{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:43:20Z","timestamp":1786653800415,"version":"build-2736575974"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Parotid gland tumors constitute a significant proportion of head and neck neoplasms, and accurate non-invasive differentiation is essential for appropriate clinical management. Recent advances in ultrasound techniques, including shear-wave elastography (SWE), have shown promising diagnostic potential.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To evaluate the diagnostic performance of long-to-short axis ratio (L\/S) and shear-wave velocity (SWV) values obtained by virtual touch imaging quantification (VTIQ) in differentiating pleomorphic adenoma (PA), Warthin tumor (WT), and malignant tumors (MT) of the parotid gland.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This study included 66 parotid masses from 63 patients who underwent conventional ultrasound and SWE examinations. B-mode features, Doppler vascular patterns, L\/S ratios, and SWV values were recorded and compared with histopathological findings. Receiver operating characteristic (ROC) analysis was performed to determine optimal cutoff values, sensitivity, and specificity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The cutoff value for differentiating WT and PA was 1.57 for the L\/S ratio (sensitivity: 83.33%, specificity: 88.46%, p &lt; 0.001). For distinguishing MT from PA, the L\/S cutoff was 1.68 (sensitivity: 50.00%, specificity: 96.15%, p &lt; 0.001). The optimal SWV cutoff for WT and PA differentiation was 5.02 m\/s (sensitivity: 91.67%, specificity: 73.08%, p &lt; 0.001), while for MT and PA differentiation, it was 6.30 m\/s (sensitivity: 84.62%, specificity: 62.50%, p &lt; 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The combined use of L\/S ratio and SWV values obtained by VTIQ provides a reliable and non-invasive diagnostic approach for differentiating parotid gland tumors and may help reduce unnecessary biopsies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_22_26","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:00:06Z","timestamp":1777572006000},"page":"437-441","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Non-Invasive Characterization of Parotid Gland Tumors Using Imaging-Based Techniques"],"prefix":"10.4103","volume":"29","author":[{"given":"MG","family":"Demirci","sequence":"first","affiliation":[{"name":"Department of Radiology, Sanko University Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Ak\u015famo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gaziantep University Sahinbey Research and Practice Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MS","family":"Menzilcio\u011flu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gaziantep University Sahinbey Research and Practice Hospital, Gaziantep, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"R1-20260506","first-page":"175","article-title":"Ultrasonographic and sonoelastographic features of pleomorphic adenomas of the salivary glands","volume":"12","author":"Dumitriu","year":"2010","journal-title":"Med Ultrason"},{"key":"R2-20260506","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.6004\/jnccn.2014.0142","article-title":"National comprehensive cancer network. 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