{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:35:12Z","timestamp":1786649712527,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"\n Background:<\/jats:title>\n The HEART score is a risk stratification tool for acute chest pain, evaluating history, ECG, age, risk factors, and troponin. The SYNTAX (synergy between percutaneous coronary intervention with TAXUS and cardiac surgery) score assesses the extent and complexity of coronary artery disease (CAD) and is widely used in patients undergoing coronary interventions.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n To determine the relationship between the HEART and SYNTAX scores in patients with non-ST elevation myocardial infarction (NSTEMI).<\/jats:p>\n <\/jats:sec>\n \n Method:<\/jats:title>\n \n A total of 222 NSTEMI patients who underwent coronary angiography were included. The HEART score was calculated at admission, and all patients underwent angiography within 12 hours. SYNTAX was used to evaluate CAD severity. Patients were divided into two groups based on SYNTAX scores. Comparisons were made according to demographic data, laboratory findings, and risk factors. Variables associated with high SYNTAX scores were identified. A\n P<\/jats:italic>\n value of < 0.05 was considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The mean age was 63.67 \u00b1 11.89 years, and 74.77% of the patients were male. Patients with high SYNTAX scores had significantly higher HEART scores and more frequent diabetes and hypertension. High HEART score (OR: 3.09; 95% confidence intervals [CI]: 2.06\u20134.63;\n P<\/jats:italic>\n < 0.001) and diabetes mellitus (OR: 4.57; 95% CI: 1.44\u201314.47;\n P<\/jats:italic>\n = 0.010) were independently associated with high SYNTAX scores. A HEART score >7.5 predicted high SYNTAX scores with 82.1% sensitivity and 84.3% specificity (area under curve [AUC]: 0.892;\n P<\/jats:italic>\n < 0.001). A strong positive correlation was found between HEART and SYNTAX scores (\n P<\/jats:italic>\n < 0.001,\n R<\/jats:italic>\n \u00b2 =0.672).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The HEART score was significantly associated with the severity and complexity of CAD in patients with NSTEMI.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/njcp.njcp_417_24","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T01:00:10Z","timestamp":1750813210000},"page":"758-763","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["A Cross-Sectional Study on the Relationship between the HEART Score and the Severity of CAD using the SYNTAX Score in Patients with NSTEMI Admitted to the Emergency Department: A Study from Turkey"],"prefix":"10.4103","volume":"28","author":[{"given":"MS","family":"Pepele","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Inonu University, Malatya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Aktas","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Turgut Ozal University, School of Medicine, Malatya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O","family":"Demiroz","sequence":"additional","affiliation":[{"name":"University of Medical Sciences, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Derya","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Inonu University, Malatya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E","family":"Yildirim","sequence":"additional","affiliation":[{"name":"University of Medical Sciences, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MN","family":"Bilen","sequence":"additional","affiliation":[{"name":"Cam Sakura City Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Turgut Ozal University, School of Medicine, Malatya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"R1-20260422","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1093\/eurheartj\/ehm004","article-title":"Risk scores for risk stratification in acute coronary syndromes: Useful but simpler is not necessarily better","volume":"28","author":"Yan","year":"2007","journal-title":"Eur Heart J"},{"key":"R2-20260422","first-page":"219","article-title":"The SYNTAX Score: An angiographic tool grading the complexity of coronary artery disease","volume":"1","author":"Sianos","year":"2005","journal-title":"EuroIntervention"},{"key":"R3-20260422","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1080\/00015385.2020.1796319","article-title":"The relationship between H2FPEF and SYNTAX scores in patients with non-ST elevation myocardial infarction","volume":"76","author":"Bayam","year":"2021","journal-title":"Acta Cardiol"},{"key":"R4-20260422","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.amjcard.2016.06.024","article-title":"Usefulness of the baseline syntax score to predict 3-year outcome after complete revascularization by percutaneous coronary \u0131ntervention","volume":"118","author":"Kang","year":"2016","journal-title":"Am J Cardiol"},{"key":"R5-20260422","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/j.amjcard.2017.02.031","article-title":"Prognostic value of the clinical SYNTAX score on 2-year outcomes in patients with acute coronary syndrome who underwent percutaneous coronary \u0131ntervention","volume":"119","author":"He","year":"2017","journal-title":"Am J Cardiol"},{"key":"R6-20260422","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1016\/j.ijcard.2013.01.255","article-title":"A prospective validation of the HEART score for chest pain patients at the emergency department","volume":"168","author":"Backus","year":"2013","journal-title":"Int J Cardiol"},{"key":"R7-20260422","doi-asserted-by":"crossref","first-page":"267","DOI":"10.15441\/ceem.19.084","article-title":"The predictive value of HEART score for acute coronary syndrome and significant coronary artery stenosis","volume":"7","author":"Han","year":"2020","journal-title":"Clin Exp Emerg Med"},{"key":"R8-20260422","first-page":"e31","article-title":"HEART score in predicting one-month major adverse cardiac events in patients with acute chest pain; A diagnostic accuracy study","volume":"9","author":"Alimohammadi","year":"2021","journal-title":"Arch Acad Emerg Med"},{"key":"R9-20260422","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.tjem.2018.04.004","article-title":"The HEART score: A guide to its application in the emergency department","volume":"18","author":"Brady","year":"2018","journal-title":"Turk J Emerg Med"},{"key":"R10-20260422","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.ijcard.2016.10.080","article-title":"Comparison of the GRACE, HEART and TIMI score to predict major adverse cardiac events in chest pain patients at the emergency department","volume":"227","author":"Poldervaart","year":"2017","journal-title":"Int J Cardiol"},{"key":"R11-20260422","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.annemergmed.2018.12.010","article-title":"HEART score risk stratification of low-risk chest pain patients in the emergency department: A systematic review and meta-analysis","volume":"74","author":"Laureano-Phillips","year":"2019","journal-title":"Ann Emerg Med"},{"key":"R12-20260422","doi-asserted-by":"crossref","first-page":"7228","DOI":"10.1038\/s41598-023-34213-9","article-title":"The potential of HEART score to detect the severity of coronary artery disease according to SYNTAX score","volume":"13","author":"Salimi","year":"2023","journal-title":"Sci Rep"},{"key":"R13-20260422","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/acem.13649","article-title":"Prognostic accuracy of the HEART Score for prediction of major adverse cardiac events in patients presenting with chest pain: A systematic review and meta-analysis","volume":"26","author":"Fernando","year":"2019","journal-title":"Acad Emerg Med"},{"key":"R14-20260422","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/HPC.0b013e3181ec36d8","article-title":"Chest pain in the emergency room: A multicenter validation of the HEART Score","volume":"9","author":"Backus","year":"2010","journal-title":"Crit Pathw Cardiol"},{"key":"R15-20260422","doi-asserted-by":"crossref","first-page":"281","DOI":"10.36660\/abc.20190417","article-title":"Association between clinical risk score (Heart, Grace and TIMI) and angiographic complexity in acute coronary syndrome without ST segment elevation","volume":"117","author":"Cedro","year":"2021","journal-title":"Arq Bras Cardiol"},{"key":"R16-20260422","doi-asserted-by":"crossref","first-page":"57","DOI":"10.5152\/eurasianjmed.2021.20341","article-title":"Effectiveness of modified HEART score in predicting major adverse cardiac events","volume":"53","author":"Gur","year":"2021","journal-title":"Eurasian J Med"},{"key":"R17-20260422","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/eurheartj\/ehaa575","article-title":"2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation","volume":"42","author":"Collet","year":"2021","journal-title":"Eur Heart J"},{"key":"R18-20260422","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/j.jcin.2020.04.003","article-title":"Prognostic value of SYNTAX score in patients with \u0131nfarct-related cardiogenic shock: Insights from the CULPRIT-SHOCK trial","volume":"13","author":"Guedeney","year":"2020","journal-title":"JACC Cardiovasc Interv"}],"container-title":["Nigerian Journal of Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_417_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:57:28Z","timestamp":1786647448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/njcp.njcp_417_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/njcp.njcp_417_24","relation":{},"ISSN":["1119-3077","2229-7731"],"issn-type":[{"value":"1119-3077","type":"print"},{"value":"2229-7731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2024-06-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}