{"name":"Department of Periodontology, Final International University, Faculty of Dentistry, Mersin 10, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Orhan","sequence":"additional","affiliation":[{"name":"Department of Dentomaxillofacial Radiology, University of Ankara, Faculty of Dentistry, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Department of Dentomaxillofacial Radiology, Near East University, Faculty of Dentistry, Mersin 10, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Berberoglu","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Ada Kent University, Faculty of Dentistry, Mersin 10, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,1,31]]},"reference":[{"key":"R1-20240907","first-page":"591","article-title":"The intraosseous course of the mandibular incisive nerve in the mandibular symphysis","volume":"21","author":"De Andrade","year":"2001","journal-title":"Int J Periodont Rest"},{"key":"R2-20240907","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/sj.dmfr.4600582","article-title":"Continuous radiographic visualization of the mandibular nutrient canals","volume":"30","author":"Wang","year":"2001","journal-title":"Dentomaxillofac Radiol"},{"key":"R3-20240907","first-page":"17","article-title":"Radiographic study of mandibular nutrient canal","volume":"51","author":"Bilge","year":"1992","journal-title":"Ann Dent"},{"key":"R4-20240907","doi-asserted-by":"crossref","first-page":"5","DOI":"10.5005\/jp-journals-10011-1079","article-title":"Evaluation of mandibular anterior nutrient canals in periodontal diseases: A prospective case control radiographic study","volume":"23","author":"Singh","year":"2011","journal-title":"J Indian Acad Oral Med Radiol"},{"key":"R5-20240907","first-page":"1123","article-title":"Periodontal disease and cardiovascular disease","volume":"67","author":"Beck","year":"1996","journal-title":"J Periodontol"},{"key":"R6-20240907","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1161\/01.STR.0000155734.34652.6c","article-title":"Radiographic measures of chronic periodontitis and carotid artery plaque","volume":"36","author":"Engebretson","year":"2005","journal-title":"Stroke"},{"key":"R7-20240907","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/0030-4220(85)90020-9","article-title":"Incidence of nutrient canals in hypertensive patients: A radiographic study","volume":"59","author":"Patni","year":"1985","journal-title":"Oral Surg, Oral Med and Oral Pathol"},{"key":"R9-20240907","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1259\/dmfr\/15644321","article-title":"Comparison of linear and angular measurements using two-dimensional conventional methods and three-dimensional cone beam CT images reconstructed from a volumetric rendering program in vivo","volume":"40","author":"Oz","year":"2011","journal-title":"Dentomaxillofac Radiol"},{"key":"R10-20240907","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/jcpe.12491","article-title":"Accuracy of periapical radiography in assessing bone level in implants affected by peri-implantitis: A cross-sectional study","volume":"43","author":"Garcia-Garcia","year":"2016","journal-title":"J Clin Periodontol"},{"key":"R11-20240907","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1259\/dmfr\/98032356","article-title":"Comparison of conventional and cone beam CT synthesized cephalograms","volume":"36","author":"Kumar","year":"2007","journal-title":"Dentomaxillofac Radiol"},{"key":"R12-20240907","first-page":"311","article-title":"Two-dimensional and three-dimensional cephalometry using cone beam computed tomography scans","volume":"26","author":"Michele","year":"2015","journal-title":"JCran Surg"},{"key":"R13-20240907","first-page":"458","article-title":"Computed tomography findings of mandibular nutrient canals","volume":"24","author":"Kawashima","year":"2015","journal-title":"Implant Dent"},{"key":"R14-20240907","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association. Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects","volume":"310","year":"2013","journal-title":"JAMA"},{"key":"R15-20240907","first-page":"4","article-title":"Rate-based analysis of untreated disease progression using the periodontitis progression rate index","volume":"6","author":"Craft","year":"1999","journal-title":"Periodontal Insights"},{"key":"R16-20240907","first-page":"37","article-title":"The periodontitis progression rate index: Methodologic considerations","volume":"6","author":"Craft","year":"2000","journal-title":"Periodontal Insights"},{"key":"R17-20240907","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/S0022-3913(96)90455-2","article-title":"A review of residual ridge resorption and bone density","volume":"75","author":"Klemetti","year":"1996","journal-title":"J Prosthet Dent"},{"key":"R18-20240907","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1741-2358.2004.00005.x","article-title":"Responses of jawbone to pressure","volume":"21","author":"Carlsson","year":"2004","journal-title":"Gerodontology"},{"key":"R19-20240907","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s00784-013-1011-6","article-title":"Number of accessory or nutrient canals in the human mandible","volume":"18","author":"Aps","year":"2014","journal-title":"Clin Oral Invest"},{"key":"R20-20240907","first-page":"24","article-title":"A radiographic study of mandibular nutrient canals in patients with Periodontal diseases","volume":"4","author":"Pandarinath","year":"2013","journal-title":"Int Arab J Dent"},{"key":"R21-20240907","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.tripleo.2009.10.023","article-title":"Comparison of cone-beam computerized tomography and intraoral radiographs for determination of the periodontal ligament in a variable phantom","volume":"109","author":"Jerv\u00f8e-Storm","year":"2010","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"R22-20240907","first-page":"1","article-title":"Comparison of intraoral radiography and cone-beam computed tomography for the detection of periodontal defects: An in vitro study","volume":"28","author":"Bagis","year":"2015","journal-title":"BMC Oral Health"},{"key":"R23-20240907","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1259\/dmfr\/26475758","article-title":"In vitro cone beam computed tomography imaging of periodontal bone","volume":"37","author":"Mol","year":"2008","journal-title":"Dentomaxillofac Radiol"},{"key":"R24-20240907","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1097\/RCT.0b013e3182436c6d","article-title":"Anatomical variations of neural canal structures of the mandible observed by 3-Tesla magnetic resonance imaging","volume":"36","author":"Krasny","year":"2012a","journal-title":"J Comput Assist Tomo"},{"key":"R25-20240907","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1007\/s00276-011-0910-y","article-title":"Study of inferior dental canal and its contents using high-resolution magnetic resonance imaging","volume":"34","author":"Krasny","year":"2012b","journal-title":"Surg Radiol Anat"},{"key":"R26-20240907","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00276-010-0719-0","article-title":"Detection of buccal perimandibular neurovascularisation associated with accessory foramina using limited cone-beam computed tomography and gross anatomy","volume":"33","author":"Fuakami","year":"2011","journal-title":"Surg Radiol Anat"},{"key":"R27-20240907","first-page":"53","article-title":"VEGF\/VEGFR2 axis in periodontal disease progression and angiogenesis: Basic approach for a new therapeutic strategy","volume":"30","author":"Vladau","year":"2016","journal-title":"In Vivo"},{"key":"R28-20240907","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1177\/154405910708600403","article-title":"Chemokines in oral inflammatory diseases: Apical periodontitis and periodontal disease","volume":"86","author":"Silva","year":"2007","journal-title":"J Dent Res"},{"key":"R29-20240907","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1034\/j.1600-0714.2000.291004.x","article-title":"Vascular remodelling in chronic inflammatory periodontal disease","volume":"29","author":"Chapple","year":"2000","journal-title":"J Oral Pathol Med"},{"key":"R30-20240907","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1902\/jop.1999.70.8.848","article-title":"Vascular endothelial growth factors and progression of periodontal diseases","volume":"70","author":"Johnson","year":"1999","journal-title":"JPeriodontol"},{"key":"R31-20240907","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.3390\/pathogens10101280","article-title":"Vascular changes and hypoxia in periodontal disease as a link to systemic complications","volume":"10","author":"Celik","year":"2021","journal-title":"Pathogens"},{"key":"R32-20240907","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/s11282-013-0138-0","article-title":"Cone-beam CT evaluation of morphology, location, and course of mandibular incisive canal: Considerations for implant treatment","volume":"30","author":"Orhan","year":"2014","journal-title":"Oral Radiol"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_210_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:01:42Z","timestamp":1787760102000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_210_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/njcp.njcp_210_22","relation":{},"ISSN":["1119-3077","2229-7731"],"issn-type":[{"value":"1119-3077","type":"print"},{"value":"2229-7731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-03-24","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-29","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}