{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:13:11Z","timestamp":1790115191734,"version":"4.0.1"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The aim of this in-vivo study was to evaluate the long-term clinical survival of different deep dentin caries treatment options.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>In total, 391 patients with at least one permanent tooth with clinically diagnosed deep dentin caries were inspected. Two hundred and fourteen patients were examined at recall visits. Inclusion criteria were teeth with deep caries lesions with pulp vitality but absence of spontaneous pain and periapical alterations. The subjects received either stepwise removal (SWR), complete caries removal (CCR), or direct pulp capping (DPC). The radiological and clinical exams were performed after a mean observation time of 62 months. Success was defined as pulp sensitivity to vitality test and absence of periapical lesions as well as a clinical symptom. Data were statistically analyzed using Kaplan\u2013Meier and log-rank (Mantel\u2013Cox) tests (\u03b1 = 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Of the total 214 patients evaluated, 126 received SWR, 88 received CCR, and 67 received DPC treatment. One hundred and twenty-seven restorations were amalgam and 141 were composite. The mean observation period was 62 months. Survival rates were 85.7%, 90.9%, and 59.7% for SWR, CCR, and DPC, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001). Success rates of amalgam restorations (86.6%) were similar to composite restorations (83%), and both were found to be successful (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.401).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>SWR treatment should be considered to preserve pulp vitality of deep dentin lesions instead of CCR or DPC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Relevance:<\/jats:title>\n                    <jats:p>SWR method for deep dentin caries management had acceptable results over 5 years.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/njcp.njcp_370_18","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T06:21:14Z","timestamp":1692598874000},"page":"117-124","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":11,"title":["Long-Term Survival of Different Deep Dentin Caries Treatments: A 5-Year Clinical Study"],"prefix":"10.4103","volume":"22","author":[{"given":"FD","family":"Oz","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry, Faculty of Dentistry, Hacettepe University, Altindag, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Bolay","sequence":"additional","affiliation":[{"name":"Karapurcek Dental Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"EO","family":"Bayazit","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Faculty of Medicine, Hacettepe University, Altindag, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CO","family":"Bicer","sequence":"additional","affiliation":[{"name":"Karapurcek Dental Hospital, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SY","family":"Isikhan","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Faculty of Medicine, Hacettepe University, Altindag, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20251006","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.14219\/jada.archive.1998.0428","article-title":"Pulp capping 1998","volume":"129","author":"Christensen","year":"1998","journal-title":"J Am Dent Assoc"},{"key":"R2-20251006","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1747-4477.2002.tb00364.x","article-title":"Vital pulp therapy in cariously exposed permanent teeth and its limitations","volume":"28","author":"Ward","year":"2002","journal-title":"Aust Endod J"},{"key":"R3-20251006","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/00004770-200009000-00010","article-title":"Pulp capping of carious exposures: Treatment outcome after 5 and 10 years: A retrospective study","volume":"26","author":"Barthel","year":"2000","journal-title":"J Endod"},{"key":"R4-20251006","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1600-0722.2010.00731.x","article-title":"Treatment of deep caries lesions in adults: Randomized clinical trials comparing stepwise vs. direct complete excavation, and direct pulp capping vs. partial pulpotomy","volume":"118","author":"Bjorndal","year":"2010","journal-title":"Eur J Oral Sci"},{"key":"R5-20251006","doi-asserted-by":"crossref","first-page":"705","DOI":"10.14219\/jada.archive.2008.0252","article-title":"Treatment of deep carious lesions by complete excavation or partial removal: A critical review","volume":"139","author":"Thompson","year":"2008","journal-title":"J Am Dent Assoc"},{"key":"R6-20251006","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1177\/0022034513500792","article-title":"Cost-effectiveness of one- and two-step incomplete and complete excavations","volume":"92","author":"Schwendicke","year":"2013","journal-title":"J Dent Res"},{"key":"R7-20251006","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1600-9657.1996.tb00513.x","article-title":"Pulp exposure after stepwise versus direct complete excavation of deep carious lesions in young posterior permanent teeth","volume":"12","author":"Leksell","year":"1996","journal-title":"Endod Dent Traumatol"},{"key":"R8-20251006","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1177\/0022034516639276","article-title":"Managing carious lesions: Consensus recommendations on terminology","volume":"28","author":"Innes","year":"2016","journal-title":"Adv Dent Res"},{"key":"R9-20251006","doi-asserted-by":"crossref","first-page":"476","DOI":"10.12968\/denu.2000.27.10.476","article-title":"The cartwright prize. Caries removal and the pulpo-dentinal complex","volume":"27","author":"Kidd","year":"2000","journal-title":"Dent Update"},{"key":"R10-20251006","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1159\/000077770","article-title":"How \u2018clean\u2019 must a cavity be before restoration?","volume":"38","author":"Kidd","year":"2004","journal-title":"Caries Res"},{"key":"R11-20251006","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1111\/j.1365-2591.1994.tb00257.x","article-title":"Dentine tubule infection and endodontic therapy implications","volume":"27","author":"Oguntebi","year":"1994","journal-title":"Int Endod J"},{"key":"R12-20251006","first-page":"197","article-title":"Attitudes and expectations of treating deep caries: A PEARL Network survey","volume":"55","author":"Oen","year":"2007","journal-title":"Gen Dent"},{"key":"R13-20251006","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/0030-4220(77)90086-X","article-title":"The affected and infected pulp","volume":"43","author":"Massler","year":"1977","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R14-20251006","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.joen.2010.12.004","article-title":"Vital pulp therapy in vital permanent teeth with cariously exposed pulp: A systematic review","volume":"37","author":"Aguilar","year":"2011","journal-title":"J Endod"},{"key":"R15-20251006","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1177\/0022034513477425","article-title":"Incomplete caries removal: A systematic review and meta-analysis","volume":"92","author":"Schwendicke","year":"2013","journal-title":"J Dent Res"},{"key":"R16-20251006","doi-asserted-by":"crossref","first-page":"607","DOI":"10.14219\/jada.archive.1978.0356","article-title":"Direct pulp capping treatment: A long-term follow-up","volume":"97","author":"Haskell","year":"1978","journal-title":"J Am Dent Assoc"},{"key":"R17-20251006","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/S0099-2399(96)80017-3","article-title":"A clinical study of direct pulp capping applied to carious-exposed pulps","volume":"22","author":"Matsuo","year":"1996","journal-title":"J Endod"},{"key":"R18-20251006","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.14219\/jada.archive.2006.0116","article-title":"The radiographic outcomes of direct pulp-capping procedures performed by dental students: A retrospective study","volume":"137","author":"Al-Hiyasat","year":"2006","journal-title":"J Am Dent Assoc"},{"key":"R20-20251006","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1016\/j.joen.2006.07.008","article-title":"A demographic analysis of vertical root fractures","volume":"32","author":"Cohen","year":"2006","journal-title":"J Endod"},{"key":"R22-20251006","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1159\/000442672","article-title":"Factors associated with reevaluation of the stepwise excavation procedure: An 8-year retrospective study","volume":"50","author":"Ortega-Verdugo","year":"2016","journal-title":"Caries Res"},{"key":"R23-20251006","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1159\/000016631","article-title":"Changes in the cultivable flora in deep carious lesions following a stepwise excavation procedure","volume":"34","author":"Bjorndal","year":"2000","journal-title":"Caries Res"},{"key":"R24-20251006","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1159\/000262431","article-title":"A clinical and microbiological study of deep carious lesions during stepwise excavation using long treatment intervals","volume":"31","author":"Bjorndal","year":"1997","journal-title":"Caries Res"},{"key":"R25-20251006","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1600-0528.1998.tb01938.x","article-title":"A practice-based study on stepwise excavation of deep carious lesions in permanent teeth: A 1-year follow-up study","volume":"26","author":"Bjorndal","year":"1998","journal-title":"Community Dent Oral Epidemiol"},{"key":"R26-20251006","first-page":"337","article-title":"Conservative treatment of deep carious lesions","volume":"37","author":"Jordan","year":"1971","journal-title":"J Can Dent Assoc (Tor)"},{"key":"R27-20251006","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1159\/000109349","article-title":"Deep caries lesions after incomplete dentine caries removal: 40-month follow-up study","volume":"41","author":"Maltz","year":"2007","journal-title":"Caries Res"},{"key":"R28-20251006","doi-asserted-by":"crossref","first-page":"459","DOI":"10.14219\/jada.archive.1982.0218","article-title":"Direct and indirect pulp capping with two new products","volume":"104","author":"Sawusch","year":"1982","journal-title":"J Am Dent Assoc"},{"key":"R29-20251006","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1752-7325.2003.tb03503.x","article-title":"Clinical evaluation of three restorative materials applied in a minimal intervention caries treatment approach","volume":"63","author":"Zanata","year":"2003","journal-title":"J Public Health Dent"},{"key":"R30-20251006","doi-asserted-by":"crossref","first-page":"547","DOI":"10.14219\/jada.archive.1980.0144","article-title":"Effect of improved Dycal and IRM on bacteria in deep carious lesions","volume":"100","author":"Fairbourn","year":"1980","journal-title":"J Am Dent Assoc"},{"key":"R31-20251006","doi-asserted-by":"crossref","first-page":"193","DOI":"10.14219\/jada.archive.1980.0056","article-title":"Effect of Dycal on bacteria in deep carious lesions","volume":"100","author":"Leung","year":"1980","journal-title":"J Am Dent Assoc"},{"key":"R32-20251006","first-page":"591","article-title":"A clinical, radiographic, and scanning electron microscopic evaluation of adhesive restorations on carious dentin in primary teeth","volume":"30","author":"Ribeiro","year":"1999","journal-title":"Quintessence Int"},{"key":"R33-20251006","doi-asserted-by":"crossref","first-page":"55","DOI":"10.14219\/jada.archive.1998.0022","article-title":"Ultraconservative and cariostatic sealed restorations: Results at year 10","volume":"129","author":"Mertz-Fairhurst","year":"1998","journal-title":"J Am Dent Assoc"},{"key":"R34-20251006","doi-asserted-by":"crossref","first-page":"312","DOI":"10.2341\/08-94","article-title":"Corrosion sealing of amalgam restorations in vitro","volume":"34","author":"Mahler","year":"2009","journal-title":"Oper Dent"},{"key":"R35-20251006","doi-asserted-by":"crossref","first-page":"161","DOI":"10.2341\/05-18","article-title":"Creep as a mechanism for sealing amalgams","volume":"31","author":"Osborne","year":"2006","journal-title":"Oper Dent"},{"key":"R36-20251006","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1590\/S1678-77572004000300002","article-title":"Bonding ability of adhesive resins to caries-affected and caries-infected dentin","volume":"12","author":"Yoshiyama","year":"2004","journal-title":"J Appl Oral Sci"},{"key":"R37-20251006","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1177\/154405910208100811","article-title":"Bonding of self-etch and total-etch adhesives to carious dentin","volume":"81","author":"Yoshiyama","year":"2002","journal-title":"J Dent Res"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01253091-201922010-00018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:59:53Z","timestamp":1786647593000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01253091-201922010-00018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.4103\/njcp.njcp_370_18","relation":{},"ISSN":["1119-3077","2229-7731"],"issn-type":[{"value":"1119-3077","type":"print"},{"value":"2229-7731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"2018-10-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}