{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:05:47Z","timestamp":1787169947894,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Vesicovaginal and rectovaginal fistulas may develop after pelvic metastasis of ovarian carcinoma. Purulent discharge from the vagina results in frequent vaginal or urinary tract infections, and triggers chronic inflammation. These incapacitating symptoms create serious medical and psychosocial problems, and result in low self-esteem and QoL. In this study, we present a metastatic ovarian cancer case admitted with bilateral nephrostomies, nonfunctioning colostomy, and high-volume recto- and vesicovaginal fistulas after debulking. She had frequent urinary tract infections and systemic inflammatory response syndrome. Surgery was performed successfully. However, we had to deal with complications, such as electrolyte imbalance, wound infection and continuing SIRS. Cumulative inflammatory burden caused by advanced carcinoma itself and its complications creates serious medical and psychosocial problems and should be managed with patience.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_212_22","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T02:31:13Z","timestamp":1692585073000},"page":"1762-1765","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Cumulative Inflammatory Burden Causing Multiple Complications after a Successful Pelvic Surgery for Advanced Ovarian Cancer"],"prefix":"10.4103","volume":"25","author":[{"given":"A","family":"Firat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-24-20240907","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ygyno.2018.11.007","article-title":"The road to long-term survival: Surgical approach and longitudinal treatments of long-term survivors of advanced-stage serous ovarian cancer","volume":"152","author":"Javellana","year":"2019","journal-title":"Gynecol Oncol"},{"key":"R2-24-20240907","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nrclinonc.2015.224","article-title":"Can advanced-stage ovarian cancer be cured?","volume":"13","author":"Narod","year":"2016","journal-title":"Nat Rev Clin Oncol"},{"key":"R3-24-20240907","first-page":"263","article-title":"Total pelvic exenteration for pelvic recurrence after advanced epithelial ovarian cancer: A case report and literature review","volume":"8","author":"Bacalbasa","year":"2015","journal-title":"J Med Life"},{"key":"R4-24-20240907","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.jogn.2017.04.134","article-title":"Problems experienced by ovarian cancer survivors during treatment","volume":"46","author":"Keim-Malpassi","year":"2017","journal-title":"J Obstet Gynecol Neonatal Nurs"},{"key":"R5-24-20240907","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2298\/ACI1401025D","article-title":"Surgical care vesicovaginal fistulas in women with malignant gynecological disease","volume":"61","author":"D\u017eami\u0107","year":"2014","journal-title":"Acta Chir Iugosl"},{"key":"R6-24-20240907","first-page":"693535","article-title":"Total pelvic exenteration for gynecologic malignancies","volume":"2012","author":"Diver","year":"2012","journal-title":"Int J Surg Oncol"},{"key":"R7-24-20240907","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1552-6909.2007.00180.x","article-title":"Postmenopausal women and the health consequences of obesity","volume":"36","author":"Dennis","year":"2007","journal-title":"J Obstet Gynecol Neonatal Nurs"},{"key":"R8-24-20240907","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.ygyno.2018.08.009","article-title":"Risk factors for septic adverse events and their impact on survival in advanced ovarian cancer patients treated with neoadjuvant chemotherapy and interval debulking surgery","volume":"151","author":"Son","year":"2018","journal-title":"Gynecol Oncol"},{"key":"R9-24-20240907","doi-asserted-by":"crossref","first-page":"133","DOI":"10.4240\/wjgs.v7.i8.133","article-title":"Operative considerations for rectovaginal fistulas","volume":"7","author":"Kniery","year":"2015","journal-title":"World J Gastrointest Surg"},{"key":"R10-24-20240907","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3892\/mco.2017.1266","article-title":"Factors favouring long-term survival following recurrence in ovarian cancer","volume":"7","author":"Soyama","year":"2017","journal-title":"Mol Clin Oncol"},{"key":"R11-24-20240907","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1634\/theoncologist.2015-0239","article-title":"Advanced ovarian cancer: primary or interval debulking? Five categories of patients in view of the results of randomized trials and tumor biology: Primary debulking surgery and interval debulking surgery for advanced ovarian cancer","volume":"21","author":"Makar","year":"2016","journal-title":"Oncologist"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_212_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:15:24Z","timestamp":1787166924000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_212_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":11,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/njcp.njcp_212_22","relation":{},"ISSN":["1119-3077"],"issn-type":[{"value":"1119-3077","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}