{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:18:10Z","timestamp":1787840290778,"version":"build-2784847793"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"\n Background:<\/jats:title>\n Osteoporotic vertebral compression fractures (OVCFs) represent the most common fragility fractures in the elderly population. These fractures frequently cause refractory back pain and progressive kyphosis, with subsequent high risks of vertebral refracture, ultimately leading to substantial disability, elevated mortality rates, and considerable socioeconomic burdens. Current therapeutic strategies prioritize minimally invasive approaches that are safe, technically feasible, and effective, with the primary goals of early functional recovery and quality of life restoration. Currently, the mainstream consensus favors minimally invasive surgical interventions.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n To compare the efficacy of percutaneous kyphoplasty (PKP) versus percutaneous 28 mesh-container-plasty (PMCP) for OVCF.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n The clinical data of 75 patients with thoracolumbar OVCF surgically treated in our hospital from March 2021 to March 2023 were reviewed and analyzed, of which 45 cases were treated with PKP, 30 cases were treated with PMCP, and the follow-up time was from 8 to 12 months. We compared the basic clinical data, surgical conditions, VAS (Visual Analog Scale), and ODI (Oswestry Disability Index) scores before and after surgery, the heights of the anterior and middle margins of the injured vertebrae, the Cobb angle of the injured vertebrae, and the leakage and distribution of bone cement between the two groups.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The VAS and ODI scores, the height, and the Cobb angle of the injured vertebrae of the two groups were improved compared with those of the preoperative period, and the difference was statistically significant (\n P<\/jats:italic>\n < 0.05). The PMCP group had longer operation time, larger amount of bone cement injection, more reasonable distribution, lower leakage rate, and better recovery of the vertebral height and the Cobb angle, compared with the PKP group, and the difference was statistically significant (\n P<\/jats:italic>\n < 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Both PKP and PMCP can effectively improve the pain symptoms and dysfunction of patients with OVCF, and the operation time of PMCP group is longer than that of the PKP group, but it can better improve the height and kyphosis of injured vertebrae, and the distribution of bone cement is more reasonable and the leakage rate is lower.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/njcp.njcp_22_24","type":"journal-article","created":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T01:00:58Z","timestamp":1748998858000},"page":"641-647","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy Analysis of PKP and PMCP in Treatment of Osteoporotic Vertebral Compression Fracture"],"prefix":"10.4103","volume":"28","author":[{"given":"L","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Suzhou Hospital, Affiliated Hospital of Medicine School, Nanjing University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Suzhou Hospital, Affiliated Hospital of Medicine School, Nanjing University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Suzhou Hospital, Affiliated Hospital of Medicine School, Nanjing University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Suzhou Hospital, Affiliated Hospital of Medicine School, Nanjing University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"He","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Suzhou Hospital, Affiliated Hospital of Medicine School, Nanjing University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Suzhou Hospital, Affiliated Hospital of Medicine School, Nanjing University, Suzhou, Jiangsu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,4]]},"reference":[{"issue":"Suppl 4","key":"R1-20260422","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1227\/NEU.0000000000000953","article-title":"The aging of the global population: The changing epidemiology of disease and spinal disorders","volume":"77","author":"Fehlings","year":"2015","journal-title":"Neurosurgery"},{"key":"R2-20260422","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.2147\/JPR.S375119","article-title":"A worldwide bibliometric analysis of published literature on osteoporosis vertebral compression fracture","volume":"15","author":"Li","year":"2022","journal-title":"J Pain Res"},{"key":"R3-20260422","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1007\/s00586-010-1479-6","article-title":"Recompression of vertebral body after balloon kyphoplasty for osteoporotic vertebral compression fracture","volume":"19","author":"Kim","year":"2010","journal-title":"Eur Spine J"},{"key":"R4-20260422","doi-asserted-by":"crossref","first-page":"E328","DOI":"10.1097\/BSD.0b013e31828f940c","article-title":"Comparison of clinical outcomes and radiographic measurements in 4 different treatment modalities for osteoporotic compression fractures: Retrospective analysis","volume":"28","author":"Ee","year":"2015","journal-title":"J Spinal Disord Tech"},{"key":"R5-20260422","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.pmr.2022.01.008","article-title":"Vertebroplasty and kyphoplasty","volume":"33","author":"Boss","year":"2022","journal-title":"Phys Med Rehabil Clin N Am"},{"key":"R6-20260422","doi-asserted-by":"crossref","first-page":"309","DOI":"10.36076\/ppj.2013\/16\/309","article-title":"Vertebral augmentation: Update on safety, efficacy, cost effectiveness and increased survival?","volume":"16","author":"Chandra","year":"2013","journal-title":"Pain Physician"},{"key":"R7-20260422","doi-asserted-by":"crossref","first-page":"1161174.","DOI":"10.3389\/fmed.2023.1161174","article-title":"Innovative minimally invasive implants for osteoporosis vertebral compression fractures","volume":"10","author":"Luo","year":"2023","journal-title":"Front Med (Lausanne)"},{"key":"R8-20260422","doi-asserted-by":"crossref","first-page":"e0151492.","DOI":"10.1371\/journal.pone.0151492","article-title":"Safety and efficacy studies of vertebroplasty, kyphoplasty, and mesh-container-plasty for the treatment of vertebral compression fractures: Preliminary report","volume":"11","author":"Chen","year":"2016","journal-title":"PLoS One"},{"key":"R9-20260422","doi-asserted-by":"crossref","first-page":"22","DOI":"10.5152\/j.aott.2021.20045","article-title":"Percutaneous mesh-container-plasty for osteoporotic thoracolumbar burst fractures: A prospective, nonrandomized comparative study","volume":"55","author":"Tang","year":"2021","journal-title":"Acta Orthop Traumatol Turc"},{"key":"R10-20260422","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1210\/jc.2011-3060","article-title":"Clinical review. Comparative effectiveness of drug treatments to prevent fragility fractures: A systematic review and network meta-analysis","volume":"97","author":"Murad","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"R11-20260422","first-page":"271","article-title":"The Oswestry low back pain disability questionnaire","volume":"66","author":"Fairbank","year":"1980","journal-title":"Physiotherapy"},{"key":"R12-20260422","first-page":"E805","article-title":"Comparison of unilateral and bilateral percutaneous kyphoplasty for bone cement distribution and clinical efficacy: An analysis using three-dimensional computed tomography images","volume":"25","author":"Zhang","year":"2022","journal-title":"Pain Physician"},{"key":"R13-20260422","first-page":"E411","article-title":"Clinical measurement of intravertebral pressure during vertebroplasty and kyphoplasty","volume":"16","author":"Wang","year":"2013","journal-title":"Pain Physician"},{"key":"R14-20260422","doi-asserted-by":"crossref","first-page":"451","DOI":"10.2214\/AJR.10.5937","article-title":"New vertebral compression fractures after prophylactic vertebroplasty in osteoporotic patients","volume":"197","author":"Kamano","year":"2011","journal-title":"AJR Am J Roentgenol"},{"key":"R15-20260422","first-page":"493","article-title":"The treatment of osteoporotic thoracolumbar severe burst fractures with short pedicle screw fixation and vertebroplasty","volume":"80","author":"He","year":"2014","journal-title":"Acta Orthop Belg"},{"key":"R16-20260422","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.spinee.2011.07.027","article-title":"Cement leakage in percutaneous vertebroplasty for osteoporotic vertebral compression fractures: Identification of risk factors","volume":"11","author":"Nieuwenhuijse","year":"2011","journal-title":"Spine J"},{"key":"R17-20260422","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.neurad.2013.07.004","article-title":"Analysis of intradiscal cement leakage during percutaneous vertebroplasty: Multivariate study of risk factors emphasizing preoperative MR findings","volume":"41","author":"Hong","year":"2014","journal-title":"J Neuroradiol"},{"key":"R18-20260422","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1097\/00007632-200107150-00002","article-title":"New technologies in spine: Kyphoplasty and vertebroplasty for the treatment of painful osteoporotic compression fractures","volume":"26","author":"Garfin","year":"2001","journal-title":"Spine (Phila Pa 1976)"},{"key":"R19-20260422","first-page":"200","article-title":"Kyphoplasty: An assessment of a new technology","volume":"28","author":"Cloft","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"key":"R20-20260422","doi-asserted-by":"crossref","first-page":"9509","DOI":"10.12998\/wjcc.v9.i31.9509","article-title":"Outcomes of different minimally invasive surgical treatments for vertebral compression fractures: An observational study","volume":"9","author":"Yeh","year":"2021","journal-title":"World J Clin Cases"},{"key":"R21-20260422","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1097\/00007632-200107150-00026","article-title":"Initial outcome and efficacy of \u201ckyphoplasty\u201d in the treatment of painful osteoporotic vertebral compression fractures","volume":"26","author":"Lieberman","year":"2001","journal-title":"Spine (Phila Pa 1976)"},{"key":"R22-20260422","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1080\/02688697.2020.1862054","article-title":"Vesselplasty for the treatment of osteoporotic vertebral compression fractures with peripheral wall damage: A retrospective study","volume":"38","author":"Chen","year":"2024","journal-title":"Br J Neurosurg"},{"key":"R23-20260422","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.acra.2005.05.003","article-title":"Intravertebral cleft sign on fat-suppressed contrast-enhanced MR: Correlation with cement distribution pattern on percutaneous vertebroplasty","volume":"12","author":"Oka","year":"2005","journal-title":"Acad Radiol"},{"key":"R24-20260422","doi-asserted-by":"crossref","first-page":"E1628","DOI":"10.1097\/BRS.0b013e3182a8c488","article-title":"Cluster phenomenon of vertebral refractures after percutaneous vertebroplasty in a patient with glucocorticosteroid-induced osteoporosis: Case report and review of the literature","volume":"38","author":"Sun","year":"2013","journal-title":"Spine (Phila Pa 1976)"},{"key":"R25-20260422","first-page":"495","article-title":"Percutaneous kyphoplasty evaluated by cement volume and distribution: An analysis of clinical data","volume":"19","author":"He","year":"2016","journal-title":"Pain Physician"},{"key":"R26-20260422","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1007\/s00264-015-2737-3","article-title":"Does balloon kyphoplasty improve the global spinal alignment in osteoporotic vertebral fracture?","volume":"39","author":"Kanayama","year":"2015","journal-title":"Int Orthop"},{"key":"R27-20260422","doi-asserted-by":"crossref","first-page":"e5.","DOI":"10.3171\/foc.2005.18.3.6","article-title":"Immediate and early postoperative pain relief after kyphoplasty without significant restoration of vertebral body height in acute osteoporotic vertebral fractures","volume":"18","author":"Feltes","year":"2005","journal-title":"Neurosurg Focus"},{"key":"R28-20260422","doi-asserted-by":"crossref","first-page":"202","DOI":"10.3174\/ajnr.A3617","article-title":"Analysis of related factors on the deformity correction of balloon kyphoplasty","volume":"35","author":"Xu","year":"2014","journal-title":"AJNR Am J Neuroradiol"},{"key":"R29-20260422","doi-asserted-by":"crossref","first-page":"669","DOI":"10.3174\/ajnr.A1442","article-title":"Kyphoplasty and vertebroplasty produce the same degree of height restoration","volume":"30","author":"Hiwatashi","year":"2009","journal-title":"AJNR Am J Neuroradiol"},{"key":"R30-20260422","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.otsr.2011.11.010","article-title":"Shield kyphoplasty through a unipedicular approach compared to vertebroplasty and balloon kyphoplasty in osteoporotic thoracolumbar fracture: A prospective randomized study","volume":"98","author":"Endres","year":"2012","journal-title":"Orthop Traumatol Surg Res"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_22_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:19:37Z","timestamp":1787836777000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_22_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/njcp.njcp_22_24","relation":{},"ISSN":["1119-3077","2229-7731"],"issn-type":[{"value":"1119-3077","type":"print"},{"value":"2229-7731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2024-01-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}